Results 21 to 30 of about 129,296 (209)

Collision of ductal adenocarcinoma and neuroendocrine tumor of the pancreas: a case report and review of the literature [PDF]

, 2017
Background: Simultaneous occurrence of exocrine and neuroendocrine tumors of the pancreas is very infrequent. We report a patient with an endocrine tumor in the pancreatic-duodenal area and extensive exocrine carcinoma involving the whole pancreas.
Blandamura, Stella, Da Dalt, Gianfranco, Merigliano, Stefano, Pozza, Gioia, Serafini, Simone, Sperti, Cosimo, Valmasoni, Michele   +6 more
core   +2 more sources

Label-free proteomics reveals serum proteins whose levels differ between pancreatic ductal adenocarcinoma patients with short or long survival

Tumor Biology, 2020
Pancreatic ductal adenocarcinoma is the most common and aggressive type of pancreatic cancer, with a 5-year survival rate that is less than 10%. New biomarkers to aid in predicting the prognosis of pancreatic ductal adenocarcinoma patients are needed ...
Matilda Holm, Mayank Saraswat, Sakari Joenväärä, Hanna Seppänen, Risto Renkonen, Caj Haglund   +5 more
doaj   +1 more source

A case report of a collision tumor composed of pancreatic ductal adenocarcinoma and peri-pancreatic mucosa-associated lymphoid tissue lymphoma

World Journal of Surgical Oncology, 2023
Background Collision tumors are composed of two distinct tumor components. Collision tumors composed of pancreatic ductal adenocarcinoma and malignant lymphoma occurring in the pancreas have not been previously described in the scientific literature.
Ryuji Hirai, Ken-ichi Omae, Mitsuko Yodoya, Syunji Fujie, Masayoshi Fujii, Kazuma Iwata, Kentaro Imanishi, Eisuke Kurihara, Kazuhiro Yoshida, Masaru Jida, Kazuyasu Kobayashi, Yoshiaki Kanaya, Syuichiro Maruyama   +12 more
doaj   +1 more source

Contribution of galectin-1, a glycan-binding protein, to gastrointestinal tumor progression [PDF]

, 2017
Gastrointestinal cancer is a group of tumors that affect multiple sites of the digestive system, including the stomach, liver, colon and pancreas. These cancers are very aggressive and rapidly metastasize, thus identifying effective targets is crucial ...
Bacigalupo, Maria Lorena, Carabias, Pablo, Troncoso, María Fernanda   +2 more
core   +1 more source

Effect of miR-184 on Proliferation and Apoptosis of Pancreatic Ductal Adenocarcinoma and Its Mechanism

Technology in Cancer Research & Treatment, 2020
Objective: Previous studies have shown that abnormal expression of microRNA-184 leads to a variety of cancers, including pancreatic ductal adenocarcinoma, suggesting microRNA-184 as a new treatment target for pancreatic ductal adenocarcinoma.
Shentao Li MBBS, He Li MD, PhD, Weiwei Ge PhD, Kai Song MM, Chunyu Yuan MM, Ran Yin MBBS   +5 more
doaj   +1 more source

Metformin as an Adjunctive Therapy for Pancreatic Cancer: A Review of the Literature on Its Potential Therapeutic Use [PDF]

, 2018
Pancreatic ductal adenocarcinoma has the worst prognosis of any cancer. New adjuvant chemotherapies are urgently required, which are well tolerated by patients with unresectable cancers.
A Hwang, A Isakovic, A Jo, A Kim, A Somogyi, A Tomimoto, A Vazquez-Martin, A Woods, AD Morris, Andrew R. Hart, AT Nies, B Liu, CJ Bailey, CJ Bailey, CJ Currie, CM Ambe, D Iliopoulos, D Ish-Shalom, DG Hardie, DG Hardie, DG Hardie, EJ Brown, G Zhou, GG Graham, H Takane, HA Hirsch, I Tkac, IB Sahra, IN Alimova, J Muller, JPT Higgins, K Cusi, K Inoki, K Polyak, K Zhou, K Zhou, L-W Wang, LA Cantrell, LL Campbell, M Bodmer, M Cerullo, M Pollak, M Reni, M Zhou, MA Frouws, MA Tempero, ML Goalstone, MM Kozak, MN Cook, MR Owen, N Leeuwen van, N Sadeghi, Philip J. Broadhurst, R Chaiteerakij, RC Turner, RM Memmott, S Amin, S Kordes, S Singh, S Wullschleger, SA Hawley, SE Kahn, SH Lee, SW Yee, T Conroy, T Conroy, T Higurashi, VN Anisimov, X Huang, X-S Deng, Y Choi, Y Shi, Y Zhao, Y Zhuang   +73 more
core   +1 more source

Loss of BAP1 Expression Is Very Rare in Pancreatic Ductal Adenocarcinoma. [PDF]

PLoS ONE, 2016
BACKGROUND:Pancreatic cancer is both common and highly lethal and therefore new biomarkers or potential targets for treatment are needed. Loss of BRCA associated protein-1 (BAP1) expression has been found in up to a quarter of intrahepatic ...
Michael Tayao, Juliana Andrici, Mahtab Farzin, Adele Clarkson, Loretta Sioson, Nicole Watson, Terence C Chua, Tamara Sztynda, Jaswinder S Samra, Anthony J Gill   +9 more
doaj   +1 more source

Hypoxia induces oncogene yes-associated protein 1 nuclear translocation to promote pancreatic ductal adenocarcinoma invasion via epithelial–mesenchymal transition

Tumor Biology, 2017
Pancreatic ductal adenocarcinoma is one of the most lethal cancers. The Hippo pathway is involved in tumorigenesis and remodeling of tumor microenvironments.
Honglong Wei, Zongzhen Xu, Feng Liu, Fuhai Wang, Xin Wang, Xueying Sun, Jie Li   +6 more
doaj   +1 more source

ROCK signalling induced gene expression changes in mouse pancreatic ductal adenocarcinoma cells [PDF]

, 2016
The RhoA and RhoC GTPases act via the ROCK1 and ROCK2 kinases to promote actomyosin contraction, resulting in directly induced changes in cytoskeleton structures and altered gene transcription via several possible indirect routes.
Clark, William, Kalna, Gabriela, Olson, Michael F., Rath, Nicola   +3 more
core   +1 more source

Inhibition of HIF-1 alpha by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma [PDF]

, 2015
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Acland, Assenat, Bazhin, Carbone, Chaput, Chen, Chouaib, Danenberg, David, Dyson, El-Deiry, Gallick, Gelovani, Ghansah, Giese, Gil, Gress, Gribben, Hao, Hao, Hao, Henson, Jemal, Kiessling, Kroemer, Kroemer, Kroemer, Levi, Luo, Mi, Moses, Plate, Powis, Powis, Powis, Ravichandran, Ricci, Rodeck, Sarker, Schuler, Semenza, Singh, Spisek, Tani, Vandenabeele, Wang, Wang, Zitvogel, Zitvogel, Zitvogel   +49 more
core   +1 more source