Results 51 to 60 of about 2,409 (171)

Rhodium-Catalyzed Ortho-Vinylation of 2-Arylpyridines and Its Application in the Total Synthesis of Palmatine

Pharmaceutical Fronts, 2020
An efficient protocol by Rh-catalyzed direct C–H vinylation of 2-arylpyridines with a commercially available and air-stable potassium vinyl donor has been developed.
Shan Lv, Ruifang Nie, Lingmei Guo, Yang Zheng, Yanzhao Liu, Li Guo, Yong Wu   +6 more
doaj   +1 more source

Palmatine as an Agent Against Metabolic Syndrome and Its Related Complications: A Review

Drug Design, Development and Therapy, 2020
Sophia Ogechi Ekeuku,1 Kok-Lun Pang,1 Kok-Yong Chin1,2 1Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia; 2State Key Laboratory of Oncogenes and Related Genes, Renji-Med X Clinical Stem Cell ...
Ekeuku SO, Pang KL, Chin KY
doaj  

Indole‐3‐Acetic Acid Improves Intestinal Inflammation and Intestinal Barrier Dysfunction In Vitro via the AHR/NF‐κB Signaling Pathway

Food Frontiers, Volume 7, Issue 1, January 2026.
In this study, we found that based on the AHR/NF‐κB signaling pathway, IAA has a positive effect on the prevention and treatment of intestinal barrier function and also exhibits immunological activity. ABSTRACT Impairment of intestinal barrier function is intricately linked to intestinal inflammation.
Qiaoyu Sun, Qingqing Zhou, Sitong Ge, Danli Wu, Ping Li, Qing Gu   +5 more
wiley   +1 more source

Optimization of Deep Eutectic Solvents Extraction of Effective Components from Phellodendron chinense Schneid by Response Surface Methodology

International Journal of Chemical Engineering, 2022
Taking Phellodendron chinense Schneid (PcS) as the raw material with ultrasonic-assisted eutectic solvent, the effects of various DESs on the extractable content of palmatine and berberine in PcS were investigated. On the basis of the single-factor test,
Xianwen Yue, Yuan Cao, Yuejie Wang, Huiwei Bao, Yang Xu   +4 more
doaj   +1 more source

Discovery of palmatine derivatives as potent neuroprotective agents

Journal of Asian Natural Products Research
Alzheimer’s disease is a neurodegenerative disorder characterized by the presence of neurodegenerative lesions and cognitive impairment. In this study, a series of novel palmatine derivatives were designed and synthesized through the introduction of a heteroatom using carbodiimide-mediated condensation.
Shuo Pang, Na Chen, Zhuo Li, Zhuo-Hui Luo, Wei Dong, Shan Gao, Ning Liu, Shuo Pan, Lian-Feng Zhang, Jun Chen, Ya-Jun Yang   +10 more
openaire   +2 more sources

Synthesis and Structure–Activity Relationship of Palmatine Derivatives as a Novel Class of Antibacterial Agents against Helicobacter pylori

Molecules, 2020
Taking palmatine (PMT) as the lead, 20 new PMT derivatives were synthesized and examined for their antibacterial activities against six tested metronidazole (MTZ)-resistant Helicobacter pylori (H. pylori) strains.
Tianyun Fan, Xixi Guo, Qingxuan Zeng, Wei Wei, Xuefu You, Jing Pang, Yanxiang Wang, Danqing Song   +7 more
doaj   +1 more source

Accelerated Wound Healing Using Biocellulose Dressings Enriched With Laportea decumana Extract in Polymicrobial Infection Wound Models

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2026, Issue 1, 2026.
Laportea decumana (Roxb.) Wedd. is known for its analgesic, antioxidant, anti‐inflammatory, and antibacterial properties. This study aimed to evaluate the wound‐healing effects of LDE incorporated into a biocellulose dressing for the treatment of polymicrobial‐infected wounds.
Yulia Yusrini Djabir, Dwi Novrianty Busaeri, Muhammad Haryandi, Nurhasni Hasan, Habibie Habibie, Djulfikri Mewar, Hien Minh Nguyen, Aryadi Arsyad, Anjali Chauhan   +8 more
wiley   +1 more source

Synthesis of a water-soluble 2,2′-biphen[4]arene and its efficient complexation and sensitive fluorescence enhancement towards palmatine and berberine

Beilstein Journal of Organic Chemistry, 2018
A water-soluble 2,2′-biphen[4]arene (2,2’-CBP4) containing eight carboxylato moieties was synthesized and characterized. Its complexation behavior towards two alkaloids, palmatine (P) and berberine (B), was investigated by means of fluorescence and 1H ...
Xiayang Huang, Xinghua Zhang, Tianxin Qian, Junwei Ma, Lei Cui, Chunju Li   +5 more
doaj   +1 more source

Palmatine from Unexplored Rutidea parviflora Showed Cytotoxicity and Induction of Apoptosis in Human Ovarian Cancer Cells

Toxins, 2019
Ovarian cancer ranks amongst the deadliest cancers in the gynaecological category of cancers. This research work aims to evaluate in vitro anti-ovarian cancer activities and identify phytochemical constituents of a rarely explored plant species— ...
Okiemute Rosa Johnson-Ajinwo, Alan Richardson, Wen-Wu Li   +2 more
doaj   +1 more source

Preparative separation of three isoquinoline alkaloids from Berberidis radix by pH-zone-refining countercurrent chromatography [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2018
Berberidis radix, as a traditional Chinese herbal medicine, is well known as the main source of berberine. This herbal medicine has been used for the treatment of many diseases and alkaloids including jatrorrhizine, palmatine, and berberine are major ...
Sun Changlei, Zhao Wei, Duan Wenjuan, Yang Peng, Yang Bingtian, Jiang Jiaojiao, Li Jia, Wang Xiao   +7 more
doaj   +1 more source