Results 161 to 170 of about 9,698 (210)

p75NTR Modulation by LM11A-31 Counteracts Oxidative Stress and Cholesterol Dysmetabolism in a Rotenone-Induced Cell Model of Parkinson's Disease. [PDF]

Neurochem Res
Pensabene D, Martella N, Scavo G, Bisesto E, Cavicchia F, Colardo M, Varone M, Moreno S, Segatto M.   +8 more
europepmc   +1 more source

Transcriptional Profiling of Botulinum Neurotoxin Type A-Related Molecular Components in Primary Human Schwann Cells. [PDF]

Toxins (Basel)
Sánchez-Carranza O, Jatzke C, Gravius A, Nagel J.   +3 more
europepmc   +1 more source

Nerve Growth Factor in Diabetes Mellitus: Pathophysiological Mechanisms, Biomarkers and Therapeutic Opportunities. [PDF]

Pharmaceuticals (Basel)
Massimino M, Rubino M, Natale MR, Salerno L, Belviso S, Mancuso E, Dagostino A, Demasi D, Barreca F, Averta C, Palummo A, Mannino GC, Andreozzi F.   +12 more
europepmc   +1 more source

Roles of glial p75NTR in axonal regeneration

Journal of Neuroscience Research, 2007
AbstractThe neurotrophin receptor p75 (p75NTR) is expressed by both neurons and glia. Nerve injury triggers up‐regulation of p75NTR in Schwann cells (SC) but not in central glia. In contrast to neuronal p75NTR, which mediates negative signals from myelin‐associated proteins resulting in neurite collapse, glial p75NTR may play a positive role in nerve ...
Xiaofang Zhou, Hongyun Li
exaly   +5 more sources

Astrocytic p75NTR expression provoked by ischemic stroke exacerbates the blood–brain barrier disruption [PDF]

Glia, 2022
The disruption of the blood–brain barrier (BBB) plays a critical role in the pathology of ischemic stroke. p75 neurotrophin receptor (p75NTR) contributes to the disruption of the blood-retinal barrier in retinal ischemia.
Wenhui Huang, Hong Liao, Lv Qunyu
exaly   +3 more sources

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Roles of p75NTR in Maintaining Brain Hemostasis and the Implications for p75NTR-targeted Therapies

Current Alzheimer Research, 2017
The p75 neurotrophin receptor (p75NTR) is a single membrane-spanning receptor in the tumor necrosis factor (TNF) death domain containing receptor family. p75NTR has multiple faces of biological or pathogenic functions by partnering with the three major neurotrophin receptors, including tropomyosin receptor kinase (Trk), sortilin and Nogo receptors.
Jingcheng Li, Huadong Zhou, Yan-Jiang Wang   +2 more
exaly   +3 more sources

The function of p75NTR in glia

Trends in Neurosciences, 2008
The p75 neurotrophin receptor (p75(NTR)) is expressed on many cell types and can influence a variety of cellular functions. This receptor can mediate cell survival or cell death, can promote or inhibit axonal growth and can facilitate or attenuate proliferation, depending on the cell context.
Andrea B, Cragnolini, Wilma J, Friedman
openaire   +2 more sources

p75NTR – live or let die

Current Opinion in Neurobiology, 2005
During neuronal development, neurotrophins are essential factors that promote survival, differentiation and myelination of neurons. The trophic signals are relayed to the cells via binding to Trk receptor tyrosine kinases and the p75 neurotrophin receptor.
Anders, Nykjaer, Thomas E, Willnow, Claus Munck, Petersen   +2 more
openaire   +2 more sources

RanBPM is a novel binding protein for p75NTR

Biochemical and Biophysical Research Communications, 2003
The neurotrophin receptor p75NTR can induce signal transduction both in vivo and in vitro. The mechanisms by which p75NTR transduces signals have remained mostly unknown. Using yeast two-hybrid system, we identified the Ran-binding protein (RanBPM) as an interactor with the intracytoplasmic domain of p75NTR (p75ICD).
Dong, Bai, Hong, Chen, Bing-Ren, Huang
exaly   +3 more sources