Results 61 to 70 of about 2,464 (131)

Effect of palmatine hydrochloride on cognitive dysfunction in streptozotocin-induced diabetic Rats

مجله دانشگاه علوم پزشکی گرگان, 2013
Background and Objective: Recent studies have shown that diabetes induced cognitive dysfunction and impairs learning and memory. Palmatine is an isoquinoline alkaloid, and has multiple pharmacological effects, including anti-diabetic and antioxidant ...
Ahouei M, Vaezi Gh, Kalalian Moghaddam H, Alamalhoda F   +3 more
doaj  

Screening and evaluation of metabolites binding PRAS40 from Erxian decoction used to treat spinal cord injury

Frontiers in Pharmacology
Objective: The PRAS40 is an essential inhibitory subunit of the mTORC1 complex, which regulates autophagy. It has been suggested that Erxian Decoction (EXD) could treat spinal cord injury (SCI) via the autophagy pathway. However, the mechanism of whether
Li Lin, Jingchuan Yan, Jin Sun, Jianfeng Zhang, Bo Liao   +4 more
doaj   +1 more source

Strong Synergism of Palmatine and Fluconazole/Itraconazole Against Planktonic and Biofilm Cells of Candida Species and Efflux-Associated Antifungal Mechanism

Frontiers in Microbiology, 2018
Fungal infections caused by Candida albicans and non-albicans Candida [NAC] species are becoming a growing threat in immunodeficient population, people with long-term antibiotic treatment and patients enduring kinds of catheter intervention.
Tianming Wang, Jing Shao, Wenyue Da, Qianqian Li, Gaoxiang Shi, Daqiang Wu, Changzhong Wang   +6 more
doaj   +1 more source

Berberrubine inhibits Helicobacter pylori by inducing oxidative stress and impairing membrane integrity

mLife, Volume 5, Issue 1, Page 126-130, February 2026.
Minzhi Jiang, Changyu Wang, Kai Wang, Xinchi Feng, Gen Li, Yu Jiang, Xue Wang, Shijie Cao, Liqin Ding, Shuangyu Bi, Feng Qiu, Shuang‐Jiang Liu, Chang Liu   +12 more
wiley   +1 more source

Extracts from Traditional Chinese Medicinal Plants Inhibit Acetylcholinesterase, a Known Alzheimer’s Disease Target

Molecules, 2016
Inhibition of acetylcholinesterase (AChE) is a common treatment for early stages of the most general form of dementia, Alzheimer’s Disease (AD). In this study, methanol, dichloromethane and aqueous crude extracts from 80 Traditional Chinese Medical (TCM)
Dorothea Kaufmann, Anudeep Kaur Dogra, Ahmad Tahrani, Florian Herrmann, Michael Wink   +4 more
doaj   +1 more source

Palmatine chloride inhibits

Ecotoxicology and Environmental Safety
Harmful cyanobacterial blooms threaten aquatic ecosystems and public health through cyanotoxin release and oxygen depletion. This study evaluated the inhibitory activity of palmatine chloride (PC) against Microcystis aeruginosa under different light and ...
Xuemei Chen, Xueying Fan, Ping Zhang, Caihong Qin, Kai Li, Bingbing Qin, Junlei Wang, Hongqing Li, Yan Xiao   +8 more
doaj   +1 more source

Antioxidant and cytotoxic activities of Thai medicinal plants named Khaminkhruea: Arcangelisia flava, Coscinium blumeanum and Fibraurea tinctoria [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2005
The stems of Arcangelisia flava, Coscinium blumeanum and Fibraurea tinctoria, collectively known in southern Thailand as Khaminkhruea, were sequentially extracted with petroleum ether, chloroform, methanol, and boiling water to afford 12 crude extracts ...
Niwat Keawpradub, Sukanya Dej-adisai, Supreeya Yuenyongsawad   +2 more
doaj  

Isolation and Quantification of Palmatine from Fibraurea tinctoria Lour: In Vitro Antioxidant Activity and In Silico Antidiabetic Activity Evaluation

Drug Design, Development and Therapy
Indah Purwaningsih,1,2 Iman Permana Maksum,1 Dadan Sumiarsa,1 Sriwidodo Sriwidodo3 1Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Padjadjaran, Sumedang, 45363, Indonesia; 2Department of Medical Laboratory Technology ...
Purwaningsih I, Maksum IP, Sumiarsa D, Sriwidodo S   +3 more
doaj  

PREPARATIVE SEPARATION OF ISOQUINOLINE ALKALOIDS FROM PHELLODENDRI CORTEX BY PH-ZONE-REFINING COUNTER-CURRENT CHROMATOGRAPHY

Química Nova
pH-Zone-refining counter-current chromatography (PZRCCC) was successfully used for preparative separation isoquinoline alkaloids from Phellodendri Cortex.
Daijie Wang, Shanming Tian, Li Cui, Huijiao Yan, Xiangyun Song, Yuguo Liu, Fei Xu, Junjian Ma   +7 more
doaj   +1 more source

Palmatine-Intercalated Montmorillonite Improves Intestinal Health and Attenuates Systemic Inflammation in ETEC-Challenged Piglets. [PDF]

Animals (Basel)
Gan L, Zhao Y, Li S, Sheng Y, Zhao D, Yuan Y, Qiao H, Wang P, Duan E, Liu T, Wang J.   +10 more
europepmc   +1 more source