Results 111 to 120 of about 116,954 (354)

Long Term Metabolic Outcomes Following Pancreatectomy and Autologous Islet Transplantation: Systematic Review and Meta‐Analysis

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT This systematic review and meta‐analysis assessed long‐term outcomes following total pancreatectomy with islet autotransplantation (TPIAT). Seventeen studies including 1332 patients were analyzed. The pooled insulin independence rate was 34%, with higher rates for non‐chronic pancreatitis indications (68%) versus chronic pancreatitis (33 ...
Daniel L. Hughes   +8 more
wiley   +1 more source

Challenges and Opportunities in State‐of‐the‐Art Proteomics Analysis for Biomarker Development From Plasma Extracellular Vesicles

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound particles secreted by cells, playing crucial roles in intercellular communication. The composition of EVs can undergo changes in response to stress and disease conditions, making them excellent biomarker candidates.
Panshak P. Dakup   +11 more
wiley   +1 more source

A novel therapeutic strategy for pancreatic neoplasia using a novel RNAi platform targeting PDX-1 [PDF]

open access: yes, 2011
Bi-functional shRNA (bi-shRNA), a novel RNA interference (RNAi) effector platform targeting PDX-1 utilizing a systemic DOTAP-Cholesterol delivery vehicle, was studied in three mouse models of progressive pancreatic neoplasia.
Charles Brunicardi   +13 more
core   +1 more source

Baicalin Restores the Hypoglycemic Effect of Metformin by Regulating the Microbial Imidazole Propionate and Short‐Chain Fatty Acids

open access: yesPhytotherapy Research, EarlyView.
Baicalin restores the hypoglycemic effect of metformin by decreasing the serum imidazole propionate. ABSTRACT Gut microbiota dysbiosis is implicated in metformin non‐response. This study aimed to investigate whether baicalin, a microbiota‐modulating flavonoid derived from Radix Scutellariae, could restore metformin sensitivity and explored the ...
Aiting Wang   +5 more
wiley   +1 more source

The features of beta-cells organization in the pancreas of spontaneously hypertensive rat (SHR)

open access: yesPatologìâ, 2016
The control of b-cells pool in patients with hypertension is an actual problem, as it is possible that the hereditary genetic defects of arterial hypertension formation may affect the mechanisms of endocrine cell mass maintenance in pancreas and cause ...
T. V. Abramova, Yu. M. Kolesnyk
doaj   +1 more source

Elevated beta‐hydroxybutyrate within a pediatric population and its associated pathology: A retrospective case series

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Elevated beta‐hydroxybutyrate (BHB) is a marker for ketoacidosis. Post‐mortem values for the diagnosis of fatal ketoacidosis and the associated clinical and histologic findings are limited in the pediatric population. A retrospective case series of pediatric autopsy records and histology slides was conducted.
Nasim Haghandish   +3 more
wiley   +1 more source

Altered microvasculature in pancreatic islets from subjects with type 1 diabetes

open access: yesPLoS ONE, 2022
Aims The transcriptome of different dissociated pancreatic islet cells has been described in enzymatically isolated islets in both health and disease. However, the isolation, culturing, and dissociation procedures likely affect the transcriptome profiles,
Louise Granlund   +4 more
doaj  

Preservation of Beta cell function in adult human pancreatic islets for several months in vitro [PDF]

open access: bronze, 1979
Jens Høiriis Nielsen   +3 more
openalex   +1 more source

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