Results 211 to 220 of about 58,168 (261)

Interferon‐induced transmembrane (IFITM) proteins at the tumour–immune interface: A four‐axis framework for their context‐dependent roles

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Interferon‐induced transmembrane (IFITM) function in cancer is set by four contextual coordinates, not by family membership. Acute interferon input drives major histocompatibility complex class I (MHC‐I)‐linked immunogenicity; chronic input drives programmed death‐ligand 1 (PD‐L1)‐coupled resistance.
Zhe Liu, Jie Meng, Zengyan Lai, Fuqiu Li, Sha Lv   +4 more
wiley   +1 more source

Immune regulation of Chidamide-induced Linc01010 accumulation in breast cancer cell death. [PDF]

World J Clin Oncol
Han H, Guo XY, Wen JX, Zhao XM, Zhou WQ.
europepmc   +1 more source

Neutrophil‐based immunotherapy: A metabolic lens on mechanisms and therapeutic implications

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
TAN metabolic reprogramming critically contributes to tumour immune evasion. A 4‑Tier TAN‑MetaC classification framework is proposed, along with an overview of translational opportunities and bottlenecks for TAN metabolism‑targeted immunotherapies. Abstract Background Tumor‐associated neutrophils (TANs) serve as pivotal immune modulators in the tumor ...
Wenchao Xu, Yu Su, Li Zhou, Jianzhou Liu, Junchao Guo   +4 more
wiley   +1 more source

Autophagy-Apoptosis Crosstalk in Cancer: Mechanisms, Signaling Pathways, and Therapeutic Targeting. [PDF]

Cancers (Basel)
Kakkar D, Saxena S, Dhawan U, Dosi N, Khanna C, Paul S.   +5 more
europepmc   +1 more source

Mechanisms of Lycium barbarum Treatment in Sepsis‐Induced Myocardial Injury: A Network Pharmacology and Experimental Validation Study

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
The chemical characterization of the LB extract confirmed the presence of polysaccharides and specific small‐molecule constituents (e.g., rutin, isoquercitrin). Network pharmacology analysis predicted that the bioactive components of LB were able to interact with core targets such as TP53, AKT1, and JUN, and molecular docking simulations suggested ...
Ruxin Liu, Chunxia Ma, Yujiao Tang, Xue Bai, Liting Yang, Yi Hu, Zesu Niu, Weiliang Xue, Ling Zhang, Mengfei Chen   +9 more
wiley   +1 more source

Regulation of Cell Proliferation and Migration by Extracellular Phosphatidic Acid. [PDF]

Biomedicines
Gomez-Larrauri A, Benito-Vicente A, Uribe KB, Martin C, Gomez-Muñoz A.   +4 more
europepmc   +1 more source

Clinical and Functional Significance of p38δ (MAPK13) in Lung Cancer. [PDF]

Cancer Genomics Proteomics
Sumar M, Fleming TP, Bremner RM, Sankpal NV.   +3 more
europepmc   +1 more source

Mitogen-Activated Protein Kinases: Therapeutic Signaling Catalysts in Viral Immune Evasion. [PDF]

Pathogens
Khan MA, Khan MH, Allemailem KS.
europepmc   +1 more source

An inhibitor of GCN2 and the integrated stress response directly targets ZAK protein kinase to limit cytotoxicity. [PDF]

J Biol Chem
Misra J, Spandau DF, Vilseck JZ, Anthony TG, Staschke KA, Wek RC.   +5 more
europepmc   +1 more source

Inhibition of inflammation and senescence with azole compound C7 enables expansion of hematopoietic stem and progenitor cells. [PDF]

Stem Cells Transl Med
Kok ZH, Lee LM, Liu KYH, Ouyang J, Rajasegaran V, Lim SPS, Loh JW, Lee JY, Lim AH, Ng CCY, Chan JY, Bari S, Hwang WYK.   +12 more
europepmc   +1 more source