Results 41 to 50 of about 2,464 (131)

Encephalopathy: Cause, Pathogenesis, and Treatment

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv   +7 more
wiley   +1 more source

Effect of palmatine hydrochloride on testicular damage in streptozotocin-induced diabetic rats

open access: yesThe Journal of Qazvin University of Medical Sciences, 2017
Background: Diabetes mellitus mediated by oxidative stress, creates serious metabolic disorders in testis. Palmatine hydrochloride has various pharmacological effects, including anti-diabetic and antioxidant activities.
P. Norouzi   +3 more
doaj  

Palmatine as an Agent Against Metabolic Syndrome and Its Related Complications: A Review

open access: yesDrug Design, Development and Therapy, 2020
Sophia Ogechi Ekeuku,1 Kok-Lun Pang,1 Kok-Yong Chin1,2 1Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia; 2State Key Laboratory of Oncogenes and Related Genes, Renji-Med X Clinical Stem Cell ...
Ekeuku SO, Pang KL, Chin KY
doaj  

Rhodium-Catalyzed Ortho-Vinylation of 2-Arylpyridines and Its Application in the Total Synthesis of Palmatine

open access: yesPharmaceutical Fronts, 2020
An efficient protocol by Rh-catalyzed direct C–H vinylation of 2-arylpyridines with a commercially available and air-stable potassium vinyl donor has been developed.
Shan Lv   +6 more
doaj   +1 more source

Biodegradable Sodium Alginate Films Incorporated With Jateorhiza palmata (Lam.) Miers Extract for Active Food Packaging

open access: yesPackaging Technology and Science, Volume 39, Issue 4, Page 367-382, April 2026.
Development of biodegradable sodium alginate films incorporated with J. palmata root extracts showing enhanced antioxidant and functional properties for active food packaging applications. ABSTRACT Biodegradable packaging helps reduce environmental impact by decomposing naturally and preventing plastic accumulation in ecosystems.
Carlos Augusto Badillo Almeira   +4 more
wiley   +1 more source

Electrokinetic Manipulations Combined With Direct and Ambient Ionization Mass Spectrometry

open access: yesMass Spectrometry Reviews, Volume 45, Issue 2, Page 244-259, March/April 2026.
ABSTRACT Mass spectrometry (MS) is a powerful analytical technique that typically involves sample preparation and online analytical separation before MS detection. Traditional methods often face bottlenecks in sample preparation and analytical separation, despite the rapid detection capabilities of MS.
Nicholas E. Manicke   +2 more
wiley   +1 more source

Optimization of Deep Eutectic Solvents Extraction of Effective Components from Phellodendron chinense Schneid by Response Surface Methodology

open access: yesInternational Journal of Chemical Engineering, 2022
Taking Phellodendron chinense Schneid (PcS) as the raw material with ultrasonic-assisted eutectic solvent, the effects of various DESs on the extractable content of palmatine and berberine in PcS were investigated. On the basis of the single-factor test,
Xianwen Yue   +4 more
doaj   +1 more source

Spatial heterogeneity in microglia‐complement crosstalk: Implications for synaptic pruning in Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract Alzheimer's disease (AD) is a neurodegenerative disorder characterized by synaptic loss, as a key pathological feature in its early stages. Recent studies have highlighted the central role of microglia–complement interactions in synaptic pruning.
Qiuyan Ye   +10 more
wiley   +1 more source

Synthesis of a water-soluble 2,2′-biphen[4]arene and its efficient complexation and sensitive fluorescence enhancement towards palmatine and berberine

open access: yesBeilstein Journal of Organic Chemistry, 2018
A water-soluble 2,2′-biphen[4]arene (2,2’-CBP4) containing eight carboxylato moieties was synthesized and characterized. Its complexation behavior towards two alkaloids, palmatine (P) and berberine (B), was investigated by means of fluorescence and 1H ...
Xiayang Huang   +5 more
doaj   +1 more source

Palmatine from Unexplored Rutidea parviflora Showed Cytotoxicity and Induction of Apoptosis in Human Ovarian Cancer Cells

open access: yesToxins, 2019
Ovarian cancer ranks amongst the deadliest cancers in the gynaecological category of cancers. This research work aims to evaluate in vitro anti-ovarian cancer activities and identify phytochemical constituents of a rarely explored plant species— ...
Okiemute Rosa Johnson-Ajinwo   +2 more
doaj   +1 more source

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