Hepatitis C virus p7 protein is crucial for assembly and release of infectious virions. [PDF]
PLoS Pathogens, 2007 Hepatitis C virus (HCV) infection is associated with chronic liver disease and currently affects about 3% of the world population. Although much has been learned about the function of individual viral proteins, the role of the HCV p7 protein in virus ...
Eike Steinmann +5 more
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Classical Swine Fever Virus p7 Protein Interacts with Host Protein CAMLG and Regulates Calcium Permeability at the Endoplasmic Reticulum [PDF]
Viruses, 2018 We have previously shown that Classical Swine Fever Virus (CSFV) p7 is an essential nonstructural protein with a viroporin activity, a critical function in the progression of virus infection. We also identified p7 domains and amino acid residues critical
Douglas P. Gladue +8 more
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PLoS Pathogens, 2015 The hepatitis C virus (HCV) p7 protein is required for infectious virus production via its role in assembly and ion channel activity. Although NMR structures of p7 have been reported, the location of secondary structural elements and orientation of the ...
Margaret A Scull +8 more
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Overexpression of rice black-streaked dwarf virus p7-1 in Arabidopsis results in male sterility due to non-dehiscent anthers. [PDF]
PLoS ONE, 2013 Rice black-streaked dwarf virus (RBSDV), a member of the genus Fijivirus in the family Reoviridae, is propagatively transmitted by the small brown planthopper (Laodelphax striatellus Fallén).
Feng Sun +5 more
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The amino-terminus of the hepatitis C virus (HCV) p7 viroporin and its cleavage from glycoprotein E2-p7 precursor determine specific infectivity and secretion levels of HCV particle types. [PDF]
PLoS Pathogens, 2017 Viroporins are small transmembrane proteins with ion channel activities modulating properties of intracellular membranes that have diverse proviral functions.
Solène Denolly +7 more
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Scientific ReportsClassical swine fever virus (CSFV) p7 viroporin plays crucial roles in cellular ion balance and permeabilization. The antiviral drug amantadine effectively inhibits viral replication by blocking the activity of CSFV p7 viroporin.
Xiaowei Chen, Xiao Wang
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Recognition of tumor-targeting peptide P7 related to the expression level of Hsp90 [PDF]
Jichu yixue yu linchuang, 2021 Objective To analyze the correlation between the expression of heat shock protein 90 (Hsp90) and the recognition of LPLTPLP (P7) on different tumor tissues and para-carcinoma tissues. Methods The expression of HSP90 and recognition effects of FITC-P7
KONG De-xin, HUANG Wei, YANG Nan, LIU Yan-yong
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Molecular dynamics simulations of p7 and HAp7 in the membrane environment.
, 2022 (A) Snapshots represent the position of the p7/TM1/helix-1 structure along the simulation time (50 ns) for p7 and p7(KRAA) structures based on gt1b J4 p7 (PDB ID: 2MTS) and HAp7 structures based on J4 FLAGp7 (PDB ID: 3ZD0).
Nabeel Alzahrani (12055326) +5 more
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, 2022 The five different potential structures of the signal sequence-fused p7 (A) without and (B) with HA-epitope tag at p7 N-terminus, SS-p7 and SS-HAp7, respectively, predicted by the Robetta server [http://robetta.bakerlab.org [47]].
Nabeel Alzahrani (12055326) +5 more
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Rice black streaked dwarf virus P7-2 forms a SCF complex through binding to Oryza sativa SKP1-like proteins, and interacts with GID2 involved in the gibberellin pathway. [PDF]
PLoS ONE, 2017 As a core subunit of the SCF complex that promotes protein degradation through the 26S proteasome, S-phase kinase-associated protein 1 (SKP1) plays important roles in multiple cellular processes in eukaryotes, including gibberellin (GA), jasmonate ...
Tao Tao +14 more
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