Results 121 to 130 of about 229,819 (298)
5-MTP blocks p38 MAPK activation.
, 2016 (A) and (B) Activation of p38, Src and ERK½ was determined in HUVECs treated with VEGF or pro-inflammatory cytokines. Upper panels show representative blots and lower panels show the densitometry of p-p38 MAPK.
Yi-Fu Wang (1915039) +4 more
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Animal Research and One Health, EarlyView.Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang +6 more
wiley +1 more source
Telmisartan induces p38 MAPK and CREB phosphorylation in HUVECs.
, 2014 A. HUVECs were incubated with telmisartan for 15 min to 4 h to evaluate the phosphorylation levels of p38MAPK Thr180/Tyr182 and CREB Ser133. B. Relative phosphorylation levels of CREB calculated as the ratio of phospho-CREB (Ser133) to total CREB.
Daishi Fujita (564002) +10 more
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MDL‐800‐induced SIRT6 activation decreases age‐associated osteoarthritis in mice
Arthritis &Rheumatology, Accepted Article.Objective SIRT6 is a nuclear‐localized histone deacetylase that regulates multiple pathways associated with aging. This study aimed to determine whether systemic administration of a small molecule activator of SIRT6, MDL‐800, decreases the severity of age‐associated osteoarthritis (OA) in mice.
Matheus Moreira Perez +13 more
wiley +1 more source
, 2011 Copyright information:Taken from "Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-β-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy"http://www.molecular-cancer.com/content/6/1 ...
Tapas K Sengupta (33767) +5 more
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Clinical and Genetic Factors Associated With Regression in Children With Autism Spectrum Disorders
Autism Research, EarlyView.ABSTRACT Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition with complex genetic and environmental underpinnings. A clinically significant subset of children with ASD experience developmental regression (regASD), characterized by the acute loss of previously acquired skills. The mechanisms, predictors, and molecular basis of
Anna Maruani +7 more
wiley +1 more source
P38 mitogen-activated protein kinase (MAPK) in rheumatoid arthritis
, 2006 The importance of p38 MAPK inhibitors as new drug for rheumatoid arthritis is reflected by the large number of compounds that has been developed over the last years.
Limburg, P. C., Westra, J.
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Chemical structures of dual p38 and JNK MAPK inhibitors.
, 2013 Chemical structures of dual p38 and JNK MAPK inhibitors.
Allison D. Fryer (305649) +4 more
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Biotechnology and Bioengineering, EarlyView.ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu +3 more
wiley +1 more source
Phosphorylation of p38 MAPK following MP12 infection.
, 2013 A) 106 HSAECs were infected with MP12 (MOI of 3). Cell extracts were obtained at 0, 24, 48 and 72 h post infection and analyzed by western blot with anti-phospho-p38 antibody. Actin was used as loading control.
Jessica Kidd (238257) +8 more
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