Results 61 to 70 of about 2,409 (171)

The Role of Gut Microbiota in Fish Viral Infection: Mechanisms and Microbiota‐Targeted Interventions

open access: yesAquaculture Nutrition, Volume 2026, Issue 1, 2026.
Viral diseases represent one of the major threats to the global aquaculture industry. In recent years, the relationship between gut microbiota and viral infections in fish has garnered increasing attention. The gut microbiota contributes critically to fish health and is involved in antiviral defense through immune regulation, secretion of microbial ...
Qiong Zhao   +4 more
wiley   +1 more source

Comprehensive Experimental and Computational Characterization of a Phenylacetamide‐Based Molecule

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
The aim of this study was to synthesize Tetrahydroisoquinoline Derivative 1 (M1) and to evaluate its biological activities in the SH‐SY5Y neuroblastoma cell line. Theoretical calculations for the investigated molecule were performed using the Gaussian software package at the B3LYP, HF, and M062X levels with the 6‐31g, 6‐31++g, and 6‐31++g(d,p) basis ...
Tugba Agbektas   +10 more
wiley   +1 more source

Role of Chinese Botanical Drugs in the Adjuvant Treatment of Helicobacter pylori Infection: An Umbrella Review of the Evidence of Randomized Controlled Trials

open access: yesInternational Journal of Clinical Practice, Volume 2026, Issue 1, 2026.
Aim To evaluate the quality of evidence, potential biases, and validity of all available meta‐analyses about the Chinese botanical drug treatment for the Helicobacter pylori (Hp) infection. Materials and Methods A comprehensive search of six electronic databases (PubMed, Embase, Web of Science, Cochrane Database of Systematic Reviews, CNKI, Wanfang ...
Yuege Yang   +5 more
wiley   +1 more source

The underlying mechanism of modified palmatine for calcified cells

open access: yes四川大学学报. 自然科学版, 2018
To explore the role of palmatine in vascular calcification,we employed a calcific cell model using β-glyceophosphate to stimulate the rat aortic smooth muscle cells (RASMCs).
QIAO Jie   +5 more
doaj  

Anti-Acetylcholinesterase Activities of Mono-Herbal Extracts and Exhibited Synergistic Effects of the Phytoconstituents: A Biochemical and Computational Study

open access: yesMolecules, 2019
Alzheimer’s disease (AD), a neurodegenerative disease, is the most common form of dementia. Inhibition of acetylcholinesterase (AChE) is a common strategy for the treatment of AD. In this study, aqueous, hydro-methanolic, and methanolic extracts of
Acharya Balkrishna   +7 more
doaj   +1 more source

Experimental Study of YaJieShaBa Antialcoholic Hepatic Fibrosis Through TGF‐β1/Smad Signaling Pathway

open access: yesMediators of Inflammation, Volume 2026, Issue 1, 2026.
Objective This study aimed to clarify the pharmacodynamic effects of YaJieShaBa (YJSB) against alcoholic hepatic fibrosis (HF) and elucidate its mechanism in regulating the transforming growth factor‐β1 (TGF‐β1)/Smad pathway. Methods Induce the alcoholic HF model in rats using 56% ethanol (10 mL/kg).
Linao Zhang   +10 more
wiley   +1 more source

Palmatine Is a Plasmid-Mediated Quinolone Resistance (PMQR) Inhibitor That Restores the Activity of Ciprofloxacin Against QnrS and AAC(6ʹ)-Ib-cr-Producing Escherichia coli

open access: yesInfection and Drug Resistance, 2020
Peng Wang, 1 Longfei Hu, 1 Zhihui Hao 2 1Agricultural Bio-Pharmaceutical Laboratory, Qingdao Agricultural University, Qingdao 266109, People’s Republic of China; 2National Centre for Veterinary Drug Safety Evaluation, College of Veterinary ...
Wang P, Hu L, Hao Z
doaj  

ATOJIN: A Natural Products Mixture, Alleviates Atopic Dermatitis in DNCB‐Induced NC/Nga Mice

open access: yesMediators of Inflammation, Volume 2026, Issue 1, 2026.
Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder with increasing global prevalence. ATOJIN is a natural product composed of Phellodendron amurense Ruprecht (PAR), Schizonepeta tenuifolia (ST), Sophora flavescens (SF), Glycyrrhiza uralensis (GU), and Liriope platyphylla (LP), all known for their anti‐inflammatory properties ...
Sang-Eun Lee   +5 more
wiley   +1 more source

Effect of palmatine hydrochloride on cognitive dysfunction in streptozotocin-induced diabetic Rats

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2013
Background and Objective: Recent studies have shown that diabetes induced cognitive dysfunction and impairs learning and memory. Palmatine is an isoquinoline alkaloid, and has multiple pharmacological effects, including anti-diabetic and antioxidant ...
Ahouei M   +3 more
doaj  

Berberrubine inhibits Helicobacter pylori by inducing oxidative stress and impairing membrane integrity

open access: yes
mLife, Volume 5, Issue 1, Page 126-130, February 2026.
Minzhi Jiang   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy