Results 41 to 50 of about 328,971 (180)

Fructose transport-deficient Staphylococcus aureus reveals important role of epithelial glucose transporters in limiting sugar-driven bacterial growth in airway surface liquid. [PDF]

open access: yes, 2014
Hyperglycaemia as a result of diabetes mellitus or acute illness is associated with increased susceptibility to respiratory infection with Staphylococcus aureus.
Farrant, MR   +13 more
core   +1 more source

Lipid peroxidation induced by DHA enrichment modifies paracellular permeability in Caco-2 cells

open access: yesJournal of Lipid Research, 2004
Dietary enrichment with docosahexaenoic acid (DHA) has numerous beneficial effects on health. However, the intake of high doses of polyunsaturated fatty acids can promote lipid peroxidation and the subsequent propagation of oxygen radicals.
Sònia Roig-Pérez   +3 more
doaj   +1 more source

Reconstitution of functional tight junctions with individual claudin subtypes in epithelial cells

open access: yesCell Structure and Function, 2022
The claudin family of membrane proteins is responsible for the backbone structure and function of tight junctions (TJs), which regulate the paracellular permeability of epithelia.
Mikio Furuse   +8 more
doaj   +1 more source

Tight junction-related barrier contributes to the electrophysiological asymmetry across vocal fold epithelium. [PDF]

open access: yesPLoS ONE, 2012
Electrophysiological homeostasis is indispensable to vocal fold hydration. We investigate tight junction (TJ)-associated components, occludin and ZO-1, and permeability with or without the challenge of a permeability-augmenting agent, histamine.
Qianru Zhang, Kimberly Fisher
doaj   +1 more source

A postbiotic fermented oat gruel may have a beneficial effect on the colonic mucosal barrier in patients with irritable bowel syndrome

open access: yesFrontiers in Nutrition, 2022
BackgroundImpaired intestinal permeability and microbial dysbiosis are important pathophysiological mechanisms underlying irritable bowel syndrome (IBS).
Olga Bednarska   +6 more
doaj   +1 more source

Developmental changes in rabbit proximal straight tubule paracellular permeability [PDF]

open access: yesAmerican Journal of Physiology-Renal Physiology, 2002
The early proximal tubule preferentially reabsorbs organic solutes and bicarbonate over chloride ions, resulting in a luminal fluid with a higher chloride concentration than that in blood. From this late proximal tubular fluid, one-half of NaCl reabsorption by the adult proximal tubule is active and transcellular and one-half is passive and ...
Raymond, Quigley, Michel, Baum
openaire   +2 more sources

The paracellular permeability of opossum kidney cells, a proximal tubule cell line [PDF]

open access: yes, 1999
The paracellular permeability of opossum kidney cells, a proximal tubule cell line.BackgroundThe regulation of the unusually leaky paracellular pathway of the proximal tubule is poorly understood partially because of the lack of an appropriate in vitro ...
Ramsey, Carla R.   +2 more
core   +1 more source

Comparison of Various Cell Lines and Three-Dimensional Mucociliary Tissue Model Systems to Estimate Drug Permeability Using an In Vitro Transport Study to Predict Nasal Drug Absorption in Rats

open access: yesPharmaceutics, 2020
Recently, various types of cultured cells have been used to research the mechanisms of transport and metabolism of drugs. Although many studies using cultured cell systems have been published, a comparison of different cultured cell systems has never ...
Tomoyuki Furubayashi   +8 more
doaj   +1 more source

PAR-2-induced colonic inflammation does not depend upon paracellular permeability and lymphocyte infiltration [PDF]

open access: yes, 2002
PAR-2-induced colonic inflammation does not depend upon paracellular permeability and lymphocyte infiltration.
Ferrier, Laurent   +4 more
core   +3 more sources

VEGF isoforms have differential effects on permeability of human pulmonary microvascular endothelial cells

open access: yesRespiratory Research, 2017
Background Alternative splicing of Vascular endothelial growth factor-A mRNA transcripts (commonly referred as VEGF) leads to the generation of functionally differing isoforms, the relative amounts of which have potentially significant physiological ...
Khadija Ourradi   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy