Results 191 to 200 of about 327,693 (283)

p38 mitogen-activated protein kinase (MAPK14; p38 MAPK) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

RTA‐408 Enhances Radiosensitivity and Inhibited Tumor Progression via JNK Pathway in Glioblastoma

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Glioblastoma (GBM) is an aggressive brain tumor with poor prognosis owing to its high invasiveness and resistance to therapy. RTA‐408, a synthetic triterpenoid and nuclear factor erythroid 2‐related factor 2 activator, exhibits anti‐inflammatory and anti‐cancer properties; however, its effects on GBM remain unclear. This study investigated the
Hung‐Pei Tsai, Hao Qin, Yoon Bin Chong, I‐Hsiang Chen, Shih‐Hsun Kuo, Tzu‐Ting Tseng, Ann‐Shung Lieu   +6 more
wiley   +1 more source

Atypical p38 Kinase Signaling in Retinal Vascular Damage and Recovery. [PDF]

FASEB J
Schulz L, Young AE, Liu F, Gattineni S, Ghosh SS, Douglass E, Kroeger H, Narayanan SP, Grimsey NJ.   +8 more
europepmc   +1 more source

Matrine Attenuates Neurological Deficits and Neuroinflammation by Inhibiting the HMGB1/RAGE Axis and Ferroptosis in Intracerebral Hemorrhage Mice

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) is a life‐threatening stroke subtype that lacks effective drug therapy. In the context of ICH, neuroinflammation, and ferroptosis are key contributors to secondary brain injury. In this study, we assessed the neuroprotective effects of matrine (MAT) and its mechanism of action involving the HMGB1/RAGE axis in an ...
Pan‐Di Chen, Tao‐Tao Shi, Dan‐Yang Hu, Xiao‐Na Su, Jian‐Xiang Jin, Mao‐Song Chen, Hao Wang, Wei Chen   +7 more
wiley   +1 more source

PARP1 stabilizes FOXN3 to suppress pulmonary fibrosis through p38-related feedback regulation. [PDF]

Sci Adv
Zhu X, Huo Q, Jin L, Du J, Yu J, Wang H, Wu N, Li Y, Rui Y, Zhao C, Zhou J, Zhang Y, Li H, Lin J, Zheng C, Li W.   +15 more
europepmc   +1 more source

Combined Effects of Puerarin and Adipose‐Derived Stem Cells on Alveolar Bone Preservation and Inflammation Control in Periodontitis Through p38MAPK Modulation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study evaluated the effects of puerarin and adipose‐derived stem cells (ADSCs), alone or combined, on p38MAPK activity, alveolar bone preservation, and inflammatory responses in a rat periodontitis (PD) model and in vitro. ADSCs were exposed to various puerarin concentrations to assess cell proliferation, osteogenic differentiation, and ...
Ting Yang, Xu Zhang, Liang‐Fu Zhang
wiley   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

<i>CSRNP1</i> Promotes Apoptosis and Mitochondrial Dysfunction via ROS-Mediated JNK/p38 MAPK Pathway Activation in Hepatocellular Carcinoma. [PDF]

Oncol Res
Shi H, Chen L, Huang J, Lin X, Huang L, Tang M, Lu K, Wang W, Zhu M.   +8 more
europepmc   +1 more source

p38 mitogen-activated protein kinase (p38 MAPK; MAPK14) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Synthesis and Application of Chitosan‐Salicylic Acid Magnetic Nanoparticles in Colon Cancer Cells

Nano Select, EarlyView.
This study reports the development of magnetic nanoparticles using chitosan as a stabilizer and conjugated with salicylic acid for colon cancer therapy. The biocompatible design enhances nanoparticle stability and enables selective toxicity against cancer cells while minimizing effects on normal cells.
Aida Ebadi, Mahla Mohammadi, Mohammad Mehdi Ebadi, Sarah Mousavi, Mohammad Mashreghi, Ali Es‐Haghi, Mohammad Ehsan Taghavizadeh Yazdi, Hossein Behmadi, Mohammad Qandalee, Carlos J. Durán‐Valle, Ignacio M. López‐Coca   +10 more
wiley   +1 more source