Results 41 to 50 of about 25,336 (285)

Accuracy of simultaneous measurement of serum biomarkers: Carbohydrate antigen 19-9, pancreatic elastase-1, amylase, and lipase for diagnosing pancreatic ductal adenocarcinoma

Journal of the Formosan Medical Association, 2022
Background: Pancreatic cancer is difficult to diagnose early since tumor markers have low sensitivity and specificity. We simultaneously measured serum carbohydrate antigen (CA) 19-9, pancreatic elastase-1, lipase, and amylase, and evaluated the accuracy
Chi-Ying Yang, Ro-Ting Lin, Chi-Yi Chen, Chun-Chieh Yeh, Chao-Ming Tseng, Wen-Hsin Huang, Teng-Yu Lee, Chia-Shen Chu, Jaw-Town Lin   +8 more
doaj  

The effects of a plant proteinase inhibitor from Enterolobium contortisiliquum on human tumor cell lines [PDF]

, 2011
Supplementary to the efficient inhibition of trypsin, chymotrypsin, plasma kallikrein, and plasmin already described by the EcTI inhibitor from Enterolobium contortisiliquum, it also blocks human neutrophil elastase (K(iapp)=4.3 nM) and prevents phorbol ...
Bhoola K.D., Bjorklund M., Chao J.C., Dani R., Foekens J.A., Fritz H., Germanov E., Hildenbrand R., Kallakury B.V., Macedo M.L., Miyasaka M., Moll U.M., Ohkoshi M., Oliva M.L., Skrzydlewska E., Stanton H., Stearns M.   +16 more
core   +1 more source

Prevalence of end-organ damage, beta cell reserve, and exocrine pancreas defect in fibrocalculous pancreatic diabetes: An Eastern India perspective

Indian Journal of Endocrinology and Metabolism, 2019
Background: Data on prevalence and burden of end-organ damage in fibrocalculous pancreatic diabetes (FCPD) from eastern India is scant. This study investigated the burden of end-organ damage and exocrine pancreatic defect in FCPD patients in Eastern ...
Beatrice Anne, Sujoy Ghosh, Ipsita Ghosh, Sayantan Ray, Subhankar Chowdhury, Deep Dutta   +5 more
doaj   +1 more source

Evaluation of Ionic Liquids and Ionic Liquids Active Pharmaceutical Ingredients Inhibition in Elastase Enzyme Activity

Molecules, 2021
Human neutrophil elastase (HNE) is used as diagnostic biomarker for inflammation/infection. In this work, 10 ionic liquids (ILs) and 11 ionic liquids active pharmaceutical ingredients (ILs-APIs) were tested to evaluate the inhibition effect on the ...
Fátima A. R. Mota, Sarah A. P. Pereira, André R. T. S. Araujo, M. Lúcia M. F. S. Saraiva   +3 more
doaj   +1 more source

The kunitz domain protein BLI-5 plays a functionally conserved role in cuticle formation in a diverse range of nematodes [PDF]

, 2010
The cuticle of parasitic nematodes performs many critical functions and is essential for proper development and for protection from the host immune response.
Antony P. Page, Bernard, Blaxter, Chu, Cook, Fessler, Ford, Frand, Ghedin, Gillian McCormack, Gillian Stepek, Hawdon, Johnstone, Johnstone, Kingston, Kingston, Kramerova, Kramerova, Kress, Mieszczanek, Milstone, Nagano, Novelli, Novelli, Paesen, Page, Page, Poole, Priess, Redmond, Rhoads, Sasaki, Scott, Shamansky, Skuce, Stanssens, Studier, Thacker, Thacker, Thacker, Thacker, Thein, Wells, Winter   +43 more
core   +1 more source

Early Detection and Localization of Pancreatic Cancer by Label-Free Tumor Synthesis [PDF]

arXiv, 2023
Early detection and localization of pancreatic cancer can increase the 5-year survival rate for patients from 8.5% to 20%. Artificial intelligence (AI) can potentially assist radiologists in detecting pancreatic tumors at an early stage. Training AI models require a vast number of annotated examples, but the availability of CT scans obtaining early ...
arxiv  

Production of Secretory Leucocyte Protease Inhibitor (SLPI) in Human Pancreatic β-Cells

Mediators of Inflammation, 1999
Secretory leucocyte protease inhibitor (SLPI) is a potent inhibitor of granulocyte elastase and cathepsin G, and also an inhibitor of pancreatic enzymes like trypsin, chymotrypsin and pancreatic elastase.
Max Nyström, Magnus Bergenfeldt, Irena Ljungcrantz, Èsa Lindeheim, Kjell Ohlsson   +4 more
doaj   +1 more source

Improved Pancreatic Tumor Detection by Utilizing Clinically-Relevant Secondary Features [PDF]

arXiv, 2022
Pancreatic cancer is one of the global leading causes of cancer-related deaths. Despite the success of Deep Learning in computer-aided diagnosis and detection (CAD) methods, little attention has been paid to the detection of Pancreatic Cancer. We propose a method for detecting pancreatic tumor that utilizes clinically-relevant features in the ...
arxiv  

Measurement of the Proteinase Inhibitors of the Bovine Pancreas by Radioimmunoassay [PDF]

, 1976
Bovine pancreas contains two polypeptide trypsin inhibitors that are not homologous and differ in their inhibitory activity towards chymotrypsin, kallikrein, elastase, and other serine proteinases. The Kunitz inhibitor and the Kazal inhibitor are present
Fink, Edwin, Greene, Lewis J., Peeters, H.   +2 more
core   +1 more source

Functional Features of the Pancreas during Chronic Pancreatitis

Gastroenterologìa, 2016
Aim of study: to identify functional status of pancreas in patients with chronic pancreatitis depending on the stage of fibrotic transformation and activity of parenchymal inflammation. Materials and methods.
B.F. Shevchenko, A.M. Babiy, O.М. Tatarchuk, V.A. Makarchuk, V.E. Kudryavtseva   +4 more
doaj   +1 more source