Results 61 to 70 of about 276,664 (318)
European Journal of Medical Research, 2023 Background In recent years, conventional coagulation (CC) and thromboelastography (TEG) parameters have been reported to be closely related to the progression of pancreatic cancer (PC).
Li Jiaao +4 more
doaj +1 more source
Curriculum Knowledge Switching for Pancreas Segmentation [PDF]
ICIP 2023, 2023 Pancreas segmentation is challenging due to the small proportion and highly changeable anatomical structure. It motivates us to propose a novel segmentation framework, namely Curriculum Knowledge Switching (CKS) framework, which decomposes detecting pancreas into three phases with different difficulty extent: straightforward, difficult, and challenging.
arxiv
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
JCI Insight, 2018 BACKGROUND Neutrophils and their inflammatory mediators are key pathogenic components in multiple autoimmune diseases, while their role in human type 1 diabetes (T1D), a disease that progresses sequentially through identifiable stages prior to the ...
Federica Vecchio +22 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
BMC Gastroenterology, 2018 Background Patients with potentially resectable pancreatic ductal adenocarcinoma (PDAC) are frequently found to be unresectable on exploration due to small distant metastasis.
Xinchun Liu +7 more
doaj +1 more source
Pancreas segmentation with probabilistic map guided bi-directional recurrent UNet [PDF]
Physics in Medicine & Biology, 66(11), 115010 (2021), 2019 Pancreas segmentation in medical imaging data is of great significance for clinical pancreas diagnostics and treatment. However, the large population variations in the pancreas shape and volume cause enormous segmentation difficulties, even for state-of-the-art algorithms utilizing fully-convolutional neural networks (FCNs).
arxiv +1 more source
Single-Cell Transcriptomics of the Human Endocrine Pancreas
Diabetes, 2016 Human pancreatic islets consist of multiple endocrine cell types. To facilitate the detection of rare cellular states and uncover population heterogeneity, we performed single-cell RNA sequencing (RNA-seq) on islets from multiple deceased organ donors ...
Y. Wang +7 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Deep convolutional networks for pancreas segmentation in CT imaging [PDF]
Proc. SPIE 9413, Medical Imaging 2015: Image Processing, 94131G
(20 March 2015), 2015 Automatic organ segmentation is an important prerequisite for many computer-aided diagnosis systems. The high anatomical variability of organs in the abdomen, such as the pancreas, prevents many segmentation methods from achieving high accuracies when compared to other segmentation of organs like the liver, heart or kidneys.
arxiv +1 more source