Results 21 to 30 of about 65,267 (260)

An indolent pancreatic ductal adenocarcinoma with psammoma bodies and a coincidental neuroendocrine tumor

Human Pathology: Case Reports, 2019
Pancreatic ductal adenocarcinoma is a very aggressive neoplasm with a low survival rate, comprising the majority of pancreatic malignancies. Psammoma bodies have rarely been reported in pancreatic ductal adenocarcinoma, and their clinicopathologic ...
Hongxing Gui, Christopher P. Julien, Suehyb G. Alkhatib, Michael A. Husson   +3 more
doaj   +1 more source

Immune response and drug therapy based on ac4C-modified gene in pancreatic cancer typing

Frontiers in Immunology, 2023
N-4 cytidine acetylation (ac4C) is an epitranscriptome modification catalyzed by N-acetyltransferase 10 (NAT10) and is essential for cellular mRNA stability, rRNA biosynthesis, cell proliferation, and epithelial-mesenchymal transition (EMT).
Dong Xu, Kaige Huang, Yang Chen, Fei Yang, Cunbing Xia, Hongbao Yang   +5 more
doaj   +1 more source

How fibrosis influences imaging and surgical decisions in pancreatic cancer

Frontiers in Physiology, 2012
Our understanding of pancreatic ductal adenocarcinoma is shifting away from a disease of malignant ductal cells-only, towards a complex system where tumor evolution is a result of interaction of cancer cells with their microenvironment.
Mert eErkan, Simone eHausmann, Christoph W Michalski, Melissa eSchlitter, Alexander A Fingerle, Martin eDobritz, Helmut eFriess, Jörg eKleeff   +7 more
doaj   +1 more source

Label-free proteomics reveals serum proteins whose levels differ between pancreatic ductal adenocarcinoma patients with short or long survival

Tumor Biology, 2020
Pancreatic ductal adenocarcinoma is the most common and aggressive type of pancreatic cancer, with a 5-year survival rate that is less than 10%. New biomarkers to aid in predicting the prognosis of pancreatic ductal adenocarcinoma patients are needed ...
Matilda Holm, Mayank Saraswat, Sakari Joenväärä, Hanna Seppänen, Risto Renkonen, Caj Haglund   +5 more
doaj   +1 more source

A case report of a collision tumor composed of pancreatic ductal adenocarcinoma and peri-pancreatic mucosa-associated lymphoid tissue lymphoma

World Journal of Surgical Oncology, 2023
Background Collision tumors are composed of two distinct tumor components. Collision tumors composed of pancreatic ductal adenocarcinoma and malignant lymphoma occurring in the pancreas have not been previously described in the scientific literature.
Ryuji Hirai, Ken-ichi Omae, Mitsuko Yodoya, Syunji Fujie, Masayoshi Fujii, Kazuma Iwata, Kentaro Imanishi, Eisuke Kurihara, Kazuhiro Yoshida, Masaru Jida, Kazuyasu Kobayashi, Yoshiaki Kanaya, Syuichiro Maruyama   +12 more
doaj   +1 more source

Effect of miR-184 on Proliferation and Apoptosis of Pancreatic Ductal Adenocarcinoma and Its Mechanism

Technology in Cancer Research & Treatment, 2020
Objective: Previous studies have shown that abnormal expression of microRNA-184 leads to a variety of cancers, including pancreatic ductal adenocarcinoma, suggesting microRNA-184 as a new treatment target for pancreatic ductal adenocarcinoma.
Shentao Li MBBS, He Li MD, PhD, Weiwei Ge PhD, Kai Song MM, Chunyu Yuan MM, Ran Yin MBBS   +5 more
doaj   +1 more source

Loss of BAP1 Expression Is Very Rare in Pancreatic Ductal Adenocarcinoma. [PDF]

PLoS ONE, 2016
BACKGROUND:Pancreatic cancer is both common and highly lethal and therefore new biomarkers or potential targets for treatment are needed. Loss of BRCA associated protein-1 (BAP1) expression has been found in up to a quarter of intrahepatic ...
Michael Tayao, Juliana Andrici, Mahtab Farzin, Adele Clarkson, Loretta Sioson, Nicole Watson, Terence C Chua, Tamara Sztynda, Jaswinder S Samra, Anthony J Gill   +9 more
doaj   +1 more source

Hypoxia induces oncogene yes-associated protein 1 nuclear translocation to promote pancreatic ductal adenocarcinoma invasion via epithelial–mesenchymal transition

Tumor Biology, 2017
Pancreatic ductal adenocarcinoma is one of the most lethal cancers. The Hippo pathway is involved in tumorigenesis and remodeling of tumor microenvironments.
Honglong Wei, Zongzhen Xu, Feng Liu, Fuhai Wang, Xin Wang, Xueying Sun, Jie Li   +6 more
doaj   +1 more source

MiR-590 Suppresses Proliferation and Induces Apoptosis in Pancreatic Cancer by Targeting High Mobility Group A2

Technology in Cancer Research & Treatment, 2020
Background: Pancreatic ductal adenocarcinoma is a common malignancy with high morbidity. MicroRNAs have been demonstrated to be critical posttranscriptional regulators in tumorigenesis.
Ya-Dong Wang MD, Jia-Ding Mao PhD, Jun-Feng Wang MD, Mao-Qi Xu MD   +3 more
doaj   +1 more source

Expression and clinical significance of placenta-specific 1 in pancreatic ductal adenocarcinoma

Tumor Biology, 2017
The limited efficacy of conventional therapies for pancreatic ductal adenocarcinoma has led to the growing interest for identifying potential antigenic targets for immunotherapy.
Yin Yin, Xu Zhu, Shanshan Huang, Jiawei Zheng, Mengyun Zhang, Wencui Kong, Qun Chen, Yan Zhang, Xiong Chen, Kerong Lin, Xuenong Ouyang   +10 more
doaj   +1 more source