Results 21 to 30 of about 1,149,895 (267)
Frontiers in Cell and Developmental Biology, 2021 Management of laryngeal and hypopharyngeal squamous cell carcinoma (LHSCC) remains highly challenging due to highly variable therapeutic responses.
Yanbo Dong +6 more
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Drug sensitivity of Proteus species [PDF]
Journal of Clinical Pathology, 1968 The results of sensitivity test for four Proteus species were compared. P. mirabilis was, in general, more drug sensitive than the other species and P. rettgeri was the least sensitive. The conclusion was drawn that species identification of Proteus is essential in routine bacteriological diagnosis.
C T, Huang, G, Chou
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Frontiers in Immunology, 2022 Hypoxia is an important feature of the tumor microenvironment(TME) and is closely associated with cancer metastasis, immune evasion, and drug resistance.
Guangzhen Cai +10 more
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RP11-616M22.7 recapitulates imatinib resistance in gastrointestinal stromal tumor
Molecular Therapy: Nucleic Acids, 2021 Emerging evidence has shown that long non-coding RNAs (lncRNAs) play crucial roles in human cancers. However, systematic characterization of lncRNAs and their roles in gastrointestinal stromal tumor (GIST) therapy have been lacking.
Yebo Shao +9 more
doaj +1 more source
Context Sensitive Modeling of Cancer Drug Sensitivity
PLOS ONE, 2015 Recent screening of drug sensitivity in large panels of cancer cell lines provides a valuable resource towards developing algorithms that predict drug response. Since more samples provide increased statistical power, most approaches to prediction of drug sensitivity pool multiple cancer types together without distinction.
Chen, Bo-Juen +3 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier +10 more
wiley +1 more source
Frontiers in OncologyPurpose5-Fluorouracil (5-FU) resistance is considered to be a possible reason for the failure of conventional drug treatment of colorectal cancer (CRC).
Can Wang +4 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar +7 more
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Frontiers in PharmacologyObjectiveOsteosarcoma is the most common primary bone cancer with a high propensity for local invasion and metastasis. An increasing number of research studies show that telomeres play an important role in the occurrence and development of cancer.
Shihao Li, Lina Zhang, Haiyang Zhang
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei +17 more
wiley +1 more source