Results 41 to 50 of about 14,407 (231)

Assessment of Exocrine Pancreatic Insufficiency in Type 2 Diabetic Mellitus Patients Presenting with Dyspepsia: A Cross-sectional Observational Study [PDF]

Avicenna Journal of Medical Biochemistry
Background: Diabetes mellitus (DM) virtually affects the gastrointestinal (GI) tract in protean ways, including but not limited to small intestinal bacterial overgrowth, GI reflux disease, gastroparesis, neuropathy, pancreatopathy, and non-alcoholic ...
Nidhi Bhutra, Ravi Kant
doaj   +1 more source

IL‐4/STAT6‐signaling Influences Local Inflammation and Regeneration Processes During Acute Pancreatitis and Promotes Fibrosis by a Direct Activation of Pancreatic Fibroblasts During Chronic Pancreatitis

Advanced Science, EarlyView.
IL‐4/IL‐13/STAT6 signaling plays a crucial for the suppression of pro‐inflammation during acute pancreatitis and supports acinar cell regeneration but has only minor impact on fibrogenesis during chronic form of the disease. IL‐4/IL‐13 induce the expression of certain collagens directly in pancreatic fibroblasts via STAT6 activation, whereas ...
ElSheikh H, Salvers A, Piesker J, Buchholz S, Lange R, Ameling S, Steil L, Hammer E, Homuth G, Völker U, Bröker BM, Weiss FU, Sendler M, Glaubitz J   +13 more
wiley   +1 more source

Polydatin Protects Against the Formation of PPE-Induced Abdominal Aortic Aneurysms in Mice by Activating Nuclear Factor Erythroid 2-Related Factor 2. [PDF]

Drug Dev Res
ABSTRACT Sudden death resulting from abdominal aortic aneurysm (AAA) rupture is a highly fatal cardiovascular condition. There remains an urgent need to identify innovative therapeutic strategies capable of decelerating AAA progression and rupture. Although polydatin (PLD) has been consistently shown to exert potent anti‐inflammatory effects in diverse
Liu Z, Zhu J, Zhou Q, Qian H, Cui F.
europepmc   +2 more sources

Exploring the Vasculitis‐Tumors Link: Epidemiological Patterns, Mechanistic Insights, and Clinical Implications

Advanced Science, EarlyView.
This review outlines association between vasculitis and malignancies and provides practical value for clinicians in distinguishing primary vasculitis from malignancy‐associated forms and optimizing patient surveillance, improving recognition of tumor‐associated vasculitis to reduce the risk of misdiagnosis, supporting more accurate clinical decision ...
Xiaofei Shi, Zhijiao Li, Xin Ma, Bei Zhang, Xinfeng Wu, Hua Fan, Rongzeng Liu, Hongwei Jiang, Cong‐Qiu Chu   +8 more
wiley   +1 more source

The specificity of purified porcine pancreatic elastase [PDF]

Biochemical Journal, 1969
An electrophoretically homogeneous elastase preparation free from tryptic and chymotryptic activities was obtained by chromatography on DEAE-Sephadex and CM-cellulose. This preparation exhibits a narrower specificity towards peptide bonds than that observed by Naughton & Sanger (1961).
A S, Narayanan, R A, Anwar
openaire   +2 more sources

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Pancreatic function in children with non-alcoholic fatty pancreas disease

Zaporožskij Medicinskij Žurnal, 2019
Objective. To study the features of pancreatic function in children with pancreatic steatosis. Materials and methods. We examined 77 children; the average age of patients was (11.59 ± 2.82) years.
Yu. M. Stepanov, O. Yu. Lukianenko, N. Yu. Zavhorodnia, O. M. Tatarchuk, N. H. Hravirovska, I. A. Klenina   +5 more
doaj   +1 more source

Evaluation of malnutrition with blood ghrelin and fecal elastase levels in acute decompensated heart failure patients

Türk Kardiyoloji Derneği Arşivi, 2015
Objectives: Exocrine pancreatic dysfunction may contribute to malnutrition and lack of appetite in the advanced stages of heart failure. Nutritional assessment was carried out on patients diagnosed with mild or moderate/severe heart failure.
Mustafa Özcan, Güzin Zeren Öztürk, Murat Köse, Samim Emet, Şengül Aydın, Kadem Arslan, Yücel Arman, Vakur Akkaya, Tufan Tükek   +8 more
doaj   +1 more source

Features of Pancreatic Pathology in Children

Gastroenterologìa, 2016
Background. The prevalence of pancreatitis in children with digestive disorders is 5–25 %. Aim of research: to determine the prevalence of pancreatic pathology in children. Material and methods.
T.V. Sorokman, O.-M.V. Popelyuk
doaj   +1 more source

An aqueous pomegranate peel extract (Punica granatum) protect against Elastase-induced pulmonary emphysema in Sprague Dawley rats model

Brazilian Journal of Pharmaceutical Sciences, 2021
We investigated the effect of Punica granatum peel aqueous extract (PGE), on pulmonary inflammation and alveolar degradation induced by intratracheal administration of Elastase in Sprague Dawley rats.
Zioud Fatma, Martín-Barrasa Jose Luis, Espinosa De Los Monteros Y Zaya Antonio, Santana Reyes Laura, Herráez Thomas Pherraez, González Martín Jesús María, Ramos-Nuez Ángela, Bachoual Rafik   +7 more
doaj   +1 more source