Results 221 to 230 of about 92,701 (241)
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Anticancer research, 1998
The bcl-2 proto-oncogene suppresses apoptosis in a variety of cell types and is essential for normal renal development. PAX8 is a member of the paired box class of transcription factors and is developmentally regulated. bcl-2 and PAX8 are both expressed in the kidney during development and throughout life, demonstrating a nearly identical pattern of ...
S M, Hewitt +5 more
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The bcl-2 proto-oncogene suppresses apoptosis in a variety of cell types and is essential for normal renal development. PAX8 is a member of the paired box class of transcription factors and is developmentally regulated. bcl-2 and PAX8 are both expressed in the kidney during development and throughout life, demonstrating a nearly identical pattern of ...
S M, Hewitt +5 more
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British Journal of Haematology, 2003
Summary. Overexpression of the embryonic transcription factor, Wilms’ tumour protein 1 (WT1), is common in acute myeloid leukaemias (AML). Mutations of Wilms’ tumour gene 1 (WT1) in AML are rare and WT1 expression may be increased by other transcription factors. PAX2, PAX8 and GATA‐1 are known physiological regulators of WT1.
Jan M, Siehl +6 more
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Summary. Overexpression of the embryonic transcription factor, Wilms’ tumour protein 1 (WT1), is common in acute myeloid leukaemias (AML). Mutations of Wilms’ tumour gene 1 (WT1) in AML are rare and WT1 expression may be increased by other transcription factors. PAX2, PAX8 and GATA‐1 are known physiological regulators of WT1.
Jan M, Siehl +6 more
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1997
Rhabdomyosarcoma (RMS) is a soft tissue tumor with striated muscle differentiation which usually presents in pediatric patients (Raney et al. 1993). Though histopathologic classification has evolved over time, two major forms of childhood RMS are consistently recognized, embryonal (ERMS) and alveolar (ARMS).
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Rhabdomyosarcoma (RMS) is a soft tissue tumor with striated muscle differentiation which usually presents in pediatric patients (Raney et al. 1993). Though histopathologic classification has evolved over time, two major forms of childhood RMS are consistently recognized, embryonal (ERMS) and alveolar (ARMS).
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Cancer research, 1999
Alveolar rhabdomyosarcoma (ARMS) is an aggressive pediatric soft tissue tumor with striated muscle differentiation. Chromosomal studies of these tumors identified 2;13 and 1;13 translocations. Using physical mapping and cloning strategies, we determined that t(2;13) and t(1;13) rearrange PAX3 and PAX7, which encode members of the paired box ...
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Alveolar rhabdomyosarcoma (ARMS) is an aggressive pediatric soft tissue tumor with striated muscle differentiation. Chromosomal studies of these tumors identified 2;13 and 1;13 translocations. Using physical mapping and cloning strategies, we determined that t(2;13) and t(1;13) rearrange PAX3 and PAX7, which encode members of the paired box ...
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Oncogene, 1996
The Wilms' tumor suppressor gene, wt1, encodes a zinc finger protein which functions as a transcriptional regulator. Expression of the wt1 gene is developmentally regulated and restricted to a small set of tissues which include the fetal urogenital system, mesothelium, and spleen.
M, Dehbi +4 more
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The Wilms' tumor suppressor gene, wt1, encodes a zinc finger protein which functions as a transcriptional regulator. Expression of the wt1 gene is developmentally regulated and restricted to a small set of tissues which include the fetal urogenital system, mesothelium, and spleen.
M, Dehbi +4 more
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Anticancer Research
Both mesonephric adenocarcinoma (MA) and mesonephric-like adenocarcinoma (MLA) express thyroid transcription factor 1 (TTF1). TTF1 is also considered a highly sensitive and specific diagnostic marker for primary lung adenocarcinoma (PLA). However, distinguishing PLA from pulmonary metastatic MA/MLA (PMM) based on the expression of TTF1 alone can be ...
Nayoon, Ji +3 more
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Both mesonephric adenocarcinoma (MA) and mesonephric-like adenocarcinoma (MLA) express thyroid transcription factor 1 (TTF1). TTF1 is also considered a highly sensitive and specific diagnostic marker for primary lung adenocarcinoma (PLA). However, distinguishing PLA from pulmonary metastatic MA/MLA (PMM) based on the expression of TTF1 alone can be ...
Nayoon, Ji +3 more
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Regulation of the paired box transcription factor Pax-3
Biochemical Society Transactions, 1998F, Reeves, R, Harris, K, Lillycrop
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Paired box 8 in organogenesis and oncogenesis – a review
European Journal of Clinical and Experimental Medicine, 2022exaly