Results 91 to 100 of about 3,192,937 (245)

A bird's eye view of the potential role of NFKBIA in pan-cancer

Heliyon
In the 21st century, cancer remains a serious threat to people's health and has become a prominent public health problem. NFKBIA is involved in the pathological process of many diseases including cancer, but its specific role in pan-cancer has not yet ...
Bin Wang, Difang Sun, Haifeng Li, Jinli Chen   +3 more
doaj   +1 more source

Resource Utilization and Costs during the Initial Years of Lung Cancer Screening with Computed Tomography in Canada

, 2014
BackgroundIt is estimated that millions of North Americans would qualify for lung cancer screening and that billions of dollars of national health expenditures would be required to support population-based computed tomography lung cancer screening ...
Evans, William K., Bhatia, Rick, Soghrati, Kamyar, Johnston, Michael R., Roberts, Heidi, McWilliams, Annette, English, John C, Hwang, David M, Hwang, David M., Urbanski, Stefan, Evans, William K, Goss, Glenwood D., Tsao, Ming-Sound, Sin, Don D, Johnston, Michael R, Peacock, Stuart J., Amjadi, Kayvan, Tammemagi, Martin C., Shepherd, Frances A., Xu, Zhaolin, Nicholas, Garth, Tremblay, Alain, Regier, Dean A, Sekhon, Harmanjatinder S., Sin, Don D., Liu, Geoffrey, Peacock, Stuart J, Couture, Christian, Tan, Wan C, Finley, Richard J, Cromwell, Ian, Mayo, John R., Burrowes, Paul, English, John C., Tammemagi, Martin C, Puksa, Serge, MacEachern, Paul, Goss, Glenwood D, Cressman, Sonya, Ionescu, Diana N, Shepherd, Frances A, Lam, Stephen, Leighl, Natasha B, Bolbocean, Corneliu, Finley, Richard J., Tan, Wan C., Mayo, John R, Seely, Jean M., Martel, Simon, Leighl, Natasha B., Manos, Daria, Yee, John, Sekhon, Harmanjatinder S, Atkar-Khattra, Sukhinder, Ionescu, Diana N., Regier, Dean A., Goffin, John, Seely, Jean M, Yasufuku, Kazuhiro, Cutz, Jean-Claude   +59 more
core   +1 more source

Ultrasmall High‐Entropy Materials: Nanoscale Effects, Synthesis, and Mechanistic Insights

Advanced Functional Materials, EarlyView.
This review article focuses on sub‐10 nm high‐entropy materials that combine nanoscale design with complex compositions for next‐generation applications. ABSTRACT Ultrasmall high‐entropy nanomaterials (USHENMs, <10 nm) merge multicomponent chemistry with size‐dependent effects, forming a distinct class of materials with unprecedented properties.
Yueyue He, Wenbo Wang, Simon Schweidler, Yanjiao Ma, Ben Breitung, Torsten Brezesinski   +5 more
wiley   +1 more source

Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids

Advanced Science
Drug resistance remains a major obstacle in cancer therapy, and direct mechanical disruption of cellular structures offers a promising strategy for overcoming it, highlighting the urgent clinical need for an effective and universal pan‐cancer treatment ...
Xiaojie Yuan, Xuelin Wang, Zhongyao Chen, Shuo Wang, Weining Gao, Ziyi Chen, Runyang Li, Cheng Hao, Lei Zhang, Qiongqiong Zhang, Ke Zhang, Mei Yu, Qian Liu, Jingxuan Wang, Huiping Li, Simpkins Fiona, Jing Liu, Qiang Liu, Peng Liu, Yawei Hu   +19 more
doaj   +1 more source

Shaping Matter with Acoustic Waves: From Particles to Functional Structures

Advanced Functional Materials, EarlyView.
Acoustic‐directed assembly is reviewed as a materials‐oriented strategy for organizing particles, polymers, metals, and biological systems into functional structures. The review distinguishes reversible manipulation from permanent structure formation through medium fixation, particle fixation, and in situ material generation, highlighting routes toward
Avraham Kenigsberg, Shelly Zlotnikov, Maya Fiorentino, Yuval Elias, Ornit Nagler‐Avramovitz, Hagay Shpaisman   +5 more
wiley   +1 more source

The 5-Hydroxymethylcytosine Landscape of Prostate Cancer.

