Results 161 to 170 of about 111,709 (349)

Crystal structure of SARS-CoV-2 papain-like protease

open access: yesActa Pharmaceutica Sinica B, 2020
Xiaopan Gao   +7 more
semanticscholar   +1 more source

Amyloid β alters vascular CaV1.2 channel spatiotemporal properties

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Amyloid‐β1‐42 (Aβ1‐42) triggers a male‐specific signalling cascade influencing CaV1.2 spatiotemporal properties in cerebral vascular smooth muscle. The signalling pathway involves NADPH oxidase (NOX)‐derived reactive oxygen species (ROS) activation of protein kinase C (PKC). Aβ1‐42 can also activate protein kinase A (PKA).
Jade L. Taylor   +5 more
wiley   +1 more source

EVALUASI DAN PENGEMBANGAN JARINGAN DISTRIBUSI AIR BERSIH DI KECAMATAN TUREN KABUPATEN MALANG [PDF]

open access: yes
Clean water is a basic need for society, but the distribution of clean water in Turen District, Malang Regency still faces several problems. This research aims to evaluate the condition of the clean water distribution network and propose development ...
Olviyani, Mustikarina
core  

PENGGUNAAN ENZIM PAPAIN TERHADAP EFISIENSI, KONVERSI PAKAN DAN PERTUMBUHAN BENIH IKAN KEURELING(TOR TAMBRA) [PDF]

open access: yes, 2015
The objective of this research was to determine the optimum dose of papain in feed on feeding efficiency and growth of Tor tambra juvenile. The measured variables were absolute growth rate, specific growth, daily growth, survival rate, feeding efficiency,
fardin aprido
core  

Parthenolide reveals an allosteric mode to inhibit the deISGylation activity of SARS-CoV‑2 papain-like protease

open access: diamond, 2022
Zhihui Zou   +11 more
openalex   +1 more source

Functional expression of inwardly rectifying and ATP‐sensitive potassium channels in human pulmonary artery smooth muscle and endothelial cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Inwardly rectifying (Kir2) and ATP‐sensitive (KATP) potassium channels are functionally expressed in human pulmonary artery endothelial and smooth muscle cells. The schematic illustrates how Kir2‐ and KATP‐mediated K+ efflux contributes to VM regulation and pulmonary vascular tone.
Bianca Barreira   +7 more
wiley   +1 more source

Exploration of a mutant enzyme protein with active site fluctuations at 330 K via machine learning and molecular dynamics simulations

open access: yesAIP Advances
Control of active site fluctuations in enzyme proteins would significantly expand their application fields. Because papain typically has higher activity at 330 K, shifting the temperature to 330 K may help to expand its range of use in medical treatment,
Katsuhiko Nishiyama
doaj   +1 more source

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