Results 21 to 30 of about 7,634 (170)

Polyethylene glycolated PAMAM dendrimers-Efavirenz conjugates

International Journal of Pharmaceutical Investigation, 2014
The preparation of novel PEGylated PAMAM (poly-amidoamine) dendrimers for delivery of anti-HIV drug Efavirenz is reported.About 5.0 G PAMAM dendrimers are prepared by ethylene diamine core via Michael addition by divergent method. PEGylation is done by polyethylene glycol 600 using epichlorhydrin as linker.
Pyreddy, Suneela, Kumar, Pandurangan Dinesh, Kumar, Palanirajan Vijayaraj   +2 more
openaire   +3 more sources

The Adsorption of Heavy Metal Ions by Poly (Amidoamine) Dendrimer-Functionalized Nanomaterials: A Review

Nanomaterials, 2022
Rapid industrialization has resulted in serious heavy metal pollution. The removal of heavy metal ions from solutions is very important for environmental safety and human health.
Dandan Guo, Shaohua Huang, Yan Zhu
doaj   +1 more source

Enhancing the performance of a modified poly(ether-b-amide) blend membrane by PAMAM dendritic polymer for separation of CO2/CH4

Polymer Testing, 2023
Novel dense membranes were fabricated by blending poly(ether-b-amid), Pebax 1657, as the matrix and a poly(amidoamine) dendritic polymer (PAMAM), as the modifier, to evaluate CO2/CH4 gases separation.
Atousa Tayebi, Ali Kargari, Somaye Akbari   +2 more
doaj   +1 more source

Dendritic Poly (amidoamine) Functionalized with Magnetic Nanoparticles as Sorbent for Simultaneous Magnetic Solid-Phase Extraction of Miconazole, Clotrimazole and Tioconazole Followed by Determination via HPLC-UV [PDF]

شیمی کاربردی روز, 2023
In this study, an attempt was made to synthesize a new sorbent based on the second generation of silica coated magnetic poly(amidoamine) (Fe3O4@SiO2@PAMAM) to improve the performance of magnetic solid phase extraction (MSPE) of some antifungal drugs ...
Mohsen Shirkhodayekashani, Sayed Mehdi Ghoreishi, Milad Ghani, Behrooz Maleki   +3 more
doaj   +1 more source

PAMAM-G4 protect the N-(2-hydroxyphenyl)-2-propylpentanamide (HO-AAVPA) and maintain its antiproliferative effects on MCF-7

Scientific Reports, 2023
Our work group designed and synthesized a promissory compound N-(2-hydroxyphenyl)-2-propylpentanamide (HO-AAVPA). The HO-AAVPA is a HDAC1 inhibitor and antiproliferative in cancer cell lines.
Alma Alicia Ortiz-Morales, Juan Benjamín García-Vázquez, Manuel Jonathan Fragoso-Vázquez, Martha Cecilia Rosales-Hernández, Leticia Guadalupe Fragoso-Morales, Alan Rubén Estrada-Pérez, José Correa-Basurto   +6 more
doaj   +1 more source

Conjugation of Gentamicin to Polyamidoamine Dendrimers Improved Anti-bacterial Properties against Pseudomonas aeruginosa [PDF]

Advanced Pharmaceutical Bulletin, 2021
Purpose: This study aimed to design gentamicin-conjugated poly (amidoamine) (PAMAM) dendrimers to increase the therapeutic efficiency of gentamicin against Pseudomonas aeruginosa.
Hamed Sheykhloo, Morteza Milani, Farhood Najafi, Farhad Bani, Amir Zarebkohan   +4 more
doaj   +1 more source

Nanotoxicology of Dendrimers in the Mammalian Heart: ex vivo and in vivo Administration of G6 PAMAM Nanoparticles Impairs Recovery of Cardiac Function Following Ischemia-Reperfusion Injury

International Journal of Nanomedicine, 2020
Fawzi Babiker,1 Ibrahim F Benter,2 Saghir Akhtar3 1Department of Physiology, Faculty of Medicine, Health Science Center, Kuwait University, Kuwait City, Kuwait; 2Faculty of Medicine, Eastern Mediterranean University, Famagusta, North Cyprus, Republic of ...
Babiker F, Benter IF, Akhtar S
doaj  

Polyamidoamine Dendrimers for Enhanced Solubility of Small Molecules and Other Desirable Properties for Site Specific Delivery: Insights from Experimental and Computational Studies

Molecules, 2018
Clinical applications of many small molecules are limited due to poor solubility and lack of controlled release besides lack of other desirable properties.
Daniel M. Shadrack, Hulda S. Swai, Joan J. E. Munissi, Egid B. Mubofu, Stephen S. Nyandoro   +4 more
doaj   +1 more source

Selective Cellular Uptake and Druggability Efficacy through Functionalized Chitosan-Conjugated Polyamidoamine (PAMAM) Dendrimers

Sensors
Nanotechnology has ushered in significant advancements in drug design, revolutionizing the prevention, diagnosis, and treatment of various diseases. The strategic utilization of nanotechnology to enhance drug loading, delivery, and release has garnered ...
Ye Hu, Jian Chen, Wenyan Hu
doaj   +1 more source

Use of phosphorylated PAMAM and carboxyled PAMAM to induce dentin biomimetic remineralization and dentinal tubule occlusion

Dental Materials Journal, 2021
It is crucial to emphasize the biomineralization therapeutic method to repair etched dentin in clinic. Non-collagenous proteins (NCPs) play critical role in the biomineralization of dentine. In this paper, we synthesized the phosphate-terminated polyamidoamine dendrimer (PAMAM-PO3H2) by one-step modification successfully and examined by Fourier ...
Hejia, Qin, Jindong, Long, Jun, Zhou, Liuxian, Wu, Fangfang, Xie   +4 more
openaire   +3 more sources