Results 11 to 20 of about 25,694 (216)
Pctaire1 Interacts with p35 and Is a Novel Substrate for Cdk5/p35 [PDF]
Journal of Biological Chemistry, 2002 Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that plays important roles during central nervous system development. Cdk5 kinase activity depends on its regulatory partners, p35 or p39, which are prominently expressed in the central nervous system. We have previously demonstrated the involvement of Cdk5 in the regulation of acetylcholine
Cheng, Kai +5 more
openaire +4 more sources
Sumoylation of p35 Modulates p35/Cyclin-Dependent Kinase (Cdk) 5 Complex Activity
NeuroMolecular Medicine, 2014 Cyclin-dependent kinase (Cdk) 5 is critical for central nervous system development and neuron-specific functions including neurite outgrowth as well as synaptic function and plasticity. Cdk5 activity requires association with one of the two regulatory subunits, called p35 and p39. p35 redistribution as well as misregulation of Cdk5 activity is followed
Büchner, A. +5 more
openaire +4 more sources
Resveratrol inhibits Cdk5 activity through regulation of p35 expression
Molecular Pain, 2011 Background We have previously reported that cyclin-dependent kinase 5 (Cdk5) participates in the regulation of nociceptive signaling. Through activation of the ERK1/2 pathway, Tumor Necrosis Factor-α (TNF-α) induces expression of Egr-1.
Kulkarni Ashok B +4 more
doaj +2 more sources
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on t(1;21)(p35;q22), with data on clinics, and the genes ...
Huret, JL
openaire +2 more sources
p35 interacts with α‐tubulin and organelle proteins: Nuclear translocation of p35 in dying cells
PROTEOMICS, 2009 AbstractWe identified heterogeneous nuclear ribonucleoprotein (hnRNP) C1/C2, hnRNP A1, the translocase of the transporter outer membrane 40 (TOM40), and α‐tubulin as new interaction partners of anti‐apoptotic protein p35 using MS‐based functional proteomics with GST‐p35 fusion protein as a bait, and using a pull‐down assay with p35‐6His followed by ...
Yonghae, Son +7 more
openaire +3 more sources
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on t(1;6)(p35;p25), with data on clinics, and the genes ...
Huret, JL
openaire +2 more sources
, 2008 The structure of the neutron-rich N=20 nucleus P35 has been investigated through nucleon transfer experiments using the 208Pb(36,Xγ) reaction at 230 MeV. The level structure, of mainly 1 ω excitations in P35, has been significantly expanded. The measurements are compared with shell model calculations.
Clark, R.M. +20 more
openaire +3 more sources
Microtubule Association of the Neuronal p35 Activator of Cdk5 [PDF]
Journal of Biological Chemistry, 2007 Cdk5 and its neuronal activator p35 play an important role in neuronal migration and proper development of the brain cortex. We show that p35 binds directly to alpha/beta-tubulin and microtubules. Microtubule polymers but not the alpha/beta-tubulin heterodimer block p35 interaction with Cdk5 and therefore inhibit Cdk5-p35 activity.
Hou, Z. +7 more
openaire +4 more sources
Repair of Acne Scars With Dermicol-P35 [PDF]
Aesthetic Surgery Journal, 2009 Acne vulgaris is a prevalent skin condition that can cause disfiguring residual scarring. While the complete removal of acne scars is unlikely, several treatments exist that can improve the appearance of acne scars. Dermal fillers offer a simple, nonsurgical corrective procedure that can provide improved skin texture.
Neil S, Sadick, Laura, Palmisano
openaire +5 more sources
PLoS ONE, 2014 Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase, which plays critical roles in a wide spectrum of neuronal functions including neuronal survival, neurite outgrowth, and synapse development and plasticity.
Xiao-Su Zhao +5 more
doaj +1 more source