Results 81 to 90 of about 39,007 (262)

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Vulnerabilities of the Artificial Pancreas System and Proposed Cryptographic Solutions

open access: yes, 2020
Type I Diabetes Mellitus is the most common form of diabetes in people under the age of 30. Current treatment for Type I Diabetes Mellitus includes lifelong monitoring of blood glucose levels and administration of insulin injections, but medical advances
Mesia, Brooklyn   +11 more
core   +1 more source

Back stepping-Based-PID-Controller Designed for an Artificial Pancreas model

open access: yesAl-Khawarizmi Engineering Journal, 2011
Artificial pancreas is simulated to handle Type I diabetic patients under intensive care by automatically controlling the insulin infusion rate. A Backstepping technique is used to apply the effect of PID controller to blood glucose level since there is ...
ShaimaMahmou Mahdi   +2 more
doaj   +2 more sources

The Artificial Pancreas (semester?), IPRO 308: Developing an Artificial Pancreas IPRO 308 Final Report F06

open access: yes, 2006
The objective of this IPRO is to develop a system that will function as an artificial pancreas and will incorporate an insulin delivery system with a non invasive glucose monitor.Deliverables for IPRO 308: The Artificial Pancreas for the Fall 2006 ...
Miller, Jennifer   +10 more
core  

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

open access: yesAdvanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu   +4 more
wiley   +1 more source

The Artificial Pancreas (semester?), IPRO 308: Developing an Artificial Pancreas IPRO 308 Poster F06

open access: yes, 2006
The objective of this IPRO is to develop a system that will function as an artificial pancreas and will incorporate an insulin delivery system with a non invasive glucose monitor.Deliverables for IPRO 308: The Artificial Pancreas for the Fall 2006 ...
Miller, Jennifer   +10 more
core  

Stochastic Seasonal Models for Glucose Prediction in the Artificial Pancreas [PDF]

open access: yes, 2017
[EN] Background: Linear empirical dynamic models have been widely used for glucose prediction. The extension of the concept of seasonality, characteristic of other domains, is explored here for the improvement of prediction accuracy.
Montaser Roushdi Ali, Eslam   +5 more
core   +1 more source

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy

open access: yesAdvanced Science, EarlyView.
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang   +5 more
wiley   +1 more source

The Artificial Pancreas (semester?), IPRO 308: Developing an Artificial Pancreas IPRO 308 Abstract F06

open access: yes, 2006
The objective of this IPRO is to develop a system that will function as an artificial pancreas and will incorporate an insulin delivery system with a non invasive glucose monitor.Deliverables for IPRO 308: The Artificial Pancreas for the Fall 2006 ...
Miller, Jennifer   +10 more
core  

T‐Cell Exhaustion in the Tumor Microenvironment: Subcellular Dysfunction, Pan‐Cancer Characteristics, and Therapeutic Interventions

open access: yesAdvanced Science, EarlyView.
This study elucidates the mechanisms of subcellular multidimensional collapse in exhausted T cells. By specifically targeting the nucleus, mitochondria, and endoplasmic reticulum, strategic interventions can effectively remodel the compromised organelle network. This integrated approach drives comprehensive T cell resuscitation, ultimately establishing
Mingxing Wang   +9 more
wiley   +1 more source

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