Interplay between volemic balance and the intestinal tract: insights on biomarkers and diagnostic tests used to assess intestinal morphofunctional barrier. [PDF]
Braz J Med Biol ResNeto VLM +6 more
europepmc +1 more source
Insights Into Gut Barrier Dysfunction and Metabolic Alterations in Mycophenolate-Induced Enteropathy. [PDF]
Basic Clin Pharmacol ToxicolBrossier C +6 more
europepmc +1 more source
Editorial: Regulation of permeability of tight junctions. [PDF]
Front Cell Dev BiolMierke CT.
europepmc +1 more source
Effect of Lactobacilli on Paracellular Permeability in the Gut [PDF]
Nutrients, 2011 Paracellular permeability is determined by the complex structures of junctions that are located between the epithelial cells. Already in 1996, it was shown that the human probiotic strain Lactobacillus plantarum 299v and the rat-originating strain Lactobacillus reuteri R2LC could reduce this permeability in a methotrexate-induced colitis model in the ...
Siv Ahrné
exaly +3 more sources
Colonic paracellular permeability and circulating zonulin-related proteins [PDF]
Scandinavian Journal of Gastroenterology, 2021 Irritable bowel syndrome (IBS) is a gut-brain disorder associated with increased gut permeability. Zonulin has been suggested to regulate the gut barrier and claimed to be pre-haptoglobin 2 (pre-HP2) and circulating zonulin is often used as a proxy for gastrointestinal permeability.
Felipe Meira De-Faria +2 more
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Related searches:
Regulation of paracellular permeability: factors and mechanisms
Molecular Biology Reports, 2013Epithelial permeability is composed of transcellular permeability and paracellular permeability. Paracellular permeability is controlled by tight junctions (TJs). Claudins and occludin are two major transmembrane proteins in TJs, which directly determine the paracellular permeability to different ions or large molecules.
Yan-Jun Hu, Fu-Qing Tan, Wan-Xi Yang
exaly +3 more sources
Modulation of epithelial and endothelial paracellular permeability by leukocytes
Advanced Drug Delivery Reviews, 2000The tight junction acts as a regulated barrier for diffusion of ions, larger solutes, and migration of leukocytes through the paracellular space. Barrier function varies with the tissue type, and positively correlates with the number and complexity of tight junction strand formation.
Charles A Parkos
exaly +3 more sources
Multiple domains of occludin are involved in the regulation of paracellular permeability
Journal of Cellular Biochemistry, 2000Tight junctions form selective paracellular diffusion barriers that regulate the diffusion of solutes across epithelia and constitute intramembrane diffusion barriers that prevent the intermixing of apical and basolateral lipids in the extracytoplasmic leaflet of the plasma membrane.
Maria S Balda +2 more
exaly +3 more sources
Barriers to paracellular permeability in rabbit esophageal epithelium
Gastroenterology, 1992Morphological and electrophysiological techniques were used to define the location and nature of the barriers to diffusion across the intercellular space (paracellular pathway) of rabbit esophageal epithelium. Transmission electron microscopy and light microscopy coupled with histochemistry identified a series of tight junctions and an intercellular ...
R C, Orlando +3 more
openaire +2 more sources
Endotoxin increases paracellular permeability of isolated rat hepatocyte couplets
Hepatology Research, 2001Hyperbilirubinemia is frequently associated with endotoxemia. Regurgitation of bile constituents including bilirubin into the sinusoidal space is prevented by tight junctions which maintain paracellular permeability between hepatocytes. To investigate the mechanism of endotoxin-associated hyperbilirubinemia, we have studied the changes in paracellular ...
Shotaro Sakisaka +2 more
exaly +3 more sources