Results 61 to 70 of about 47,490 (285)
Advanced Science, EarlyView.This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li +9 more
wiley +1 more source
IPA assembly for Hifi PacBio reads v1
, 2021 This protocol is regarding the assembly of plant genomes using HiFi data (PacBio Sequel II) using Improved Phase Assembly (IPA) tool.
Ardashir Kharabian Masouleh +2 more
openaire +1 more source
Advanced Science, EarlyView.Dimethylsulfoniopropionate (DMSP) is a major marine organosulfur compound central to climate‐relevant dimethyl sulfide (DMS) production. In Halomonas sp. D47, DMSP catabolism is revealed to be coordinated by two transcriptional regulators, AcuR and AcuZ, which control gene expression by sensing DMSP and its metabolites.
Li‐Yuan Zheng +16 more
wiley +1 more source
cuteHap: Haplotype‐Aware Structural Variant Detection in Phased Long‐Read Sequencing Data
Advanced Science, EarlyView.cuteHap is a haplotype‐aware structural variant detection method designed for phased long‐read sequencing. By employing self‐adaptive clustering and credibility‐prioritized beam search algorithms, cuteHap generates accurate haplotype‐resolved calls and outperforms state‐of‐the‐art tools.
Shuqi Cao +7 more
wiley +1 more source
PacBio Isoseq samples preparation v1
, 2023 This protocol described how to prepare samples for PacBio Isoseq
openaire +1 more source
Comprehensive analysis of structural variants in chickens using PacBio sequencing
Frontiers in Genetics, 2022 Structural variants (SVs) are one of the main sources of genetic variants and have a greater impact on phenotype evolution, disease susceptibility, and environmental adaptations than single nucleotide polymorphisms (SNPs). However, SVs remain challenging to accurately type, with several detection methods showing different limitations. Here, we explored
Jinxin Zhang +16 more
openaire +3 more sources
Circlator: automated circularization of genome assemblies using long sequencing reads [PDF]
, 2015 The assembly of DNA sequence data is undergoing a renaissance thanks to emerging technologies capable of producing reads tens of kilobases long.
Harris, Simon R. +5 more
core +3 more sources
Advanced Science, EarlyView.This study firstly presents a comprehensive and high‐resolution pan‐3D genome resource in chicken. Our findings reveal the role of structural variations in 3D genome architectures, and how they influence the domestication process and production traits at the 3D genome level.
Zhen Zhou +19 more
wiley +1 more source
The complete mitochondrial genome of the tartar Sand Boa Eryx tataricus
Mitochondrial DNA. Part B. Resources, 2019 Eryx is a genus of snakes belonging to the family Boidae. In this study, the mitochondrial genome sequence of Eryx tataricus was generated using a PacBio RSII DNA sequencer employing the single molecule, real-time sequencing technology.
Xiuli Sun, Yaping Li, Jia Liu, Jun Sheng
doaj +1 more source
AlignGraph2: similar genome-assisted reassembly pipeline for PacBio long reads
Briefings in Bioinformatics, 2021 Abstract Contigs assembled from the third-generation sequencing long reads are usually more complete than the second-generation short reads. However, the current algorithms still have difficulty in assembling the long reads into the ideal complete and accurate genome, or the theoretical best result [1].
Shien, Huang +3 more
openaire +2 more sources