Results 41 to 50 of about 82,118 (282)

An RxLR effector from phytophthora infestans prevents re-localisation of two plant NAC transcription factors from the endoplasmic reticulum to the nucleus [PDF]

open access: yes, 2013
The plant immune system is activated following the perception of exposed, essential and invariant microbial molecules that are recognised as non-self. A major component of plant immunity is the transcriptional induction of genes involved in a wide array ...
A Block   +70 more
core   +4 more sources

The Fungal Cell Wall : Structure, Biosynthesis, and Function [PDF]

open access: yes, 2017
N.G. is funded by the Wellcome Trust via a senior investigator award and a strategic award and by the MRC Centre for Medical Mycology. C.M. acknowledges the support of the Wellcome Trust and the MRC. N.G. and C.M.
Aimanianda   +215 more
core   +1 more source

γHV68 vGAT: A Viral Pseudoenzyme Pimping for PAMPs [PDF]

open access: yesMolecular Cell, 2015
In this issue, He et al. (2015) show how herpes virus usurps a cellular metabolic enzyme to induce RIG-I deamidation and RNA-independent activation, likely to better prevent further innate immune responses.
Kolakofsky Daniel, Garcin Dominique
openaire   +4 more sources

Peptide 19-2.5 inhibits heparan sulfate-triggered inflammation in murine cardiomyocytes stimulated with human sepsis serum.

open access: yesPLoS ONE, 2015
Myocardial dysfunction in sepsis has been linked to inflammation caused by pathogen-associated molecular patterns (PAMPs) as well as by host danger-associated molecular patterns (DAMPs).
Lukas Martin   +9 more
doaj   +1 more source

Broad adsorption of sepsis-related PAMP and DAMP molecules, mycotoxins, and cytokines from whole blood using CytoSorb® sorbent porous polymer beads. [PDF]

open access: yesPLoS ONE, 2018
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. In sepsis and septic shock, pathogen-associated molecular pattern molecules (PAMPS), such as bacterial exotoxins, cause direct cellular damage ...
Maryann C Gruda   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Characteristics of innate immune physiological response induced by chitin and flg22 in pepper seedlings

open access: yesXibei zhiwu xuebao
[Objective] The study aims to examine the characteristics of innate immune physiological responses induced by chitin and flagellin-derived peptide flg22 in pepper seedlings, and to explore the relationship between innate immune physiological responses ...
GONG Xuefeng   +5 more
doaj   +1 more source

'Towards a Conceptual Framework for Innate Immunity' [PDF]

open access: yes, 2005
Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity.
Aickelin, Uwe, Twycross, Jamie
core   +3 more sources

Selective Vapor Permeation Behavior of Crosslinked PAMPS Membranes [PDF]

open access: yesPolymers, 2020
The effect of crosslinking on vapor permeation behavior of polyelectrolyte membranes was studied. Poly(2-acrylamido-2-methyl-1-propanesulfonic acid) (PAMPS) membranes were crosslinked by using crosslinkers with different lengths between the reactive ends.
Ye Ji Son   +3 more
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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