Results 201 to 210 of about 183,974 (371)

Intermittent Fasting‐Induced Orm2 Promotes Adipose Browning via the GP130/IL23R‐p38 Cascade

Advanced Science
Intermittent fasting (IF) plays a critical role in mitigating obesity, yet the precise biological mechanisms require further elucidation. Here Orosomucoid 2 (Orm2) is identified as an IF‐induced hepatokine that stimulates adipose browning.
Xuejuan Zhu, Xinran Wang, Jingang Wang, Lei Du, Zhen‐Ning Zhang, Donglei Zhou, Junfeng Han, Bing Luan   +7 more
doaj   +1 more source

Transient anoxia and oxyradicals induce a region-specific activation of MAPKs in the embryonic heart [PDF]

, 2018
We have previously reported in the early septating embryonic heart that electromechanical disturbances induced by anoxia-reoxygenation are distinct in atria, ventricle, and outflow tract, and are attenuated in ventricle by opening of mitochondrial KATP ...
Gardier, Stephany, Pedretti, Sarah, Raddatz, Eric, Sarre, Alexandre   +3 more
core  

Iron suppresses ovarian granulosa cell proliferation and arrests cell cycle through regulating p38 mitogen-activated protein kinase/p53/p21 pathway [PDF]

, 2017
Mei‐Jou Chen, Chia-Hong Chou, Chia‐Tung Shun, Tsui-Lien Mao, Wen-Fen Wen, Chin‐Der Chen, Shee‐Uan Chen, Yu‐Shih Yang, Hong‐Nerng Ho   +8 more
openalex   +1 more source

Data from Activation of p38 Mitogen-Activated Protein Kinase Is Required for Death Receptor–Independent Caspase-8 Activation and Cell Death in Response to Sphingosine

, 2023
Changhwan Yoon, Minjung Kim, Moon-Taek Park, Joo‐Yun Byun, Young-Hyun Choi, Hwan‐Soo Yoo, Yong-Moon Lee, Jin Won Hyun, Su‐Jae Lee   +8 more
openalex   +1 more source

The Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinases MK2 and MK3 Cooperate in Stimulation of Tumor Necrosis Factor Biosynthesis and Stabilization of p38 MAPK

Molecular and Cellular Biology, 2006
Natalia Ronkina, A. Kotlyarov, O. Dittrich‐Breiholz, M. Kracht, E. Hitti, K. Milarski, R. Askew, S. Marušić, Lih-Ling Lin, M. Gaestel, J. Telliez   +10 more
semanticscholar   +1 more source

p38 mitogen-activated protein kinase (MAPK14; p38 MAPK) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Expression characteristics of dual‐specificity phosphatase 2 and hypoxia‐inducible factor‐1α in acute kidney injury and preliminary study of the effect of dual‐specificity phosphatase 2 on HK‐2 cells

Experimental Physiology, EarlyView.
ABSTRACT Acute kidney injury (AKI) is a global health problem with significant long‐term harm if the prognosis is poor. Dual‐specificity phosphatase 2 (DUSP2) is involved in key regulatory pathways in several disease processes, but its function in renal pathophysiology is unclear.
Xueqian Chu, Songmin Xue, Lanyan Lin, Xuan Huang, Sisi Chen, Wulaer Adeli, Zulibiya Tuohetiyaer, Suhua Li, Chen Lu   +8 more
wiley   +1 more source

Independent regulation of JNK/p38 mitogen-activated protein kinases by metabolic oxidative stress in the liver.

Proceedings of the National Academy of Sciences of the United States of America, 1996
K. G. Mendelson, Contois Lr, Tevosian Sg, Davis Rj, Paul C. Ke   +4 more
semanticscholar   +1 more source

The skeletal muscle–adipose creatine metabolic axis: A novel paradigm for lipid metabolism reprogramming and obesity management

Experimental Physiology, EarlyView.
Abstract The global prevalence of obesity and related metabolic disorders has spurred interdisciplinary research to develop new intervention strategies. Current research is increasingly focusing on the exercise‐induced browning of white adipose tissue and the mechanisms by which it improves energy metabolism.
Yuhui Su, Na Liu, Yang Liu, Yiqun Sun, Yike Jiao   +4 more
wiley   +1 more source

Role of the p38 Mitogen-Activated Protein Kinase/Cytosolic Phospholipase A₂ Signaling Pathway in Blood—Brain Barrier Disruption after Focal Cerebral Ischemia and Reperfusion [PDF]

, 2008
Chikako Nito, Hiroshi Kamada, Hidenori Endo, Kuniyasu Niizuma, D. Jeannie Myer, Pak H. Chan   +5 more
openalex   +1 more source