UNLABELLED: Analysis of DNA methylation is a valuable tool to understand disease progression and is increasingly being used to create diagnostic and prognostic clinical biomarkers.
Sjöström, M, Ning, Y, Witte, ON, Boutros, PC, Huang, FW, Perry, MD, Gleave, M, Zwart, W, Shrestha, R, Phillips, T, Maher, CA, He, HH, Aggarwal, R, Fraser, M, Petricca, J, Small, EJ, Quigley, DA, Bjartell, A, Ye, W, Morgans, AK, Ashworth, A, Maurice-Dror, C, Ng, SWS, Moreno-Rodriguez, T, Haffner, MC, Levy, S, Beer, TM, Gilbert, LA, Zhao, SG, Fong, L, Rettig, MB, Annala, M, Bose, R, He, C, Lloyd, P, Mahajan, NP, Cui, X-L, McCarthy, E, Chou, J, Hua, JT, Evans, CP, Feng, FY, Li, H, Chen, S, Chen, WS, Foye, A, Zoubeidi, A, Chi, KN, Lang, JM, Bergamaschi, A, Chesner, L, Tran, PT, Lundberg, A, Herberts, C, Posadas, EM, Wyatt, AW, Luo, J, Maheshwari, A, Zhang, M, Thomas, GV, Huang, J, Reiter, RE, Alumkal, JJ, Lara, PN   +63 more
core   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Cancer Research UK Cancer Awareness Measures, 2021

, 2023
copyright UK Data Service and data collection copyright owner.The Cancer Awareness Measure (CAM) was developed in 2007-8 to address the absence of a validated measure of general public awareness of cancer (Stubbings, S., Robb, K., Waller, J., Ramirez, A.,
Cancer Research UK
core  

A Versatile Microfluidic Extrusion‐Based Hydrogel Platform for Self‐Organization and Long‐Term Maintenance of Engineered 3D Lymphatic Endothelium

Advanced Healthcare Materials, EarlyView.
Microfluidic coaxial extrusion generates size‐controlled 3D lymphatic tubes from primary human dermal lymphatic endothelial cells in a defined four‐component matrix. These engineered vessels self‐organize into stable lymphatic endothelium, maintain selective macromolecular permeability for 30 days, and enable direct comparison with blood endothelial ...
Elsa Mazari‐Arrighi, Adeline Boyreau, Laura Chaillot, Wilfried Souleyreau, Laetitia Andrique, Pierre‐Olivier Guichet, Thomas Mathivet, Andreas Bikfalvi, Pierre Nassoy   +8 more
wiley   +1 more source

Targeting Bromodomain and Extra-Terminal (BET) Family Proteins in Castration-Resistant Prostate Cancer (CRPC).

, 2018
Purpose: Persistent androgen receptor (AR) signaling drives castration-resistant prostate cancer (CRPC) and confers resistance to AR-targeting therapies. Novel therapeutic strategies to overcome this are urgently required.
Crespo, M, Sharp, A, Francis, JC, Plymate, SR, Swain, A, Carreira, S, Nava Rodrigues, D, de Bono, JS, Paschalis, A, Ning, J, Sumanasuriya, S, Hughes, A, Gil, V, International SU2C/PCF Prostate Cancer Dream Team,, Seed, G, Chinnaiyan, AM, Yuan, W, Dolling, D, Neeb, A, Knight, E, Mani, RS, Raj, GV, Figueiredo, I, Welti, J, Clarke, M, Boysen, G, Halsey, WS   +26 more
core   +1 more source