Results 51 to 60 of about 2,464 (131)

Synthesis and Structure–Activity Relationship of Palmatine Derivatives as a Novel Class of Antibacterial Agents against Helicobacter pylori

Molecules, 2020
Taking palmatine (PMT) as the lead, 20 new PMT derivatives were synthesized and examined for their antibacterial activities against six tested metronidazole (MTZ)-resistant Helicobacter pylori (H. pylori) strains.
Tianyun Fan, Xixi Guo, Qingxuan Zeng, Wei Wei, Xuefu You, Jing Pang, Yanxiang Wang, Danqing Song   +7 more
doaj   +1 more source

The Application of Iron Nanoparticles Green‐Synthesized by Coptis chinensis Leaf Aqueous Extract in Reducing the TNF‐α and IL1‐β Inflammatory Cytokines in the Rat Periodontal Model

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Treatment of periodontitis by the iron nanoparticles. ABSTRACT The study purpose was to examine how the green‐synthesized iron nanoparticles (FeNPs) made from Coptis chinensis extract affected the TNF‐α and IL1‐β gingival levels in the rat periodontal model. The extract from C. chinensis was utilized as a green reducing agent and a great stabilizer for
Jialing Wu, Xinjie Gao, Ruiqi Li
wiley   +1 more source

Preparative separation of three isoquinoline alkaloids from Berberidis radix by pH-zone-refining countercurrent chromatography [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2018
Berberidis radix, as a traditional Chinese herbal medicine, is well known as the main source of berberine. This herbal medicine has been used for the treatment of many diseases and alkaloids including jatrorrhizine, palmatine, and berberine are major ...
Sun Changlei, Zhao Wei, Duan Wenjuan, Yang Peng, Yang Bingtian, Jiang Jiaojiao, Li Jia, Wang Xiao   +7 more
doaj   +1 more source

Indole‐3‐Acetic Acid Improves Intestinal Inflammation and Intestinal Barrier Dysfunction In Vitro via the AHR/NF‐κB Signaling Pathway

Food Frontiers, Volume 7, Issue 1, January 2026.
In this study, we found that based on the AHR/NF‐κB signaling pathway, IAA has a positive effect on the prevention and treatment of intestinal barrier function and also exhibits immunological activity. ABSTRACT Impairment of intestinal barrier function is intricately linked to intestinal inflammation.
Qiaoyu Sun, Qingqing Zhou, Sitong Ge, Danli Wu, Ping Li, Qing Gu   +5 more
wiley   +1 more source

Accelerated Wound Healing Using Biocellulose Dressings Enriched With Laportea decumana Extract in Polymicrobial Infection Wound Models

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2026, Issue 1, 2026.
Laportea decumana (Roxb.) Wedd. is known for its analgesic, antioxidant, anti‐inflammatory, and antibacterial properties. This study aimed to evaluate the wound‐healing effects of LDE incorporated into a biocellulose dressing for the treatment of polymicrobial‐infected wounds.
Yulia Yusrini Djabir, Dwi Novrianty Busaeri, Muhammad Haryandi, Nurhasni Hasan, Habibie Habibie, Djulfikri Mewar, Hien Minh Nguyen, Aryadi Arsyad, Anjali Chauhan   +8 more
wiley   +1 more source

The underlying mechanism of modified palmatine for calcified cells

四川大学学报. 自然科学版, 2018
To explore the role of palmatine in vascular calcification，we employed a calcific cell model using β-glyceophosphate to stimulate the rat aortic smooth muscle cells (RASMCs).
QIAO Jie, LI Yi, YANG Li, QI Qing-Rong, WANG Li, LIN Hong-Hui   +5 more
doaj  

The Role of Gut Microbiota in Fish Viral Infection: Mechanisms and Microbiota‐Targeted Interventions

Aquaculture Nutrition, Volume 2026, Issue 1, 2026.
Viral diseases represent one of the major threats to the global aquaculture industry. In recent years, the relationship between gut microbiota and viral infections in fish has garnered increasing attention. The gut microbiota contributes critically to fish health and is involved in antiviral defense through immune regulation, secretion of microbial ...
Qiong Zhao, Jianzhong Shao, Ye Chen, Hangjun Zhang, Lee Seong Wei   +4 more
wiley   +1 more source

Palmatine Is a Plasmid-Mediated Quinolone Resistance (PMQR) Inhibitor That Restores the Activity of Ciprofloxacin Against QnrS and AAC(6ʹ)-Ib-cr-Producing Escherichia coli

Infection and Drug Resistance, 2020
Peng Wang, 1 Longfei Hu, 1 Zhihui Hao 2 1Agricultural Bio-Pharmaceutical Laboratory, Qingdao Agricultural University, Qingdao 266109, People’s Republic of China; 2National Centre for Veterinary Drug Safety Evaluation, College of Veterinary ...
Wang P, Hu L, Hao Z
doaj  

Anti-Acetylcholinesterase Activities of Mono-Herbal Extracts and Exhibited Synergistic Effects of the Phytoconstituents: A Biochemical and Computational Study

Molecules, 2019
Alzheimer’s disease (AD), a neurodegenerative disease, is the most common form of dementia. Inhibition of acetylcholinesterase (AChE) is a common strategy for the treatment of AD. In this study, aqueous, hydro-methanolic, and methanolic extracts of
Acharya Balkrishna, Subarna Pokhrel, Meenu Tomer, Sudeep Verma, Ajay Kumar, Pradeep Nain, Abhishek Gupta, Anurag Varshney   +7 more
doaj   +1 more source

Comprehensive Experimental and Computational Characterization of a Phenylacetamide‐Based Molecule

BioMed Research International, Volume 2026, Issue 1, 2026.
The aim of this study was to synthesize Tetrahydroisoquinoline Derivative 1 (M1) and to evaluate its biological activities in the SH‐SY5Y neuroblastoma cell line. Theoretical calculations for the investigated molecule were performed using the Gaussian software package at the B3LYP, HF, and M062X levels with the 6‐31g, 6‐31++g, and 6‐31++g(d,p) basis ...
Tugba Agbektas, Farid N. Naghiyev, Burak Tüzün, Ali N. Khalilov, Ayca Tas, Cemile Zontul, Unal Ozum, Yavuz Silig, Alireza Poustforoosh, Ibrahim G. Mamedov, Poorani Gurumallesh Prabu   +10 more
wiley   +1 more source