Results 61 to 70 of about 811,378 (409)

Lymphangiogenesis and angiogenesis during human fetal pancreas development [PDF]

, 2014
Background: The complex endocrine and exocrine functionality of the human pancreas depends on an efficient fluid transport through the blood and the lymphatic vascular systems. The lymphatic vasculature has key roles in the physiology of the pancreas and
Carlotti, Françoise, Chuva de Sousa Lopes, Susana Marina, de Koning, Eelco JP, de Melo Bernardo, Ana, Mummery, Christine L, Roost, Matthias S, van Iperen, Liesbeth   +6 more
core   +1 more source

Cancer‐testis gene STK31 is regulated by methylation and promotes the development of pancreatic cancer

Cancer Medicine, 2023
Backgroud Pancreatic cancer (PC) is a highly invasive malignancy with extremely poor prognosis. STK31 has been identified as a cancer‐testis (CT) gene, but its function in PC has not been elucidated well. Methods The effect of STK31 on cell proliferation,
Hao Gao, Baobao Cai, Zipeng Lu, Guangfu Wang, Yong Gao, Yi Miao, Kuirong Jiang, Kai Zhang   +7 more
doaj   +1 more source

Multi-Contrast Computed Tomography Atlas of Healthy Pancreas [PDF]

arXiv, 2023
With the substantial diversity in population demographics, such as differences in age and body composition, the volumetric morphology of pancreas varies greatly, resulting in distinctive variations in shape and appearance. Such variations increase the difficulty at generalizing population-wide pancreas features. A volumetric spatial reference is needed
arxiv  

Extracellular matrix scaffold and hydrogel derived from decellularized and delipidized human pancreas

Scientific Reports, 2018
Extracellular matrix (ECM) plays an important developmental role by regulating cell behaviour through structural and biochemical stimulation. Tissue-specific ECM, attained through decellularization, has been proposed in several strategies for tissue and ...
S. Sackett, Daniel M. Tremmel, Fengfei Ma, Austin K. Feeney, Rachel M. Maguire, Matthew E Brown, Ying Zhou, Xia Li, Cori O’Brien, Lingjun Li, W. Burlingham, J. Odorico   +11 more
semanticscholar   +1 more source

A meta-analysis of Prognostic factor of Pancreatic neuroendocrine neoplasms

Scientific Reports, 2018
Pancreatic neuroendocrine neoplasms (pNENs) are a group of clinically rare and heterogeneous diseases of the pancreas. However, the prognostic factors for this disease in patients still remain controversial.
Yong Gao, Hao Gao, Guangfu Wang, Lingdi Yin, Wenbin Xu, Yunpeng Peng, Junli Wu, Kuirong Jiang, Yi Miao   +8 more
doaj   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

NIH Initiative to Improve Understanding of the Pancreas, Islet, and Autoimmunity in Type 1 Diabetes: The Human Pancreas Analysis Program (HPAP)

Diabetes, 2019
Type 1 diabetes risk can reliably be predicted by markers of autoimmunity, but approaches to prevent or modify the underlying disease process are needed.
K. Kaestner, A. Powers, A. Naji, M. Atkinson   +3 more
semanticscholar   +1 more source

Deciphering the molecular mechanism of tetrandrine in inhibiting hepatocellular carcinoma and increasing sorafenib sensitivity by combining network pharmacology and experimental evaluation

Pharmaceutical Biology, 2022
Context The mechanism of tetrandrine (TET) in hepatocellular carcinoma (HCC) progression and sorafenib (Sora) chemosensitivity deserves investigation. Objective Using network pharmacology approaches to elucidate the mechanisms of TET in HCC.
Biao Niu, Sidong Wei, Jianjun Sun, Huibo Zhao, Bing Wang, Guoyong Chen   +5 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Diagnosis of pancreatic disease in feline platynosomosis [PDF]

, 2017
Objectives: Platynosomum species are cat-specific parasitic trematodes that parasitize the biliary ducts and gall bladder. Due to the common connection to the major duodenal papilla of the pancreas and common bile ducts in addition to the periductal ...
Illanes, Oscar, Ketzis, Jennifer, Köster, Liza, Rajeev, Sreekumari, Shell, Linda   +4 more
core   +1 more source