A novel role for aquaporin-5 in enhancing microtubule organization and stability. [PDF]
PLoS ONE, 2012 Aquaporin-5 (AQP5) is a water-specific channel located on the apical surface of airway epithelial cells. In addition to regulating transcellular water permeability, AQP5 can regulate paracellular permeability, though the mechanisms by which this occurs ...
Venkataramana K Sidhaye +8 more
doaj +1 more source
Altered Transendothelial Transport of Hormones as a Contributor to Diabetes [PDF]
Diabetes & Metabolism Journal, 2014 The vascular endothelium is a dynamic structure responsible for the separation and regulated movement of biological material between circulation and interstitial fluid.
Nanyoung Yoon +4 more
doaj +1 more source
Paracellular Permeability of Bronchial Epithelium is Controlled by CFTR [PDF]
Cellular Physiology and Biochemistry, 2011 In normal airway epithelium, the cystic fibrosis transmembrane conductance regulator (CFTR) transports Cl(-) ions to the apical surface of the epithelium paralleled by the flow of water through transcellular and paracellular pathways. The hypothesis was tested whether CFTR not only regulates the transcellular but also the paracellular shunt pathway ...
Nelly, Weiser +6 more
openaire +2 more sources
Paracellular transport through healthy and cystic fibrosis bronchial epithelial cell lines--do we have a proper model? [PDF]
PLoS ONE, 2014 It has been reported recently that the cystic fibrosis transmembrane conductance regulator (CFTR) besides transcellular chloride transport, also controls the paracellular permeability of bronchial epithelium.
Natalia Molenda +5 more
doaj +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2021 Background & Aims: Tight junctions form a barrier to the paracellular passage of luminal antigens. Although most tight junction proteins reside within the apical tight junction complex, claudin-18 localizes mainly to the basolateral membrane where ...
Tyler J. Caron +9 more
doaj +1 more source
GLP-2 Acutely Prevents Endotoxin-Related Increased Intestinal Paracellular Permeability in Rats. [PDF]
Dig Dis Sci, 2020 BackgroundCirculating endotoxin (lipopolysaccharide, LPS) increases the gut paracellular permeability. We hypothesized that glucagon-like peptide-2 (GLP-2) acutely reduces LPS-related increased intestinal paracellular permeability by a mechanism ...
Maruta K +7 more
europepmc +2 more sources
Capacity for absorption of water-soluble secondary metabolites greater in birds than in rodents. [PDF]
PLoS ONE, 2012 Plant secondary metabolites (SMs) are pervasive in animal foods and potentially influence feeding behavior, interspecies interactions, and the distribution and abundance of animals.
William H Karasov +5 more
doaj +1 more source
Fecal and Circulating Biomarkers for the Non-Invasive Assessment of Intestinal Permeability
Diagnostics, 2023 The study of intestinal permeability is gaining growing interest due to its relevance in the onset and progression of several gastrointestinal and non-gastrointestinal diseases.
Nuria Perez-Diaz-del-Campo +3 more
doaj +1 more source
Permeability of hydrogel cultures to paracellular tracers.
, 2023 Permeability of hydrogel cultures to paracellular tracers.
Ignacio A. Romero (305341) +6 more
core +1 more source
Differential effects of TNF (TNFSF2) and IFN-γ on intestinal epithelial cell morphogenesis and barrier function in three-dimensional culture. [PDF]
PLoS ONE, 2011 BackgroundThe cytokines TNF (TNFSF2) and IFNγ are important mediators of inflammatory bowel diseases and contribute to enhanced intestinal epithelial permeability by stimulating apoptosis and/or disrupting tight junctions.
Kati Juuti-Uusitalo +7 more
doaj +1 more source