Results 91 to 100 of about 90,894 (265)

Methods and compositions for stimulating T-lymphocytes [PDF]

open access: yes, 2003
Disclosed are methods, compositions, antibodies, and therapeutic kits for use in stimulating cytotoxic T-lymphocytes and generating immune responses against epitopes of protooncogenes.
Fisk, Bryan A.   +2 more
core   +1 more source

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis   +9 more
wiley   +1 more source

An examination of the putative glucose tolerance factor activity of amino acid and peptide fractions isolated from brewer's yeast : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Chemistry at Massey University [PDF]

open access: yes, 1985
The first report of the possible existance of a glucose tolerance factor (GTF) was made by Mertz and Schwarz (1955) who noticed that a dietary additive, termed factor 3, isolated from an enzymatic casein hydrolysate (Schwarz (1952)), maintained normal ...
Jackson, Timothy Graham
core  

ATP as a presynaptic modulator [PDF]

open access: yes, 2000
© 2000 Elsevier Science Inc.There is considerable evidence that ATP acts as a fast transmitter or co-transmitter in autonomic and sensory nerves mostly through activation of ionotropic P2X receptors but also through metabotropic P2Y receptors. By analogy,
Cunha, Rodrigo A., Ribeiro, J. A.
core   +1 more source

Development of natural and unnatural amino acid delivery systems against hookworm infection

open access: yesPrecision Nanomedicine, 2020
Peptide-based vaccines consist of short antigen fragments derived from a specific pathogen. Alone, these peptide fragments are poorly or non-immunogenic; however, when incorporated into a proper delivery system, they can trigger strong immune responses.
Stacey Bartlett   +5 more
doaj   +1 more source

Effect of HIV infection and antiretroviral therapy on hepatitis B virus (HBV)-specific T cell responses in patients who have resolved HBV infection [PDF]

open access: yes, 2005
Coinfection with hepatitis B virus (HBV) is a common occurrence in human immunodeficiency virus (HIV)–positive patients and an increasing cause of morbidity and mortality.
Bertoletti, A.   +9 more
core   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

open access: yesAnimal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang   +6 more
wiley   +1 more source

The identification of a SARs-CoV2 S2 protein derived peptide with super-antigen-like stimulatory properties on T-cells

open access: yesCommunications Biology
Severe COVID-19 can trigger a cytokine storm, leading to acute respiratory distress syndrome (ARDS) with similarities to superantigen-induced toxic shock syndrome.
Thai Hien Tu   +10 more
doaj   +1 more source

Clostridium perfringensepsilon toxin H149A mutant as a platform for receptor binding studies [PDF]

open access: yes, 2013
Clostridium perfringens epsilon toxin (Etx) is a pore-forming toxin responsible for a severe and rapidly fatal enterotoxemia of ruminants. The toxin is classified as a category B bioterrorism agent by the U.S.
Abe   +40 more
core   +1 more source

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still's Disease‐like Autoinflammatory Syndrome

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives Still's Disease represents a prototypical polygenic systemic autoinflammatory diseases (SAIDs), characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still's disease remains unreported.
Longfang Chen   +23 more
wiley   +1 more source

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