Results 51 to 60 of about 1,900,236 (234)
Brazilian Journal of Poultry ScienceThermal manipulation (TM) during broiler chicken embryogenesis has been shown to promote muscle development and growth. However, the molecular bases of promoting broiler muscle development and growth are not fully understood. The aim of this study was to
MB Al-Zghoul +6 more
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IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
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Cancer Pathogenesis and TherapyBackground: Immunotherapy favors patients with tumors; however, only 3–26.3% of patients with cervical cancer benefit from single-agent immune checkpoint inhibitors.
Xue Feng +12 more
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Antigen-specific serum antibody responses.
, 2016 NHC flagellin-specific antibody levels in the groups immunized with (A) 40 μg of NHC protein and (B) 20 μg of NHC protein, both compared to levels in the solvent injected control group.
Jos P. M. van Putten (103913) +5 more
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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular OncologyPaired box protein Pax‐8 (PAX8) is a critical lineage marker and master regulator of transcription in high‐grade serous ovarian carcinoma (HGSC)—the most common subtype of epithelial ovarian cancer—driving cell proliferation and migration and resisting ...
Aya Saleh +12 more
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Advanced Functional Materials, EarlyView.Schematic illustration of the engineered RN@FDT for multimodal tumor therapy. a) Fabrication of FD&DOX/TFA‐loaded RGD‐NNV (RN@FDT) and the light‐triggered disassemble of RN@FDT. b) After internalized by tumor cells, RN@FDT are disintegrated under NIR‐II laser irradiation to boost PTT and induce cell apoptosis.
Jiahui Zhang +16 more
wiley +1 more source
Paired ITE teaching placements: implications for partnership development
, 2009 This paper describes outcomes from a project designed to maximise the potential of paired placements for secondary mathematics ITE students. We explore the development of models for effective pairings and provide the rationale for these models.
Wilson, Paul, Edwards, Julie-Ann
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BMC Veterinary ResearchBackground Cutaneous B-cell lymphoma is extremely rare in dogs; only few cases have been reported in veterinary literature, and its clinicopathological characteristics, biological behavior, and classification remain incompletely characterized.
Yunho Jeong +6 more
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Primary Splenic Mesothelioma: A Rare Entity
Journal of Clinical and Diagnostic ResearchMalignant mesothelioma is a primary neoplasm that arises from the serous membranes lining the pleura, peritoneum, and pericardium. However, mesothelioma arising from the spleen is exceedingly rare and presents unique diagnostic and clinical challenges. A
Monika Kalyan +4 more
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