Results 71 to 80 of about 688,584 (205)
Expression of mRNAs for P2Y, P2Y, P2Y and P2Y nucleotide receptors in cerebellar astrocyte cultures
, 2011 Copyright information:Taken from "Cerebellar astrocytes co-express several ADP receptors. Presence of functional P2Y-like receptors"Purinergic Signalling 2005;1(2):153-159.Published online Jan 2005PMCID:PMC2096534.
Raquel Pérez-Sen (82291) +4 more
core +1 more source
ARF6-dependent regulation of P2Y receptor traffic and function in human platelets.
PLoS ONE, 2012 Adenosine diphosphate (ADP) is a critical regulator of platelet activation, mediating its actions through two G protein-coupled receptors, the P2Y(1) and P2Y(12) purinoceptors. Recently, we demonstrated that P2Y(1) and P2Y(12) purinoceptor activities are
Venkateswarlu Kanamarlapudi +4 more
doaj +1 more source
The FASEB Journal, Volume 40, Issue 19, 15 October 2026.Beta‐Arrestin‐2 but not Beta‐Arrestin‐1 can accumulate in the nucleolus and come in close contact with the Nucleolar Organizing Regions during two distinct processes: P2X7 receptor stimulation (A) and cell division (B). Both seem to be due to loss of nuclear membrane barrier that keeps Beta‐arrestin‐2 out of the nucleus.
Tuğba Gümüştaş +4 more
wiley +1 more source
Purinergic receptors in skeletal muscles in health and in muscular dystrophy [PDF]
, 2014 The P2 purinergic (nucleotide) receptor super-family comprises of two families of protein. The P2X, which are channel-forming ionotropic receptors and the P2Y metabotropic receptors activating G protein-mediated signalling pathways.
Young, Christopher +10 more
core
CX3CR1 Modulates Migration of Resident Microglia Towards Cortical Laser‐Induced Lesions
Glia, Volume 74, Issue 10, October 2026.CX3CR1 deficiency promotes microglial migration toward CNS injury. Proteomic profiling reveals altered RHO‐mediated cytoskeletal signaling, while in vivo two‐photon imaging demonstrates increased process extension, velocity, and accumulation of Cx3cr1‐deficient microglia at lesion sites. ABSTRACT Microglia are innate immune cells of the central nervous
Jens Wagner +13 more
wiley +1 more source
Glia, Volume 74, Issue 10, October 2026.Cell type–specific EVs were isolated from mouse brain and profiled by proteomics. Each EV subtype exhibited proteomic signatures consistent with the specialized functions of its cell of origin. Astrocyte‐derived EVs (ADEVs) were enriched for the GlialCAM/MLC1 network and GPCRs.
Alba M. Lucart‐Sanchez +7 more
wiley +1 more source
P2Y₂ Nucleotide Receptors Expressed Heterologously in Sympathetic Neurons Inhibit Both N-Type Ca²⁺ and M-Type K⁺ Currents [PDF]
, 1998 The P2Y₂ receptor is a uridine/adenosine triphosphate (UTP/ATP)-sensitive G-protein-linked nucleotide receptor that previously has been reported to stimulate the phosphoinositide signaling pathway.
Webb, TE +3 more
core
P2Y nucleotide receptors: promise of therapeutic applications.
, 2010 Extracellular nucleotides, such as ATP and UTP, have distinct signaling roles through a class of G-protein-coupled receptors, termed P2Y. The receptor ligands are typically charged molecules of low bioavailability and stability in vivo.
Boeynaems, Jean-Marie +1 more
core +1 more source
Journal of Extracellular Biology, Volume 5, Issue 10, October 2026.Experimental Design Overview Illustration to visualize the experimental structure (can be included in a graphical abstract later on)—Diagram / Workflow showing fish plasma collection, sample conditions: (a) volume groups (1 mL vs 2 mL or Midi vs Maxi); (b) Fresh vs frozen EV isolation→RNA extraction→Sequencing pipeline.
Antonio Espuela‐Ortiz +5 more
wiley +1 more source
UDP acts as a growth factor for vascular smooth muscle cells by activation of P2Y(6) receptors.
, 2002 Mitogenic effects of the extracellular nucleotides ATP and UTP are mediated by P2Y(1), P2Y(2), and P2Y(4) receptors. However, it has not been possible to examine the highly expressed UDP-sensitive P2Y(6) receptor because of the lack of stable, selective ...
Pendergast, William +12 more
core +2 more sources