Results 141 to 150 of about 116,954 (354)

Unraveling A‐β+ ketosis‐prone diabetes: An evolving diagnosis with an elusive pathogenesis

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Since the discovery of insulin over a century ago, how we conceptualize, describe and treat diabetes has evolved, paving the way for the identification of distinct diabetes subgroups and individualized treatment options. Historically, the term ketosis‐prone diabetes (KPD) has comprised a group of diabetes syndromes characterized by severe ...
Nina Suda, Gabrielle Page‐Wilson, Jacqueline Lonier, Utpal B. Pajvani   +3 more
wiley   +1 more source

A 1 week IGF-1 infusion decreases arterial insulin concentrations but increases pancreatic insulin content and islet vascularity in fetal sheep [PDF]

, 2018
Alicia White, Samantha Louey, Eileen I. Chang, Brit H Boehmer, David A. Goldstrohm, Sonnet S. Jonker, Paul J. Rozance   +6 more
openalex   +1 more source

Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides. [PDF]

, 2018
Tissue-specific autoimmunity occurs when selected antigens presented by susceptible alleles of the major histocompatibility complex are recognized by T cells.
Anderson, Mark S, Lichti, Cheryl F, Santambrogio, Laura, Taniguchi, Ruth, Unanue, Emil R, Vomund, Anthony N, Wan, Xiaoxiao, Zakharov, Pavel N, Zinselmeyer, Bernd H   +8 more
core  

Characteristics of type 1 diabetes in Northwest China: A multicenter hospital‐based study

Journal of Diabetes Investigation, EarlyView.
This study provided an overview of the characteristics of type 1 diabetes patients in Northwest China, a region with low incidence and limited healthcare resources, highlighting the necessity of enhancing public awareness and long‐term disease education and management. ABSTRACT Objective To comprehensively analyze the characteristics of type 1 diabetes
Yue Zhang, Xiaoning Liu, Xueni Yang, Yujie Zhang, Mengmeng Shang, Limin Tian   +5 more
wiley   +1 more source

HISTOMORPHOLOGICAL PECULIARITIES OF THE PANCREATIC PARENCHYMA IN RATS WITH ALLOXAN-INDUCED DIABETES OF DIFFERENT DURATION

Неонатологія, хірургія та перинатальна медицина
The study of pathohistological and morphofunctional changes in the endocrine pancreas is an integral part of experimental diabetology, which allows obtaining a signifi cant amount of information on various aspects of the etiology and pathogenesis of ...
О. Оленович, Т. Бойчук, І. Давиденко, О. Давиденко   +3 more
doaj   +1 more source

Pancreatic Islets Accumulate Cadmium in a Rodent Model of Cadmium-Induced Hyperglycemia [PDF]

, 2020
Ryan T. Fitzgerald, Andrew Olsen, Jessica Nguyen, Winifred P.S. Wong, Malek El Muayed, Joshua Edwards   +5 more
openalex   +1 more source

The Diabetic Dog as a Translational Model for Human Islet Transplantation. [PDF]

, 2017
The dog model has served as the primary method for early development of many diabetes therapies, including pancreatic islet transplantation techniques and immunosuppressive protocols.
Adin, Christopher A, Gilor, Chen
core  

CD36 and Its Role in Obesity

Obesity Reviews, EarlyView.
ABSTRACT Obesity is understood as a condition driven by interactions between genetics and environmental factors. The role of CD36 in the regulation of lipid metabolism and ectopic fat accumulation emerges as a key area of interest. This review presents CD36 not only as a crucial facilitator of fatty acid uptake but also as a regulator of how and where ...
Nahuel Garcia, Maiken Mellergaard, Carlos Salomon, Pilar Sepulveda, Peter Kristensen, Aase Handberg   +5 more
wiley   +1 more source

Hnf1α (MODY3) Controls Tissue-Specific Transcriptional Programs and Exerts Opposed Effects on Cell Growth in Pancreatic Islets and Liver

, 2009
Joan‐Marc Servitja, Miguel Pignatelli, M.A. Maestro, Carina Cardalda, Sylvia F. Boj, Juan José Lozano, Enrique Blanco, Amàlia Lafuente, Mark I. McCarthy, Lauro Sumoy, Roderic Guigó, Jorge Ferrer   +11 more
openalex   +1 more source

The Double‐Edged Sword of Gestational Insulin Resistance: Navigating Maternal Adaptation and Its Risks for Pregnancy and Offspring Health

Obesity Reviews, EarlyView.
ABSTRACT Although much research focuses on the effects of hyperglycemia during pregnancy on maternal and offspring health, this narrative review specifically centers on the role of insulin resistance (IR) in pregnancy complications and offspring long‐term health.
Runyu Du, Fei Wang, Ling Li, Qiuyue Wang
wiley   +1 more source