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Towards dense volumetric pancreas segmentation in CT using 3D fully convolutional networks [PDF]

open access: yesMedical Imaging 2018: Image Processing, 2018
Pancreas segmentation in computed tomography imaging has been historically difficult for automated methods because of the large shape and size variations between patients. In this work, we describe a custom-build 3D fully convolutional network (FCN) that
Fujiwara, Michitaka   +8 more
core   +2 more sources

Editorial Expression of Concern to: The YY1/miR-548t-5p/CXCL11 signaling axis regulates cell proliferation and metastasis in human pancreatic cancer. [PDF]

open access: yesCell Death Dis
Ge WL   +11 more
europepmc   +2 more sources

Opposite Roles of Tumor Cell Proliferation and Immune Cell Infiltration in Postoperative Liver Metastasis of PDAC

open access: yesFrontiers in Cell and Developmental Biology, 2021
BackgroundRecurrence of liver metastasis after pancreatectomy is often a predictor of poor prognosis. Comprehensive genomic analysis may contribute to a better understanding of the molecular mechanisms of postoperative liver metastasis and provide new ...
Guangfu Wang   +18 more
doaj   +1 more source

The SIX1/LDHA Axis Promotes Lactate Accumulation and Leads to NK Cell Dysfunction in Pancreatic Cancer

open access: yesJournal of Immunology Research, 2023
Background. Pancreatic cancer (PC) is a malignant cancer with poor prognosis and high mortality rate. Sine oculis homeobox homolog 1 (SIX1) participates in the development of many cancers.
Wanli Ge   +8 more
doaj   +1 more source

CA9-Related Acidic Microenvironment Mediates CD8+ T Cell Related Immunosuppression in Pancreatic Cancer

open access: yesFrontiers in Oncology, 2022
PurposeThis study aims to integrate pancreatic cancer TCGA, GEO, and single-cell RNA-sequencing (scRNA-seq) datasets, and explore the potential prognostic markers and underlying mechanisms of the immune microenvironment of pancreatic cancer through ...
Lingdi Yin   +33 more
doaj   +1 more source

Correction: A Yin-Yang 1/miR-30a regulatory circuit modulates autophagy in pancreatic cancer cells. [PDF]

open access: yesJ Transl Med
Yang C   +8 more
europepmc   +2 more sources

CircNEIL3 regulatory loop promotes pancreatic ductal adenocarcinoma progression via miRNA sponging and A-to-I RNA-editing

open access: yesMolecular Cancer, 2021
Background A growing number of studies have focused on investigating circRNAs as crucial regulators in the progression of multiple cancer types.
Peng Shen   +13 more
doaj   +1 more source

FUS-induced circRHOBTB3 facilitates cell proliferation via miR-600/NACC1 mediated autophagy response in pancreatic ductal adenocarcinoma

open access: yesJournal of Experimental & Clinical Cancer Research, 2021
Background Circular RNAs (circRNAs) are becoming a unique member of non-coding RNAs (ncRNAs) with emerging evidence of their regulatory roles in various cancers.
Taoyue Yang   +13 more
doaj   +1 more source

The Plastic Pancreas [PDF]

open access: yesDevelopmental Cell, 2013
Pancreas homeostasis is based on replication of differentiated cells in order to maintain proper organ size and function under changing physiological demand. Recent studies suggest that acinar cells, the most abundant cell type in the pancreas, are facultative progenitors capable of reverting to embryonic-like multipotent progenitor cells under injury ...
Oren Ziv, Benjamin Glaser, Yuval Dor
openaire   +3 more sources

CircSTX6 promotes pancreatic ductal adenocarcinoma progression by sponging miR-449b-5p and interacting with CUL2

open access: yesMolecular Cancer, 2022
Background circular RNAs (circRNAs) have been reported to play crucial roles in the biology of different cancers. However, little is known about the function of circSTX6 (hsa_circ_0007905) in pancreatic ductal adenocarcinoma (PDAC).
Lingdong Meng   +13 more
doaj   +1 more source

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