Results 71 to 80 of about 47,490 (285)

Whole-genome sequencing of Klebsiella pneumoniae isolates to track strain progression in a single patient with recurrent urinary tract infection [PDF]

, 2019
Klebsiella pneumoniae is an important uropathogen that increasingly harbors broad-spectrum antibiotic resistance determinants. Evidence suggests that some same-strain recurrences in women with frequent urinary tract infections (UTIs) may emanate from a ...
Minx, Patrick J, Rosen, David A, Wylie, Kristine M, Wylie, Todd N   +3 more
core   +5 more sources

A Scalable Framework for Comprehensive Typing of Polymorphic Immune Genes from Long‐Read Data

Advanced Science, EarlyView.
SpecImmune introduces a unified computational framework optimized for long‐read sequencing to resolve over 400 highly polymorphic immune genes. This scalable approach achieves high‐resolution typing, enabling the discovery of cross‐family co‐evolutionary networks and population‐specific diversity.
Shuai Wang, Xuedong Wang, Mengyao Wang, Qian Zhou, Lusheng Wang, Shuai Cheng Li   +5 more
wiley   +1 more source

Multi‐Targeting Non‐Specific Genome Engineering in Bacteria

Advanced Science, EarlyView.
In this study, we provide the first case to use the multi‐targeting integrase (MTI) systems in bacteria and develop a host‐independent generalizable approach, MNGE (Multi‐targeting Non‐specific Genome Engineering), for multi‐copy and random integration of metabolic genes or pathways in both Gram‐positive and Gram‐negative bacteria, which will ...
Runze Sun, Ruixiang You, Yiwen Zhou, Huiyan He, Wenfang Wang, Xudong Qu, Yinhua Lu, Lei Li   +7 more
wiley   +1 more source

Caracterización de las tecnologías de secuenciación genética de segunda y tercera generación

Tecnología en Marcha
El avance en la secuenciación de material genético ha favorecido el estudio de nuevas áreas de investigación relacionadas a la genómica, transcriptómica y demás ciencias -ómicas.
Dorian Rojas-Villalta, Daniela Benavides-Villegas, Belén Angulo-Hidalgo, Luis Muñoz-Solorzano, Chiara Consumi-Tubito   +4 more
doaj   +1 more source

A Murine Database of Structural Variants Identifies A Candidate Gene for a Spontaneous Murine Lymphoma Model

Advanced Science, EarlyView.
We analyzed long‐read genomic sequencing data obtained from 40 inbred mouse strains to produce a large database of structural variants. This dataset captures the major types of structural variants, which includes deletions, insertions, duplications, and inversions.
Wenlong Ren, Zhuoqing Fang, Egor Dolzhenko, Christopher T. Saunders, Zhuanfen Cheng, Victoria Popic, Gary Peltz   +6 more
wiley   +1 more source

Genome Improvement and Genetic Map Construction for Aethionema arabicum, the First Divergent Branch in the Brassicaceae Family

G3: Genes, Genomes, Genetics, 2019
The genus Aethionema is a sister-group to the core-group of the Brassicaceae family that includes Arabidopsis thaliana and the Brassica crops. Thus, Aethionema is phylogenetically well-placed for the investigation and understanding of genome and trait ...
Thu-Phuong Nguyen, Cornelia Mühlich, Setareh Mohammadin, Erik van den Bergh, Adrian E. Platts, Fabian B. Haas, Stefan A. Rensing, M. Eric Schranz   +7 more
doaj   +1 more source

SMRT-based mitochondrial genome of the edible mushroom Morchella conica

Mitochondrial DNA. Part B. Resources, 2020
Morchella conica Pers. is a highly-prized mushroom for its edible and medical values. In this study, we determined the complete mitochondrial genome of M. conica combining both PacBio and Illumina sequencing technologies.
Wei Li, Fen Zhang, Li-zhi Gao
doaj   +1 more source

The genome sequence of Barbarea vulgaris facilitates the study of ecological biochemistry [PDF]

, 2017
peer-reviewedThe genus Barbarea has emerged as a model for evolution and ecology of plant defense compounds, due to its unusual glucosinolate profile and production of saponins, unique to the Brassicaceae. One species, B.
Agerbirk, Niels, Asp, Torben, Bak, Søren, Byrne, Stephen, Hauser, Thure Pavlo, Nagy, Istvan, Paina, Cristiana, Østerbye Erthmann, Pernille   +7 more
core   +2 more sources

Deciphering the Evolution Pattern of Structural Variations Overlapped With Repetitive Sequence During Cattle Evolution

Advanced Science, EarlyView.
The authors complement bovine pan‐SV with massive novel structural variations (SVs) identified through long‐read sequencing of 83 globally distributed cattle breeds. Repetitive sequence‐mediated SVs (rep‐SV) exhibit distinct dynamic patterns throughout cattle sub‐speciation and/or domestication processes, including uneven distribution between chr‐X and
Zhifan Guo, Jinxiu Li, Adeniyi C. Adeola, Xueyan Jiang, Juntao Ma, Jian Xiao, Dexiang Hu, Kaixing Qu, Haihong Wu, Junren Chen, Zhanxing He, Tingting Yin, Ali Esmailizadeh, Jing Luo, Olivier Hanotte, Ya‐Ping Zhang, Yan Li   +16 more
wiley   +1 more source

Applications and Trends of Machine Learning in Genomics and Phenomics for Next-Generation Breeding

Plants, 2019
Crops are the major source of food supply and raw materials for the processing industry. A balance between crop production and food consumption is continually threatened by plant diseases and adverse environmental conditions. This leads to serious losses
Salvatore Esposito, Domenico Carputo, Teodoro Cardi, Pasquale Tripodi   +3 more
doaj   +1 more source