Results 31 to 40 of about 328,971 (180)

The sweet life: diet sugar concentration influences paracellular glucose absorption [PDF]

, 2008
Small birds and bats face strong selection pressure to digest food rapidly in order to reduce digesta mass carried during flight. One mechanism is rapid absorption of a high proportion of glucose via the paracellular pathway (transfer between epithelial ...
McWhorter, T., Fleming, P., P. A Fleming, Purchase, Cromwell, Fleming, P.A., Napier, K., Nicolson, S., Nicolson, S.W., C. Purchase, K. R Napier, Purchase, C., Napier, Kathryn R., S. W Nicolson, Nicolson, Sue W., T. J McWhorter, McWhorter, T.J., McWhorter, Todd J., Napier, K.R., Fleming, Patricia A.   +18 more
core   +1 more source

Leucokinin Increases Paracellular Permeability in Insect Malpighian Tubules [PDF]

Journal of Experimental Biology, 1996
ABSTRACT There are two major transport pathways across epithelia: a transcellular pathway through cells and a paracellular pathway between cells. Previous electrophysiological studies in mosquito Malpighian tubules suggested that the neuropeptide leucokinin-VIII (LK-VIII) increases the chloride permeability of the paracellular pathway ...
, Wang, , Rubenfeld, , Hayes, , Beyenbach   +3 more
openaire   +2 more sources

Role of claudins in renal calcium handling

Nefrología (English Edition), 2015
Paracellular channels occurring in tight junctions play a major role in transepithelial ionic flows. This pathway includes a high number of proteins, such as claudins.
Armando Luis Negri
doaj   +1 more source

Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family [PDF]

, 2009
Background: Tight junctions are an intercellular adhesion complex of epithelial and endothelial cells, and form a paracellular barrier that restricts the diffusion of solutes on the basis of size and charge.
Rodrigues, N.T.L., Maria S Balda, Nelio TL Rodrigues, Matter Karl, Balda Maria S, Karl Matter, Steed, E., Balda, M.S., Matter, K., Steed Emily, Rodrigues Nelio TL, Emily Steed   +11 more
core   +1 more source

An on-chip model of protein paracellular and transcellular permeability in the microcirculation [PDF]

Biomaterials, 2019
Recent therapeutic success of large-molecule biologics has led to intense interest in assays to measure with precision their transport across the vascular endothelium and into the target tissue. Most current in vitro endothelial models show unrealistically large permeability coefficients due to a non-physiological paracellular transport.
Offeddu, Giovanni, Haase, Kristina Michelle, Gillrie, Mark Robert, Li, Ran, Morozova, Olga, Hickman, Dean, Knutson, Charles G., Kamm, Roger Dale   +7 more
openaire   +4 more sources

The effect of claudin-15 deletion on cationic selectivity and transport in paracellular pathways of the cecum and large intestine

Scientific Reports, 2023
The large intestine plays a pivotal role in water and electrolyte balance. Paracellular transport may play a role in ion transport mechanisms in the cecum and large intestine; however, these molecular mechanisms and their physiological roles have not ...
Wendy Hempstock, Nozomi Nagata, Noriko Ishizuka, Hisayoshi Hayashi   +3 more
doaj   +1 more source

3D visualization of trans-syncytial nanopores provides a pathway for paracellular diffusion across the human placental syncytiotrophoblast

iScience, 2022
Summary: The placental syncytiotrophoblast, a syncytium without cell-cell junctions, is the primary barrier between the mother and the fetus. Despite no apparent anatomical pathway for paracellular diffusion of solutes across the syncytiotrophoblast ...
Rohan M. Lewis, Harikesan Baskaran, Jools Green, Stanimir Tashev, Eleni Palaiologou, Emma M. Lofthouse, Jane K. Cleal, Anton Page, David S. Chatelet, Patricia Goggin, Bram G. Sengers   +10 more
doaj   +1 more source

Interleukin-6 Trans-Signaling Mediated Regulation of Paracellular Permeability in Human Retinal Endothelial Cells

, 2021
Long-term hyperglycemia-mediated oxidative stress and inflammation lead to the blood-retinal barrier (BRB) dysfunction and increased vascular permeability associated with diabetic retinopathy (DR).
Ashok Sharma, Shruti Sharma, Rebekah Robinson, Joshua Glass, Tae-Jin Lee   +4 more
core   +1 more source

Intestinal barrier function and absorption in pigs after waeaning: a review [PDF]

, 2011
Under commercial conditions, weaning of piglets is associated with social, environmental and dietary stress. Consequently, small-intestinal barrier and absorptive functions deteriorate within a short time after weaning.
Wijtten, P.J.A., Verstegen, M.W.A., Meulen, J., van der   +2 more
core   +1 more source

Arachidonic acid cascade and epithelial barrier function during Caco-2 cell differentiation

Journal of Lipid Research, 2006
The small intestinal epithelium is a highly dynamic system continuously renewed by a process involving cell proliferation and differentiation. The intestinal epithelium constitutes a permeability barrier regulating the vectorial transport of ions, water,
Raquel Martién-Venegas, Soènia Roig-Peérez, Ruth Ferrer, Juan Joseé Moreno   +3 more
doaj   +1 more source