Results 181 to 190 of about 36,882 (246)

Cationic PAMAM Dendrimers Disrupt Key Platelet Functions

Molecular Pharmaceutics, 2012
Poly(amidoamine) (PAMAM) dendrimers have been proposed for a variety of biomedical applications and are increasingly studied as model nanomaterials for such use.
Christopher C Gibson, Giridhar Thiagarajan, Adriana Vieira-De-Abreu   +2 more
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Fabrication of pH-sensitive superhydrophilic/underwater superoleophobic poly(vinylidene fluoride)-graft-(SiO2 nanoparticles and PAMAM dendrimers) membranes for oil-water separation.

ACS Applied Materials and Interfaces, 2020
The efficient treatment of oil-water emulsions under acidic condition remains a widespread concern. Poly(amidoamine) (PAMAM) dendrimer with hyperbranched structures and a large amount of primary and tertiary amino groups has exhibited advantages to solve
Chenjie Wei, Ligang Lin, Yiping Zhao, Xiaoye Zhang, N. Yang, Li Chen, Xiaojun Huang   +6 more
semanticscholar   +1 more source

Self-assembling of DNA and PAMAM dendrimer

2005 IEEE Engineering in Medicine and Biology 27th Annual Conference, 2005
The self-assembling of DNA and cationic polymers are of interest for their biological applications. In this paper, the interaction of DNA with PAMAM was studied by agarose gel electrophoresis, size and zeta-potential measurements and circular dichroism (CD) spectroscopy. DNA was shown to form stable complexes with PAMAM by gel electrophoresis. The mean
L Z, Zhou, X L, Yang, L, Gan, H B, Xu
openaire   +2 more sources

Incorporation of fluorescent probes into PAMAM dendrimers

Bioelectrochemistry, 2004
Interactions of two fluorescent probes 1-(trimethylammoniumphenyl)-6-phenyl-1,3,5 hexatriene p-toluenesulfonate (TMA-DPH) and 12-(9-anthroyloxy) stearic acid (12-AS) with polyamidoamine (PAMAM) dendrimers were studied. Changes in fluorescence intensity and steady-state fluorescence anisotropy of TMA-DPH and 12-AS were monitored. It was found that 12-AS
D M, Domański, B, Klajnert, M, Bryszewska   +2 more
openaire   +2 more sources

Design considerations for PAMAM dendrimer therapeutics

Bioorganic & Medicinal Chemistry Letters, 2013
We have previously shown that methotrexate (MTX) conjugated to a cancer-specific poly amido amine (PAMAM) dendrimer has a higher therapeutic index than MTX alone. Unfortunately, these therapeutics have been difficult to advance because of the complicated syntheses and an incomplete understanding of the dendrimer properties.
Sascha N, Goonewardena, Jeremy D, Kratz, Hong, Zong, Ankur M, Desai, Shengzhuang, Tang, Sarah, Emery, James R, Baker, Baohua, Huang   +7 more
openaire   +2 more sources

Application of PAMAM dendrimers in optical sensing

The Analyst, 2015
In this review, recent advances have been reported in those PAMAM dendrimer-based optical sensors that are used for the detection of pH, cations, and other analyte.
E, Soršak, J Volmajer, Valh, Š Korent, Urek, A, Lobnik   +3 more
openaire   +2 more sources

Toxicity of PAMAM dendrimers to Chlamydomonas reinhardtii

Aquatic Toxicology, 2010
In recent decades, a new class of polymeric materials, PAMAM dendrimers, has attracted marked interest owing to their unique nanoscopic architecture and their hopeful perspectives in nanomedicine and therapeutics. However, the potential release of dendrimers into the aquatic environment raises the issue about their toxicity on aquatic organisms.
Anne-Noëlle, Petit, Philippe, Eullaffroy, Timothée, Debenest, François, Gagné   +3 more
openaire   +2 more sources

Biomimetic mineralization of collagen fibrils induced by amine-terminated PAMAM dendrimers – PAMAM dendrimers for remineralization

Journal of Biomaterials Science, Polymer Edition, 2015
Achieving biomimetic mineralization of collagen fibrils by mimicking the role of non-collagenous proteins (NCPs) with biomimetic analogs is of great interest in the fields of material science and stomatology. Amine-terminated PAMAM dendrimer (PAMAM-NH2), which possesses a highly ordered architecture and many calcium coordination sites, may be a ...
Kunneng, Liang, Yuan, Gao, Jianshu, Li, Ying, Liao, Shimeng, Xiao, Xuedong, Zhou, Jiyao, Li   +6 more
openaire   +2 more sources

Glycosylated one-step PAMAM dendrimers loaded with methotrexate for target therapy in breast cancer cells MDA-MB-231

, 2020
Polyamidoamine dendrimers (PAMAM) have been extensively investigated for drug delivery in target therapy against breast cancer and other diseases, but the development of a low-cost system — especially for triple-negative breast cancer (TNBC) — remains ...
Sergio Andrés Torres-Pérez, María Del Pilar Ramos-Godínez, E. Ramón-Gallegos   +2 more
semanticscholar   +1 more source

Lactoferrin Coupled Lower Generation PAMAM Dendrimers for Brain Targeted Delivery of Memantine in Aluminum-Chloride-Induced Alzheimer's Disease in Mice.

Bioconjugate chemistry, 2019
Lower generation PAMAM dendrimers have an immense potential for drug delivery with lower toxicity, but these dendrimers yet need certain basic ameliorations.
Avinash Gothwal, H. Kumar, K. T. Nakhate, Ajazuddin, Ankumoni Dutta, Anupom Borah, U. Gupta   +6 more
semanticscholar   +1 more source