Results 91 to 100 of about 688,584 (205)

Purine and purinergic receptors

Brain and Neuroscience Advances, 2018
Adenosine 5′-triphosphate acts as an extracellular signalling molecule (purinergic signalling), as well as an intracellular energy source. Adenosine 5′-triphosphate receptors have been cloned and characterised. P1 receptors are selective for adenosine, a
Geoffrey Burnstock
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Low-intensity pulsed ultrasound-dependent osteoblast proliferation occurs by via activation of the P2Y receptor: Role of the P2Y(1) receptor

, 2010
Low-intensity pulsed ultrasound (LIPUS) is commonly used in the treatment of fractures and nonunion-promoting acceleration of healing fractures. in this report, we investigated the implication of the P2 receptors in osteoblast proliferation induced with ...
Rodrigues, Renata [UNIFESP], Ferreira, Alice T. [UNIFESP], Silva-Filho, Fernando Costa, Alvarenga, Erika Costa [UNIFESP], Caricati-Neto, Afonso [UNIFESP], Paredes-Gamero, Edgar J. [UNIFESP], Renata Rodrigues, Afonso Caricati-Neto, Érika Costa Alvarenga, Alice T. Ferreira, Fernando Costa Silva-Filho, Edgar J. Paredes-Gamero   +11 more
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Expression of P2 receptors in human B cells and Epstein-Barr virus-transformed lymphoblastoid cell lines

BMC Immunology, 2006
Background Epstein-Barr virus (EBV) infection immortalizes primary B cells in vitro and generates lymphoblastoid cell lines (LCLs), which are used for several purposes in immunological and genetic studies. Purinergic receptors, consisting of P2X and P2Y,
Kim Jun Woo, Kong In Deok, Park Kyu Sang, Lee Dong Hyeon, Han Bok Ghee   +4 more
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Immunogold electron microscopic evidence of in situ formation of homo- and heteromeric purinergic adenosine A₁ and P2Y₂ receptors in rat brain

BMC Research Notes, 2010
Background Purines such as adenosine and ATP are now generally recognized as the regulators of many physiological functions, such as neurotransmission, pain, cardiac function, and immune responses.
Suzuki Tokiko, Namba Kazunori, Nakata Hiroyasu   +2 more
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Purine- and pyrimidine-induced responses and P2Y receptor characterization in the hamster proximal urethra

, 2005
1. Purine and pyrimidine compounds were investigated on hamster proximal urethral circular smooth muscle preparations. In situ hybridization studies were carried out to localize P2Y(1), P2Y(2), P2Y(4) and P2Y(6) mRNA. Protein expression was studied using
L. Puglisi, G. Burnstock, C. Pinna, KNIGHT GE, C. Bolego, PINNA C, BURNSTOCK G., GLASS R, PUGLISI L, BOLEGO, CHIARA, R. Glass, G. E. Knight   +11 more
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Anti-platelet therapy: ADP receptor antagonists. [PDF]

, 2011
The P2Y(12) receptor on platelets with which ADP interacts has an important role in promoting platelet function and thereby platelet involvement in both haemostasis and thrombosis.
Heptinstall, S, Wijeyeratne, YD, Stan Heptinstall, Yanushi Dullewe Wijeyeratne   +3 more
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Purinergic Signaling in Mast Cell Degranulation and Asthma

Frontiers in Pharmacology, 2017
Mast cells are responsible for the majority of allergic conditions. It was originally thought that almost all allergic events were mediated directly only via the high-affinity immunoglobulin E receptors.
Zhan-Guo Gao, Kenneth A. Jacobson
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Endothelin Type B Receptor–Induced Sustained Ca2+ Influx Involves Gq/11/Phospholipase C–Independent, p38 Mitogen-Activated Protein Kinase–Dependent Activation of Na+/H+ Exchanger

Journal of Pharmacological Sciences, 2010
The mechanism for sustained Ca2+ influx activated by G protein–coupled receptors was examined. In Chinese hamster ovary cells expressing recombinant human endothelin type B receptor (ETBR) and endogenous P2Y receptor (P2Y-R), endothelin-1 elicited a ...
Tsunaki Higa, Takahiro Horinouchi, Hiroyuki Aoyagi, Hiroshi Asano, Tadashi Nishiya, Arata Nishimoto, Ikunobu Muramatsu, Soichi Miwa   +7 more
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Purinergic receptors in the endocrine and exocrine pancreas [PDF]

, 2007
  Udgivelsesdato: 2007-Dec-11The pancreas is a complex gland performing both endocrine and exocrine functions. In recent years there has been increasing evidence that both endocrine and exocrine cells possess purinergic receptors, which influence ...
Novak, I, I. Novak
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Selective stimulation of catecholamine release from bovine adrenal chromaffin cells by an ionotropic purinergic receptor sensitive to 2-methylthio ATP

BMC Neuroscience, 2007
Background 2-Methylthioadenosine 5'-triphosphate (2-MeSATP), formerly regarded as a specific P2Y (metabotropic) purinergic receptor agonist, stimulates Ca2+ influx and evokes catecholamine release from adrenal chromaffin cells.
Castro Enrique, Tomé Ângelo R, Santos Rosa M, Rosário Luís M   +3 more
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