Results 11 to 20 of about 527,417 (294)

Postnatal Development of Endocrine Pancreatic Islets of an Egyptian One-humped Camel (Camelus dromedarius)

open access: yesSVU-International Journal of Veterinary Sciences, 2023
This study aimed to ascertain the morphological and morphometric development of pancreatic islets as well as the average levels of numerous hormones during the postnatal development of camel pancreatic islets.
Ahmed Mohamed Rashwan
doaj   +1 more source

The pancreatic islet: a micro-organ in control [PDF]

open access: yesCellR4, 2021
The islets of Langerhans constitute the endocrine pancreas which regulates blood glucose homeostasis and islet dysfunction results in diabetes. Each of the pancreatic islets constitutes an entire micro-organ with intricate cell to cell interactions and ...
M. Abdulreda, P. Berggren
doaj   +1 more source

Long-term cultures of human pancreatic islets in self-assembling peptides hydrogels

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Human pancreatic islets transplantation is an experimental therapeutic treatment for Type I Diabetes. Limited islets lifespan in culture remains the main drawback, due to the absence of native extracellular matrix as mechanical support after their ...
Amanda Marchini   +9 more
doaj   +1 more source

Generation of glucose-responsive functional islets with a three-dimensional structure from mouse fetal pancreatic cells and iPS cells in vitro. [PDF]

open access: yesPLoS ONE, 2011
Islets of Langerhans are a pancreatic endocrine compartment consisting of insulin-producing β cells together with several other hormone-producing cells. While some insulin-producing cells or immature pancreatic cells have been generated in vitro from ES ...
Hiroki Saito   +3 more
doaj   +1 more source

Decay score: a guide to the immunoreactivity of human pancreatic islets in autopsy specimen

open access: yesFolia Morphologica, 2022
BACKGROUND: The pancreas is an exo-endocrine organ that undergoes rapid autolysis soon after death, which limits its utility in academics and research.
P. K. Ravi   +3 more
doaj   +1 more source

Human alpha cell transcriptomic signatures of types 1 and 2 diabetes highlight disease-specific dysfunction pathways

open access: yesiScience, 2022
Summary: Although glucagon secretion is perturbed in both T1D and T2D, the pathophysiological changes in individual pancreatic alpha cells are still obscure.
Emanuele Bosi   +3 more
doaj   +1 more source

Dopamine modulates insulin release and is involved in the survival of rat pancreatic beta cells. [PDF]

open access: yesPLoS ONE, 2015
The local synthesis of dopamine and its effects on insulin release have been described in isolated islets. Thus, it may be accepted that dopamine exerts an auto-paracrine regulation of insulin secretion from pancreatic beta cells.
Maria Jose Garcia Barrado   +7 more
doaj   +1 more source

Bionic Organs: Shear Forces Reduce Pancreatic Islet and Mammalian Cell Viability during the Process of 3D Bioprinting

open access: yesMicromachines, 2021
Background: 3D bioprinting is the future of constructing functional organs. Creating a bioactive scaffold with pancreatic islets presents many challenges. The aim of this paper is to assess how the 3D bioprinting process affects islet viability. Methods:
Marta Klak   +12 more
doaj   +1 more source

Pancreatic Islet Transplantation

open access: yesPLoS Medicine, 2004
Islet transplantation offers hope to many patients with diabetes, who envision a life free of glucose checks and insulin injections. What are the barriers to its widespread implementation?
Mark A Naftanel, David M Harlan
openaire   +4 more sources

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