Results 211 to 220 of about 92,701 (241)

Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review). [PDF]

Mol Med Rep
Zhang S, Li Z, Fu L.
europepmc   +1 more source

Correlation between pathogenic <i>CYP1B1</i> variants and trabeculodysgenesis under ultrasound biomicroscopy in primary congenital glaucoma. [PDF]

Int J Ophthalmol
Gao Y, Lin DT, Zhou T, He LH, Zhao KX, Yu XW, Deng L, Fan ZG, Shi Y.   +8 more
europepmc   +1 more source

Superenhancers shape the landscape and repair dynamics of transcription-associated DNA breaks in cancer. [PDF]

Sci Adv
Hidmi O, Shatleh D, Flayshman SO, Monin J, Aqeilan RI.   +4 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Paired Box (Pax) Transcription Factors and Aging

2020
The age-dependent complex alterations in metabolism of nucleic acids, proteins, and expression of transcription factors have been observed in various models from bacteria to humans. The paired box (Pax) family transcription factors prove essential for development, growth, and differentiation; organogenesis; and maintaining functional anatomy of vital ...
Shashank Maurya, Mishra Rajnikant
exaly   +2 more sources

Serum growth factor regulation of the paired-box transcription factor Pax-3 in neuronal cells

Neuroscience Letters, 1996
Mutations in the murine Pax (paired-box)-3 gene results in a number of developmental abnormalities including a deficiency in sensory neurons. To determine the role that Pax-3 plays in neuronal cell development, we have studied the expression of Pax-3 in the ND7 neuronal cell line. Upon serum starvation, Pax-3 mRNA expression fell rapidly. Within 2 h of
Karen Lillycrop, John Evans, K A Lillycrop   +2 more
exaly   +3 more sources

Genetic Variability of the Paired Box Transcription Factor; PAX8 Gene: Guidance Towards Treatment Strategies in a Cohort of Congenital Hypothyroidism

Hormone and Metabolic Research, 2021
AbstractThe contribution of PAX8 genetic variants to congenital hypothyroidism (CH) is not well understood. We aimed to study the genetic variability of exons 3 and 5 of PAX8 gene among a cohort of children with congenital hypothyroidism in correspondence to their clinical aspect.
Sohier S. Abou El-Ella, Essam Shawky A.E.H. Khattab, Rehab K. Beddah, Naglaa Fathy Barseem   +3 more
openaire   +2 more sources

The paired box transcription factor Pax8 is essential for function and survival of adult thyroid cells

Molecular and Cellular Endocrinology, 2014
The transcription factor Pax8 is already known to be essential at very early stages of mouse thyroid gland development, before the onset of thyroid hormone production. In this paper we show, using a conditional inactivation strategy, that the removal of the Pax8 protein late in gland development results in severe hypothyroidism, consequent to a reduced
Marotta P, Amendola E, Scarfò M, De Luca P, Zoppoli P, AMORESANO, ANGELA, DE FELICE, MARIO, DI LAURO, ROBERTO   +7 more
openaire   +4 more sources

Differential expression of four alternate Pax7 paired box transcripts is influenced by organ- and strain-specific factors in adult mice

Gene, 1998
The developmental paired-type gene Pax7 is expressed in skeletal muscle and brain during development and in the adult mouse. In this study, RNA was isolated from the brains and skeletal muscles of the limbs of adult BALB/c and SJL/J mice to determine whether there were alternate transcripts which could account for the biological diversity of Pax7. Four
M R, Ziman, P H, Kay
openaire   +2 more sources

Analysis of Human Sodium/Iodide Symporter, Thyroid Transcription Factor-1, and Paired-Box-Protein-8 Gene Expression in Benign Thyroid Diseases

Thyroid, 1999
The ability to concentrate iodide, a fundamental property of normally functioning thyroid tissue, is altered in various thyroid diseases. Given the critical role of the Na+/I- symporter (NIS) in controlling iodide access to the thyroid gland, altered expression of NIS may be responsible, at least in part, for an enhanced or diminished capacity to ...
W, Joba, C, Spitzweg, K, Schriever, A E, Heufelder   +3 more
openaire   +2 more sources