Results 1 to 10 of about 1,143,151 (266)
Algorithms for Drug Sensitivity Prediction [PDF]
Algorithms, 2016 Precision medicine entails the design of therapies that are matched for each individual patient. Thus, predictive modeling of drug responses for specific patients constitutes a significant challenge for personalized therapy.
Carlos De Niz +3 more
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YRDC is a Prognostic-Related Biomarker Correlated With Immune Infiltration and Drug Sensitivity in Pan-Cancer. [PDF]
Cancer Rep (Hoboken)Background YRDC has emerged as a potential biomarker in cancer, yet its prognostic value, oncogenic mechanisms, role in immune infiltration, and anticancer drugs efficacy in pan‐cancer remained poorly understood.
Qiao L, Zhang Y, Huang P.
europepmc +2 more sources
Role of Mycobacterial Culture and Drug Sensitivity Testing Laboratory under National Tuberculosis Elimination Program for the Abolition of Tuberculosis in India by 2025 [PDF]
Journal of Clinical and Diagnostic Research, 2022 India has made a bold promise to eradicate Tuberculosis (TB) by 2025 five years ahead of the global target. Although, one-fourth of the global burden with highest new cases of TB is shown by the country.
Nandini Singh +4 more
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Bioinformatics Research on Drug Sensitivity Prediction
Frontiers in Pharmacology, 2021 Modeling-based anti-cancer drug sensitivity prediction has been extensively studied in recent years. While most drug sensitivity prediction models only use gene expression data, the remarkable impacts of gene mutation, methylation, and copy number ...
Yaojia Chen +3 more
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Clinical and Experimental Obstetrics & Gynecology, 2022 Background: Current standard chemotherapy for gynecologic malignancies consists of platinum agent and taxane though, many patients experience the relapse of disease with drug resistance making the following therapy unsuccessful.
Seiji Isonishi +3 more
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Drug sensitivity testing, a unique drug selection strategy
Advances in Biomarker Sciences and Technology, 2020 Cancer treatments become more effective now. One cause of these therapeutic promotions is based on drug selective paradigms in the clinic. A small range of drug selective paradigms (pharmacogenomics, precision-oncology, biomarkers and drug sensitivity ...
Da-Yong Lu, Ting-Ren Lu
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Identifying Drug Sensitivity Subnetworks with NETPHIX
iScience, 2020 Summary: Phenotypic heterogeneity in cancer is often caused by different patterns of genetic alterations. Understanding such phenotype-genotype relationships is fundamental for the advance of personalized medicine.
Yoo-Ah Kim +6 more
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Network-based drug sensitivity prediction
BMC Medical Genomics, 2020 Background Drug sensitivity prediction and drug responsive biomarker selection on high-throughput genomic data is a critical step in drug discovery.
Khandakar Tanvir Ahmed +5 more
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Biomedicines, 2022 [Objective] Using multi-omics research methods to explore cytolytic activity-related genes through the immunoregulatory factors HAVCR2 (TIM3) affecting the survival and prognosis of lung adenocarcinoma.
Liusheng Wu +7 more
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Эпидемиология и вакцинопрофилактика, 2023 Relevance. M. kansasii are one of the main nontuberculous bacteria pathogens causing mycobacterial infections in most European countries (including Russia).
M. V. Makarova +3 more
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