DiBELLA: Distributed long read to long read alignment [PDF]
, 2019 We present a parallel algorithm and scalable implementation for genome analysis, specifically the problem of finding overlaps and alignments for data from "third generation" long read sequencers [29]. While long sequences of DNA offer enormous advantages
Buluç, A +4 more
core +2 more sources
Brownotate, a Comprehensive Solution to Generate Protein Sequence Databases for Any Species
PROTEOMICS, EarlyView.ABSTRACT Proteomics is strengthening research in biology and the diversification of the model organisms studied is very promising for fully understanding the complexity of biological principles. However, the lack of protein sequence databases for many species is a major bottleneck.
Adrien Brown +4 more
wiley +1 more source
Complete mitochondrial genome sequence of the freshwater diatom Asterionella formosa
Mitochondrial DNA. Part B. Resources, 2017 We report the complete mitochondrial genome sequence of the freshwater diatom Asterionella formosa. The large 61.9 kb circular sequence encodes 34 proteins and 25 tRNAs that are universally conserved in other sequenced diatoms. We fully resolved a unique
Adrien Villain +11 more
doaj +1 more source
SVIM: Structural Variant Identification using Mapped Long Reads
, 2019 Motivation: Structural variants are defined as genomic variants larger than 50bp. They have been shown to affect more bases in any given genome than SNPs or small indels. Additionally, they have great impact on human phenotype and diversity and have been
Heller, D., Vingron, M.
core +1 more source
Draft Genome Sequences of Strains TAV3 and TAV4 (Verrucomicrobia: Opitutaceae), Isolated from a Wood-Feeding Termite, and In Silico Analysis of Their Polysaccharide-Degrading Enzymes. [PDF]
, 2020 Here, we report the high-quality draft genome sequences of Opitutaceae sp. strains TAV3 and TAV4, which were isolated from the hindgut of the wood-feeding termite Reticulitermes flavipes Using a combination of Illumina and PacBio sequencing, we ...
Isanapong, Jantiya +3 more
core +1 more source
Incorporating soil biological and functional attributes to advance ecological restoration
PLANTS, PEOPLE, PLANET, EarlyView.Earth is currently experiencing a mass extinction crisis, predominantly driven by anthropogenic activities, with land use change causing widespread loss and degradation of native ecosystems and indigenous species. There is an urgent need to halt this trend and restore degraded habitat to preserve biodiversity and protect threatened plants and animals ...
Uffe N. Nielsen +3 more
wiley +1 more source
BMC Bioinformatics, 2018 Background PacBio sequencing platform offers longer read lengths than the second-generation sequencing technologies. It has revolutionized de novo genome assembly and enabled the automated reconstruction of reference-quality genomes. Due to its extremely
Ze-Gang Wei, Shao-Wu Zhang
doaj +1 more source
Engineering compact Physalis peruviana (goldenberry) to promote its potential as a global crop
PLANTS, PEOPLE, PLANET, EarlyView.Goldenberry (Physalis peruviana) produces sweet, nutritionally rich berries, yet like many minor crops, is cultivated in limited geographical regions and has not been a focus of breeding programs for trait enhancement. Leveraging knowledge of plant architecture‐related traits from related species, we used CRISPR/Cas9‐mediated gene editing to generate a
Miguel Santo Domingo +8 more
wiley +1 more source
P472: Highly scalable pharmacogenomic panel testing with hybrid capture and long-read sequencing*
Genetics in Medicine Open, 2023 Nina Gonzaludo +9 more
doaj +1 more source