Results 171 to 180 of about 36,882 (246)

Efficient Delivery of dsRNA and DNA in Cultured Silkworm Cells for Gene Function Analysis Using PAMAM Dendrimers System. [PDF]

Insects, 2019
Lu C, Li Z, Chang L, Dong Z, Guo P, Shen G, Xia Q, Zhao P.   +7 more
europepmc   +1 more source

Effect of 2nd and 3rd generation PAMAM dendrimers on proliferation, differentiation, and pro-inflammatory cytokines in human keratinocytes and fibroblasts. [PDF]

Int J Nanomedicine, 2019
Czarnomysy R, Bielawska A, Bielawski K.
europepmc   +1 more source

Comparative Evaluation of Polymeric Nanocarriers for DNA Vaccine Delivery Against <i>Avian Orthoavulavirus 1</i> in Chickens. [PDF]

Viruses
Khattab AH, Bayoumi M, Eldin ZE, Ahmed BM, Amer HM.   +4 more
europepmc   +1 more source

The antibacterial effectiveness of fourth-generation poly-amidoamine dendrimers-loaded with amoxicillin in combating methicillin-resistant Staphylococcus aureus. [PDF]

Sci Rep
Alenazi N, Alhabardi SA, Binsuwaidan R, Almutairi JA, Alsunbul M, Alanazi SS, Shakeel F.   +6 more
europepmc   +1 more source

Design and Characterization of a Bioinspired PAMAM@Poly(Caffeic Acid) Magnetite Nanocarrier for Curcumin Delivery. [PDF]

ACS Omega
Foti A, Kuznowicz M, Grześkowiak BF, Jędrzak A, Satriano C, Jesionowski T.   +5 more
europepmc   +1 more source

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The influence of surface modification on the cytotoxicity of PAMAM dendrimers

International Journal of Pharmaceutics, 2003
The influence of surface modification on the cytotoxicity of PAMAM dendrimers was examined using Caco-2 cells. Dendrimers were modified by conjugating either lauroyl chains or polyethylene glycol (PEG) 2000 onto the surface of cationic PAMAM dendrimers (G2, G3, G4).
Neil B Mckeown, Antony D'Emanuele
exaly   +4 more sources

The role of autophagy in the neurotoxicity of cationic PAMAM dendrimers

Biomaterials, 2014
Poly(amidoamine) (PAMAM) dendrimers, are among the most common classes of dendrimers that are intended for a wide range of biomedical applications and extensively investigated for brain-specific drug delivery, imaging and diagnosis. Unfortunately, neurotoxicity of PAMAM dendrimers, the underlying mechanism of which is poorly-elucidated, poses a far ...
Shaofei Wang, Yubin Li, Jiajun Fan
exaly   +3 more sources

PAMAM Dendrimers: Destined for Success or Doomed to Fail? Plain and Modified PAMAM Dendrimers in the Context of Biomedical Applications

Journal of Pharmaceutical Sciences, 2015
PAMAM (polyamidoamine) dendrimers are commonly considered promising polymers that can be successfully used in various biomedical applications. Nevertheless, direct clinical adaptations of plain unmodified PAMAM dendrimers may be limited at present, mainly because of their toxicity, unpredictable behavior in living organisms, unknown bioavailability ...
Magdalena Labieniec-Watala, Cezary Watala   +1 more
exaly   +3 more sources

PAMAM dendrimers: A multifunctional nanomaterial for ECL biosensors

Talanta, 2017
Polyamido amine (PAMAM) dendrimers have been shown to function as electrochemiluminescence (ECL) co-reactant and have the inherent capability of improving immobilization of molecules on surfaces due to their dendritic structure. Here, we investigated the combination of both of these properties as the basis for biosensor development.
Sudeshna, Chandra, Michael, Mayer, Antje J, Baeumner   +2 more
openaire   +3 more sources

Fluorescence Analysis Of PAMAM Dendrimers

, 2023
Despite their lack of conjugation, polyamidoamine (PAMAM) dendrimers are intrinsically fluorescent, and this fluorescent is somewhat manipulable through altering the dendrimer's solvent. This level of fluorescence is dependent on a number of the dendrimer's qualities: the pH of the solvent, the mass percent concentration of the dendrimer in solvent ...
Nam, Ansel
openaire   +3 more sources