Results 51 to 60 of about 29,802 (177)

An Ulcerated Nodule on the Scalp

open access: yes
JEADV Clinical Practice, EarlyView.
Zainab Asghar   +2 more
wiley   +1 more source

When Small Cells Matter: Diagnosing Bladder Small Cell Carcinoma on Urine Cytology

open access: yesCytopathology, EarlyView.
Small cell carcinoma of the bladder is rare, aggressive and diagnostically challenging on urine cytology. We report a case detected in urine and confirmed by cell block immunohistochemistry, highlighting the importance of careful assessment and limitations of the Paris System.
Haley Corbin   +3 more
wiley   +1 more source

Enlarging Fingertip Nodule Mimicking a Pyogenic Granuloma in a Man in his 60's

open access: yes
JEADV Clinical Practice, EarlyView.
Avery H. Seward   +2 more
wiley   +1 more source

World Health Organization classification of tumours of the breast 6th edition 2026

open access: yesHistopathology, EarlyView.
The 6th edition of the World Health Organization Classification of Breast Tumours introduces changes based on recent advances in our understanding of breast biology, developments in diagnostic modalities, identification of specific molecular targets and new treatment regimes.
Cecily Quinn   +47 more
wiley   +1 more source

Marked attenuation of P63 expression in plasmacytoid urothelial carcinoma with expanded immunohistochemical framework including E‐cadherin, P120, HER2 and TRPS1

open access: yesHistopathology, EarlyView.
Plasmacytoid urothelial carcinoma demonstrates marked attenuation of p63 expression together with frequent disruption of the E‐cadherin–p120 adhesion complex, supporting its characteristic discohesive growth pattern. Standardized HER2 scoring identifies a substantial positive subset, highlighting diagnostic pitfalls and potential therapeutic relevance ...
Busra Yaprak Bayrak   +22 more
wiley   +1 more source

Unveiling the molecular profile of adenosquamous gallbladder carcinoma: characterization of a Caucasian cohort

open access: yesHistopathology, EarlyView.
GBASCs are MMRp tumours, exhibiting minimal HER2 overexpression and elevated PD‐L1 expression compared to adenocarcinomas. Especially in metastatic and TP53‐wild type tumours, GBASCs can express CLDN18, albeit limited to the glandular component. Their genomic profile resembles that of adenocarcinomas with an enrichment in alterations on PIK3CA, PTEN ...
Jessica Gasparello   +20 more
wiley   +1 more source

NFE2L2‐mutated urothelial carcinomas frequently show concomitant myxoid and squamous features and have high PD‐L1 expression

open access: yesHistopathology, EarlyView.
Aims NFE2L2 encodes the transcription factor, NRF2, which is a regulator of cellular oxidative stress responses and metabolic homeostasis. NFE2L2 alterations are implicated in multiple cancers, with significant study in thoracic oncology, with an adverse prognosis, aggressive behaviour, metabolic reprogramming and diminished responses to chemotherapy ...
Dane Wuori   +5 more
wiley   +1 more source

Re-refinement of the structure of the planar hexagonal phase of ZnO nanocrystals. [PDF]

open access: yesActa Crystallogr B Struct Sci Cryst Eng Mater
The planar hexagonal phase of ZnO is significant for understanding ferroelectricity in this class of materials, and it is well established for ZnO in layered systems. Previously it has been reported as freestanding nanocrystals, but the fitted unit‐cell parameters differed from predictions by up to 16%; we resolve this anomaly to provide fundamental ...
Li M, Zhang L, Ren W, Reimers JR.
europepmc   +2 more sources

Cutaneous Leiomyosarcoma of the Skin: An Updated Review of Epidemiology, Pathogenesis, and Management

open access: yesInternational Journal of Dermatology, EarlyView.
This review provides an update on the epidemiology, pathogenesis, and clinical/histologic features of cutaneous leiomyosarcoma. Prognostic factors (e.g., depth of tumor involvement, grade, etc.) that can facilitate risk stratification are also discussed, as are treatment approaches for this rare malignancy.
Tejas P. Joshi   +4 more
wiley   +1 more source

Reconstruction of native cellular microanatomy in a novel bioengineered full thickness human nasal mucosal construct

open access: yesJournal of Anatomy, EarlyView.
Bioengineered tissue constructs are vital technologies employed in in vitro testing of both fundamental biological principles and industrial screening practices. Current approaches to modelling the nasal mucosa in vitro are not representative and are associated with limitations that impact their reliability and predictive value.
Steven Bradbury   +5 more
wiley   +1 more source

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