Results 141 to 150 of about 115,516 (324)

Improvement of hepatocyte engraftment by co‐transplantation with pancreatic islets in hepatocyte transplantation

, 2021
Y Saitoh, Akiko Inagaki, Ibrahim Fathi, T. Imura, Hiroyasu Nishimaki, Hiroyuki Ogasawara, Muneyuki Matsumura, Shigehito Miyagi, Yohichi Yasunami, Michiaki Unno, Takashi Kamei, Masafumi Goto   +11 more
openalex   +1 more source

Fulminant type 1 diabetes with high‐titer anti‐glutamic acid decarboxylase antibodies: Likely rapid progression from stage 2 to 3

Journal of Diabetes Investigation, EarlyView.
Abstract A 61‐year‐old man visited our hospital with a sudden onset of polydipsia and polyuria occurring 5 days prior, accompanied by a 5‐kg weight loss. A month prior, his glycated hemoglobin level was 6.2%. Precisely 8 days before the first visit, he had a fever, and hyperglycemic symptoms began shortly thereafter.
Megumi Sato, Junnosuke Miura, Hikaru Oyatsu, Yuka Yoshida, Shota Mochizuki, Michio Otsuki, Tomoko Nakagami   +6 more
wiley   +1 more source

Improvement effects of transplanting pancreatic islet that previously incubated with biomaterials on the diabetic nephropathy in STZ- diabetic rats

BMC Nephrology
Background Islet transplantation is an effective treatment for diabetes or even its complications. Aim of this study is to investigate efficacy of biomaterial treated islet transplantation on treating diabetic nephropathy. Methods Male rats were randomly
Marzieh Nemati, Zahra Hosseinzadeh, Fatemeh Nemati, Farhad Koohpeyma   +3 more
doaj   +1 more source

Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides. [PDF]

, 2018
Tissue-specific autoimmunity occurs when selected antigens presented by susceptible alleles of the major histocompatibility complex are recognized by T cells.
Anderson, Mark S, Lichti, Cheryl F, Santambrogio, Laura, Taniguchi, Ruth, Unanue, Emil R, Vomund, Anthony N, Wan, Xiaoxiao, Zakharov, Pavel N, Zinselmeyer, Bernd H   +8 more
core  

Characterization of extracellular and membrane potentials in imeglimin‐treated islets

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Glucose‐stimulated insulin secretion (GSIS) in β cells depends critically on membrane depolarization–induced Ca2+ influx. Accordingly, the electrophysiological assessment of intact islets, where β cells act as functional syncytia, is essential for evaluating insulin secretory dynamics. Imeglimin, an oral agent used in treating type 2 diabetes,
Asuka Tsurumoto, Ryota Inoue, Esther Ong Yajima, Meng Zou, Junyu Luo, Takahiro Tsuno, Emi Ishida, Kohichi Matsunaga, Jun Shirakawa   +8 more
wiley   +1 more source

Murine Pancreatic Islet Isolation [PDF]

Journal of Visualized Experiments, 2007
Gregory L, Szot, Pavel, Koudria, Jeffrey A, Bluestone   +2 more
openaire   +2 more sources

Endoscopic Ultrasound for the Management of Pancreatic Neuroendocrine Tumors: Diagnosis, Treatment, and Future Perspectives

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Pancreatic neuroendocrine tumors (PanNETs) are increasingly diagnosed, reflecting greater clinical awareness, improved imaging, and revised classification. This review summarizes evidence on epidemiology, diagnostic workup, and endoscopic ultrasound (EUS)–guided management of PanNETs, encompassing diagnostic evaluation, tissue acquisition, and
Angelo Bruni, David Meacci, Roberto Falbo, Marco Fichera, Francesco Poggioli, Riccardo Casadei, Claudio Ricci, Leonardo Henry Eusebi   +7 more
wiley   +1 more source

Epigenetic analyses suggest different pathways during pregnancy for development of Type 1 diabetes in children with high versus low‐neutral human leukocyte antigen‐risk

Journal of Internal Medicine, EarlyView.
Abstract Background and objective The development of Type 1 diabetes (T1D) is shaped by genetic predisposition and epigenetic regulation. Human leukocyte antigen (HLA) risk alleles are major genetic determinants, but the epigenetic landscape in relation to disease onset remains unclear.
Shamila D. Alipoor, Angelica Ahrens, Julia Åkesson, Thomas Hillerton, Mika Gustafsson, Maria Lerm, Johnny Ludvigsson   +6 more
wiley   +1 more source

Zinc, pancreatic islet cell function and diabetes: new insights into an old story [PDF]

, 2013
Fabrice Chimienti
openalex   +1 more source

A Review of the Effects of Maternal and Paternal Obesity on Neurodevelopmental Disorders and Related Neurobiology in Rodent and Human Offspring

Obesity Reviews, EarlyView.
ABSTRACT Obesity is one of the most prevalent health problems worldwide, and global obesity rates continue to rise. Consequently, rates of obesity in expecting mothers and fathers have also increased. The Developmental Origins of Health and Disease (DOHaD) hypothesis postulates that early‐life exposure to adverse environmental conditions contributes to
Hannah Chadwick, Victorio Bambini Junior, Neil Dawson, Cheryl A. Hawkes   +3 more
wiley   +1 more source