Results 21 to 30 of about 527,417 (294)
PLoS Biology, 2022 Recent evidence suggests that circadian clocks ensure temporal orchestration of lipid homeostasis and play a role in pathophysiology of metabolic diseases in humans, including type 2 diabetes (T2D).
Volodymyr Petrenko +6 more
doaj +2 more sources
Digital Imaging as a Possible Approach in Evaluation of Islet Yield
Cell Transplantation, 2003 Digital image analysis (DIA) is a new method in assessment of islet amount, which is expected to provide reliable and consistent results. We compared this method with conventional counting of small numbers of rat islets.
Peter Girman +3 more
doaj +1 more source
Вестник трансплантологии и искусственных органов, 2023 Creation of a bioartificial pancreas, including a cell-engineered construct (CEC) formed from pancreatic islets (islets of Langerhans) and a biocompatible matrix mimicking the native microenvironment of pancreatic tissue, is one of the approaches to the ...
A. S. Ponomareva +9 more
doaj +1 more source
Cell, 2019 The pancreatic islets of Langerhans regulate glucose homeostasis. The loss of insulin-producing β cells within islets results in diabetes, and islet transplantation from cadaveric donors can cure the disease. In vitro production of whole islets, not just
N. Sharon +11 more
semanticscholar +1 more source
Targeting pancreatic islet NLRP3 improves islet graft revascularization
Diabetes, 2022 <p> </p> <p>Hypoxia-induced islet cell death, caused by an insufficient revascularization of the grafts, is a major obstacle for successful pancreatic islet transplantation. Recently, it has been reported that the nucleotide-binding oligomerization domain (NOD)-like receptor protein (NLRP)3 inflammasome is expressed in pancreatic ...
Selina Wrublewsky +12 more
openaire +2 more sources
Data on morphometric analysis of the pancreatic islets from C57BL/6 and BALB/c mice
Data in Brief, 2016 The endocrine portion of the pancreas, which is characterized by pancreatic islets, has been widely investigated among different species. The BALB/c and C57BL/6 mice are extensively used in experimental research, and the morphometric differences in the ...
Thiago Aparecido da Silva +4 more
doaj +1 more source
Journal of Materials Science: Materials in Medicine, 2022 Bioengineered pancreatic β-islets have been widely advocated for the research and treatment of diabetes by offering both suitable cell culture models for the study of the pathology and the testing of new drugs and a therapy in those patients no longer ...
Valeria Perugini +2 more
doaj +1 more source
Diabetologia, 2018 Extracellular matrix (ECM) molecules are responsible for structural and biochemical support, as well as for regulation of molecular signalling and tissue repair in many organ structures, including the pancreas.
L. A. Llacua, M. Faas, P. de Vos
semanticscholar +1 more source
Journal of Diabetes Research, 2016 Variability of pancreatic donors may significantly impact the success of islet isolation. The aim of this study was to evaluate donor factors associated with isolation failure and to investigate whether immunohistology could contribute to organ selection.
Zuzana Berkova +16 more
doaj +1 more source
PanCircBase: An online resource for the exploration of circular RNAs in pancreatic islets
Frontiers in Cell and Developmental Biology, 2022 Circular RNAs (circRNAs) are a novel class of covalently closed RNA molecules that recently emerged as a critical regulator of gene expression in development and diseases.
Tanvi Sinha +5 more
doaj +1 more source