Results 21 to 30 of about 107,995 (304)
Plasminogen influence on the PAI-1 release by human platelets [PDF]
The Ukrainian Biochemical JournalРАІ-1 (plasminogen activator inhibitor type 1), as a major physiological inhibitor of tissue plasminogen activator and urokinase, plays a key role in the regulation of fibrinolysis in vivo.
O. I. Yusova +3 more
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PAI‐1 and atherothrombosis [PDF]
Journal of Thrombosis and Haemostasis, 2005 Plasminogen activator inhibitor-1 (PAI-1) is the major physiologic inhibitor of tissue-type plasminogen activator in plasma, and is elevated in a variety of clinical situations that are associated with increased risk of ischemic cardiovascular events. Recent insights into the biology of PAI-1 suggest that it is more than just an innocent bystander in ...
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4 open, 2019 The anti-hyperglycemic drug, Metformin, is effective in treating early stages of diabetes and has been associated with a 37% decrease in cancer incidence. While the precise mechanisms for the anti-cancer effects of Metformin remain to be elucidated, this
Brücher Björn L.D.M., Jamall Ijaz S.
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Non-invasive assessment of peritoneal membrane alterations
Bulletin de la Dialyse à Domicile, 2020 The peritoneal dialysis membrane is subject to remodelling in the course of peritoneal dialysis. In the absence of longitudinal morphological studies, this process is mainly studied indirectly by the investigation of changes in peritoneal transport.
Raymond Krediet, Alena Parikova
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Российский кардиологический журнал, 2022 Aim. To determine the features of expression and secretion of plasminogen activator inhibitor-1 (PAI-1) by subcutaneous, epicardial and perivascular adipocytes depending on the complexity of coronary artery disease (CAD).Material and methods.
E. V. Belik +6 more
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Recombinant PAI-1 therapy restores myoendothelial junctions and erectile function in PAI-1-deficient mice [PDF]
Andrologia, 2014 Myoendothelial junctions are specialised projections of cell : cell contact through the internal elastic lamina between endothelial cells and vascular smooth muscle cells. These junctions allow for endothelial cells and vascular smooth muscle cells to make direct membrane apposition and are involved in cell : cell communication.
P K, Kavoussi +9 more
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Multifunctionality of PAI-1 in fibrogenesis: Evidence from obstructive nephropathy in PAI-1–overexpressing mice [PDF]
Kidney International, 2005 Plasminogen activator inhibitor-1 (PAI-1) has been implicated in the pathogenesis of chronic kidney disease based on its up-regulated expression and on the beneficial effects of PAI-1 inhibition or depletion in experimental models. PAI-1 is a multifunctional protein and the mechanisms that account for its profibrotic effects have not been fully ...
Matsuo, Shunya +8 more
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Residual vein thrombosis and onset of post-thrombotic syndrome: Influence of the 4G/5G polymorphism of plasminogen activator inhibitor-1 gene [PDF]
, 2014 BACKGROUND: Plasminogen activator inhibitor-1 (PAI-1) is the most important inhibitor of plasminogen activator. The functional 4G/5G polymorphism of the gene coding for PAI-1 may affect PAI-1 plasmatic activity, influencing the imbalance between ...
Amato, C +6 more
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Turkish Journal of Hematology, 2012 OBJECTIVE: Ankaferd Blood Stopper (ABS) comprises a mixture of the plants Thymus vulgaris, Glycyrrhiza glabra, Vitis vinifera, Alpinia officinarum ve Urtica dioica.
Afife Karabıyık +4 more
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Annals of Indian Academy of Neurology, 2020 Objective: Despite advances made in the treatment of ischemic stroke, it still remains one of the leading causes of mortality and disability worldwide.
Adina Hutanu +4 more
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