Results 121 to 130 of about 18,821 (231)
P2Y1 and P2Y12 receptors are class A G protein-coupled receptors and previous studies in the Kennedy lab suggested that they may physically interact to form functional heterodimers or possibly higher order oligomers. Little is known, however, about their
Klemm, Nicholas P.
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The DRY motif at work: the P2Y12 receptor case [PDF]
Journal of Thrombosis and Haemostasis, 2014 G. Rovati, V. Capra
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Brain and Behavior, Volume 16, Issue 6, June 2026.Atorvastatin combined with herb‐partitioned moxibustion significantly improved oxidative stress markers, blood rheology, vascular physiological function, and overall clinical efficacy in patients with atherosclerotic cerebral infarction while maintaining a favorable safety profile.
Wei An +9 more
wiley +1 more source
Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.Essential oil from Thymelaea tartonraira was characterized by GC–MS and evaluated using in vitro and in silico approaches. The oil exhibited notable antiplatelet activity with low cytotoxicity. Molecular docking revealed strong interactions of major compounds with GPVI, COX‐1, and P2Y12, supporting its potential as a natural antiplatelet agent ...
Siwar Soltani +8 more
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, 2017 Cardiovascular diseases, including in general affections of heart, brain, and blood vessels, are the leading worldwide cause of death with seventeen millions of deaths annually and a third part of them are due to thrombotic events.
Campuzano Maya, Germán
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Clinical Case Reports, Volume 14, Issue 6, June 2026.Visual Summary, case timeline of non‐ST‐elevation MI with PCI followed by cangrelor bridge for classical cesarean delivery. ABSTRACT Acute coronary syndrome is an uncommon but potentially life‐threatening complication in pregnancy, and dual antiplatelet therapy presents challenges in patients requiring cesarean delivery.
Vidya N. Mullangi +8 more
wiley +1 more source
Substituted 6-Amino-Thiouracils as new P2Y12 receptor antagonists
, 2007 Platelet adhesion and aggregation are pivotal events in arterial thrombosis thus making platelets the target of several important classes of antithrombotic agents.
BARBARA CACCIARI +5 more
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Clinical Cardiology, Volume 49, Issue 6, June 2026.ABSTRACT Background High‐intensity statins are standard therapy after percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS), yet tolerability concerns and residual cardiovascular risk remain important challenges. Moderate‐intensity statin therapy combined with ezetimibe has emerged as a potential alternative, although its ...
Emad Uddin Sajid +12 more
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The role of the purinergic receptor P2Y12 in Alzheimer's disease
Alzheimer’s disease (AD), the most common cause of dementia, shows a significant rise in prevalence due to increased global life expectancy and represents a major public health, social, and economic burden. Microglia, the resident immune cells of the CNS,
Maruccia, Riccardo
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, 2019 Background: Early administration of P2Y12-receptor inhibitors is recommended in all patients with acute coronary syndrome undergoing invasive management, with the aim to achieve the fastest and most effective platelet inhibition.
Campo G. +6 more
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