Results 241 to 250 of about 1,861,984 (306)

A Case of Metastatic Seminoma Mimicking a Primary Pancreatic Tumor. [PDF]

Cureus
Alomari A, Althunibat I, Obri MS, Curran J, Aldroubi B, Davis W, Pompa R.   +6 more
europepmc   +1 more source

The VCPIP1‐UBE3A Deubiquitination‐Ubiquitination Cascade Contributes to Castration‐Resistant Prostate Cancer Progression

Advanced Science, EarlyView.
VCIPIP1 emerges as a molecular link between protein stability and prostate cancer progression. By deubiquitinating and stabilizing UBE3A, VCIPIP1 promotes p53 degradation and progression to castration‐resistant prostate cancer. Elevated VCIPIP1 expression is associated with shorter castration‐resistant prostate cancer–free survival, highlighting the ...
Fei Lin, Wen‐Cai Zheng, Yi‐Qiu Wang, Bin Lin, Yun‐Zhi Lin, Dong‐Ning Chen, Xiao‐Dong Li, Xue‐Yi Xue, Yong Wei, Ning Xu   +9 more
wiley   +1 more source

An Unusual Cause of Pancreatic Tumor. [PDF]

Cureus
Sabri MA, Ahmed SA, Rakhange A.
europepmc   +1 more source

Biomimetic Nanoplatform for Fibrosis Remodeling and Anti‐PD‐1 Potentiation via Cu+/Ca2+ Ion Dysregulation and TGF‐β Inhibition in PDAC

Advanced Science, EarlyView.
A biomimetic nanoplatform (RPm@CC‐LY) remodels fibrotic stroma via sustained TGF‐β inhibition, triggers oxidative stress and apoptosis through Cu+‐mediated Fenton chemistry and Ca2+ overload, and reprograms macrophages and dendritic cells to boost CD8+ T cell infiltration.
Jianmei Li, Qinlong Wen, Jie Dai, Li Yang, Feng Xiong, Zhigong Wei, Xingchen Peng   +6 more
wiley   +1 more source

Metabolic landscape of the healthy pancreas and pancreatic tumor microenvironment. [PDF]

JCI Insight
Bonilla ME, Radyk MD, Perricone MD, Elhossiny AM, Harold AC, Medina-Cabrera PI, Kadiyala P, Shi J, Frankel TL, Carpenter ES, Green MD, Mitrea C, Lyssiotis CA, Pasca di Magliano M.   +13 more
europepmc   +1 more source

Non‐Invasive Assessment of Perineural Invasion Density: A Novel Marker for Prognosis and Treatment Stratification in Prostate Cancer

Advanced Science, EarlyView.
This study establishes perineural invasion density (PNID) as a superior prognostic marker in prostate cancer, outperforming conventional perineural invasion in predicting biochemical recurrence and radiographic progression. Concurrent β–blocker use is associated with favorable outcomes exclusively in High–PNID patients. An MRI–based deep learning model
Bohao Liu, Long Zhang, Weian Zhu, Meng Yang, Xiang Liu, Xiaoyang Li, Peng Qin, Zhengxu Lin, Qian Cai, Jiayu Zheng, Xiao Zhao, Chen Zou, Xuan Wen, Longhao Xu, Daqin Wu, Lin Zhang, Cuilian Zhang, Kaiwen Li, Chunhui Wang, Wenlong Zhong, Yun Luo   +20 more
wiley   +1 more source

Patient-derived pancreatic tumor bacteria exhibit oncogenic properties and are recognized by MAIT cells in tumor spheroids. [PDF]

Front Immunol
Tajpara P, Sobkowiak MJ, Healy K, Naud S, Gündel B, Halimi A, Khan ZA, Gabarrini G, Le Guyader S, Imreh G, Reisz JA, Del Chiaro M, D'Alessandro A, Heuchel R, Löhr JM, Özenci V, Sällberg Chen M.   +16 more
europepmc   +1 more source

CDK4/6 and BET inhibitors synergistically suppress pancreatic tumor growth and epithelial-to-mesenchymal transition by regulating the GSK3β-mediated Wnt/β-catenin pathway. [PDF]

Cancer Drug Resist
Gu J, Dai Z, Shen T, Chen X, Yang Z, Sun S, Chen D, Luo H, Wang X, Xu J.   +9 more
europepmc   +1 more source

A deep learning-based cascade algorithm for pancreatic tumor segmentation. [PDF]

Front Oncol
Qiu D, Ju J, Ren S, Zhang T, Tu H, Tan X, Xie F.   +6 more
europepmc   +1 more source

Regulatory network analysis of Dclk1 gene expression reveals a tuft cell-ILC2 axis that inhibits pancreatic tumor progression. [PDF]

Cell Rep
Valenti G, Laise P, Wu F, Takahashi R, Ruan T, Vasciaveo A, Jiang Z, Kobayashi H, Sunagawa M, Middelhoff M, Nienhüser H, Fu N, Malagola E, Companioni O, Hayakawa Y, Iuga AC, Califano A, Wang TC.   +17 more
europepmc   +1 more source