Results 161 to 170 of about 229,819 (298)

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Tuberostemonine ameliorates Alzheimer's disease pathology by suppression of the p38 MAPK signaling pathway. [PDF]

iScience
Li Y, Xu X, Meng Z, Chen L, Yu Q, Wang R, Ren Y, Chen F, Liang G, Zhao X, Yu H, Wei J.   +11 more
europepmc   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

Lipoprotein (a) fuels EV71 replication by activating p38 MAPK-autophagy axis. [PDF]

Front Immunol
Deng L, Chen L, Ren M, Liang Y, He G, Tang X, Yang T, Xu J, Long T, Zhao Q, Wang B.   +10 more
europepmc   +1 more source

P38 MAPK Inhibitor LY3007113 [PDF]

, 2020
openaire   +1 more source

Polyphenol dietary supplementation prevents inflammation‐induced muscle atrophy in a zebrafish (Danio rerio) model

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Diet‐induced inflammation is a major cause of muscle degeneration impacting human and animal health. Owing to their anti‐inflammatory and antioxidant properties, polyphenols have attracted considerable interest as feed additives.
Graziella Orso, Monica Matuozzo, Mariapina Rocco, Seyed Hossein Hoseinifar, Ghasem Ashouri, Andrea Scaloni, Marina Paolucci, Chiara D'Ambrosio, Roberta Imperatore   +8 more
wiley   +1 more source

LMTK2 Inhibits Metastasis of Colon Cancer Cells Through p38 MAPK. [PDF]

Cancer Sci
Lun J, Zhang J, Xu J, Jing L, Qin Y, Fang J, Yu M.   +6 more
europepmc   +1 more source

Nuclear localization of p38 MAPK in response to DNA damage

, 2016
p38 MAP kinase (MAPK) is activated in response to environmental stress, cytokines and DNA damage, and mediates death, cell differentiation and cell cycle checkpoints.
Davis, Roger J., Sabio, Guadalupe, Rincon, Mercedes, Thornton, Tina, Wood, C. David   +4 more
core  

Andrographolide Modulates Fibrogenic and Oxidative Stress Responses in Human Lung Fibroblasts

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pulmonary fibrosis is a progressive lung disorder characterized by fibroblast activation and excessive extracellular matrix deposition. Andrographolide (ANDRO) has been reported to attenuate pulmonary fibrosis, but the underlying molecular mechanisms remain incompletely understood.
Yu‐Hsin Tseng, Yen‐Hsien Wu, Yi‐Ching Liu, I‐Chen Chen, Chung‐Yu Yeh, Shang‐En Huang, Ren‐Long Jan, Jwu‐Lai Yeh, Jong‐Hau Hsu   +8 more
wiley   +1 more source

Irradiation-Induced CD62L Shedding in Human Plasmacytoid Dendritic Cells Depends on ADAM17 and p38 MAPK. [PDF]

Immunology
Leplus E, Kacher J, Hannani D, Vayssiere G, Molens JP, Laulanier K, Georgess D, Josserand V, Saas P, Planel S, Chaperot L, Plumas J.   +11 more
europepmc   +1 more source