Results 61 to 70 of about 41,666 (255)

Cytokine tuning of intestinal epithelial function [PDF]

open access: yes, 2018
The intestine serves as both our largest single barrier to the external environment and the host of more immune cells than any other location in our bodies.
Andrews, Caroline   +2 more
core   +4 more sources

Intestinal barrier function and absorption in pigs after waeaning: a review [PDF]

open access: yes
Under commercial conditions, weaning of piglets is associated with social, environmental and dietary stress. Consequently, small-intestinal barrier and absorptive functions deteriorate within a short time after weaning.
Meulen, J., van der   +2 more
core   +2 more sources

Biomarkers for monitoring intestinal health in poultry : present status and future perspectives [PDF]

open access: yes, 2018
Intestinal health is determined by host (immunity, mucosal barrier), nutritional, microbial and environmental factors. Deficiencies in intestinal health are associated with shifts in the composition of the intestinal microbiome (dysbiosis), leakage of ...
Antonissen, Gunther   +6 more
core   +3 more sources

Feeding of deoxynivalenol increases the intestinal paracellular permeability of broiler chickens [PDF]

open access: yesArchives of Toxicology, 2019
In recent years, the deleterious effects attributed to mycotoxins, in particular on the intestine, faced increased attention and it was shown that deoxynivalenol (DON) causes adverse effects on gut health. In this context, it has been repeatedly reported that DON can alter the intestinal morphology, disrupt the intestinal barrier and reduce nutrient ...
Wageha A, Awad   +5 more
openaire   +2 more sources

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

open access: yesAdvanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang   +4 more
wiley   +1 more source

Permeability of Epithelial/Endothelial Barriers in Transwells and Microfluidic Bilayer Devices

open access: yesMicromachines, 2019
Lung-on-a-chip (LoC) models hold the potential to rapidly change the landscape for pulmonary drug screening and therapy, giving patients more advanced and less invasive treatment options.
Timothy S. Frost   +3 more
doaj   +1 more source

SHED-derived exosomes ameliorate hyposalivation caused by Sjögren's syndrome via Akt/GSK-3β/Slug-mediated ZO-1 expression

open access: yesChinese Medical Journal, 2023
. Background:. Sjögren's syndrome (SS) is an autoimmune disorder characterized by sicca syndrome and/or systemic manifestations. The treatment is still challenging.
Zhihao Du   +6 more
doaj   +1 more source

MicroRNA-210 Suppresses Junction Proteins and Disrupts Blood-Brain Barrier Integrity in Neonatal Rat Hypoxic-Ischemic Brain Injury. [PDF]

open access: yes, 2017
Cerebral edema, primarily caused by disruption of the blood-brain barrier (BBB), is one of the serious complications associated with brain injury in neonatal hypoxic-ischemic encephalopathy (HIE).
Dasgupta, Chiranjib   +4 more
core   +2 more sources

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

open access: yesAdvanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li   +9 more
wiley   +1 more source

Modulation of urinary bladder paracellular permeability by stretch

open access: yesThe FASEB Journal, 2012
In response to bladder filling and voiding, umbrella cells undergo changes in cell‐shape and vesicular trafficking. However, it is not known how filling/voiding impact paracellular transport in these cells. To investigate how changes in umbrella cell stretch affect paracellular permeability, bladder mucosa was mounted in Ussing ...
Marcelo D Carattino   +3 more
openaire   +1 more source

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