Results 101 to 110 of about 10,177 (244)
Brain and Behavior, Volume 15, Issue 1, January 2025.Meta‐analysis of mean plasma levels of BDNF. ABSTRACT Background This systematic review and meta‐analysis evaluates peripheral and CNS BDNF levels in glioma patients. Methods Following PRISMA guidelines, we systematically searched databases for studies measuring BDNF in glioma patients and controls.
Fatemeh Hasani +5 more
wiley +1 more source
Food Science &Nutrition, Volume 13, Issue 1, January 2025.This study demonstrated lycopene could alleviate depression‐like behavior in chronic social defeat stress‐induced mice by promoting synaptic plasticity via the BDNF–TrkB pathway. ABSTRACT Lycopene is a natural plant extract widely studied for its powerful antioxidant and neuroprotective effects.
Heyan Xu +10 more
wiley +1 more source
Human immunomodulatory ligand B7-1 mediates synaptic remodeling via the p75 neurotrophin receptor
The Journal of Clinical Investigation, 2022 Cell surface receptors, ligands, and adhesion molecules underlie development, circuit formation, and synaptic function of the central nervous system and represent important therapeutic targets for many neuropathologies.
Nicholas C. Morano +14 more
doaj +1 more source
Proteoglycan Research, Volume 3, Issue 1, January-March 2025.ABSTRACT Solid tumors present a formidable challenge in oncology, necessitating innovative approaches to improve therapeutic outcomes. Proteoglycans, multifaceted molecules within the tumor microenvironment, have garnered attention due to their diverse roles in cancer progression.
Simone Buraschi +3 more
wiley +1 more source
Schwann Cell Apoptosis and p75NTR siRNA
Iranian Journal of Allergy, Asthma and Immunology, 2011 The p75 pan-neurotrophin receptor (p75NTR) plays a pivotal role in linking the immune system with the nervous system. p75NTR is required for the development of several characteristic features of allergic asthma.
Masoumeh Firouzi +5 more
doaj
Cell Death and Disease, 2019 MAG (Myelin-associated glycoprotein) is a type I transmembrane glycoprotein expressed by Schwann cells and oligodendrocytes, that has been implicated in the control of axonal growth in many neuronal populations including cerebellar granule neurons (CGNs).
D. Fernández-Suárez +4 more
semanticscholar +1 more source
The p75 Neurotrophin Receptor Facilitates TrkB Signaling and Function in Rat Hippocampal Neurons
Frontiers in Cellular Neuroscience, 2019 Neurotrophins activate Trk receptor signaling to support neuronal survival and many aspects of neuronal function. Early studies demonstrated that TrkA formed a complex with the p75 neurotrophin receptor (p75NTR), which increased the affinity and ...
Juan P. Zanin +3 more
doaj +1 more source
Glia, 2018 Neurotrophins mediate neuronal growth, differentiation, and survival via tropomyosin receptor kinase (Trk) or p75 neurotrophin receptor (p75NTR) signaling.
H. P. Düsedau +9 more
semanticscholar +1 more source
p75NTR receptor – role in cell growth and apoptosis
Postępy Higieny i Medycyny Doświadczalnej, 2012 The neurotrophins play an important role in the development of the nervous system. These trophic factors affect the cells through the neurotrophin receptors Trk and p75NTR. Trk (tyrosine kinase receptor) mediated signaling promotes survival and growth, while p75NTR-mediated signaling promotes cell death.
openaire +3 more sources
Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception
Journal of Neuroscience, 2018 Nerve growth factor (NGF) exerts multiple functions on target neurons throughout development. The recent discovery of a point mutation leading to a change from arginine to tryptophan at residue 100 in the mature NGFβ sequence (NGFR100W) in patients with ...
Kijung Sung +13 more
semanticscholar +1 more source