Results 71 to 80 of about 328,971 (180)

Neural control of intestinal ion transport and paracellular permeability is altered by nutritional status

open access: yes, 2000
This study examined the effect of fasting on the neural control of ion transport and paracellular permeability in piglet jejunum. Muscle-stripped tissues from fed or 48-h fasted piglets were mounted in Ussing chambers. Neural blockade with tetrodotoxin (
Ursula L. Hayden, Hannah V. Carey
core   +1 more source

Effect of colonic bacterial metabolites on Caco-2 cell paracellular permeability in vitro

open access: yes, 2008
One common effect of tumor promoters is increased tight junction (TJ) permeability. TJs are responsible for paracellular permeability and integrity of the barrier function. Occludin is one of the main proteins responsible for TJ structure.
Kurth, M.J.   +4 more
core   +1 more source

Structure−Activity Relationship for Enhancement of Paracellular Permeability across Caco-2 Cell Monolayers by 3-Alkylamido-2-alkoxypropylphosphocholines

open access: yes, 2016
Paracellular permeability enhancers have been used to improve the oral bioavailability of hydrophilic drugs; however, the mechanism of action of many enhancers is poorly understood. In this study, highly potent enhancers of paracellular permeability were
Peter Ward (2913677)   +6 more
core   +1 more source

Paracellular permeability of corneal and conjunctival epithelia.

open access: yesInvestigative ophthalmology & visual science, 1989
The paracellular permeability of normal rabbit cornea and conjunctiva was studied in vivo and in vitro. After intravenous administration, horseradish peroxidase was found to percolate to the intercellular space of conjunctival epithelia and was restricted by the tight junctions of the superficial epithelium.
A J, Huang, S C, Tseng, K R, Kenyon
openaire   +1 more source

Albuterol Modulates Its Own Transepithelial Flux via Changes in Paracellular Permeability

open access: yes, 2012
Although inhaled bronchodilators are commonly used in the treatment of airway disease to dilate airway smooth muscle, little is known regarding the mechanisms that regulate albuterol movement across the epithelium to reach its target, the airway smooth ...
Salathe, Matthias   +9 more
core   +1 more source

Paracellular transport of phosphate along the intestine [PDF]

open access: yes, 2019
Inorganic phosphate (P) is crucial for many biological functions, such as energy metabolism, signal transduction, and pH buffering. Efficient systems must exist to ensure sufficient supply for the body of P from diet.
Günzel, Dorothee; https://orcid.org/   +5 more
core   +1 more source

Endothelial paracellular permeability assay v1

open access: yes, 2017
The human umbilical vein endothelial cell line EA.hy926 (ATCC; Mannasas, VA, USA) was cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented with 10% fetal calf serum (FCS) in an atmosphere of 5% CO2/95% air and 37°C. EA.hy926 cells (105cells/plate) were seeded in transwell inserts (Corning® BiocoatTM Cell Culture Inserts Collagen, Type I Rat
openaire   +1 more source

Regulation of paracellular permeability in Caco-2 cell monolayers by protein kinase C

open access: yes, 1993
Caco-2 cells are an enterocyte-like cell line derived from a human colonic adenocarcinoma. Paracellular permeability was assessed in monolayers of these cells by transmonolayer resistance and by the permeation of [3H]mannitol across the monolayer ...
J. Turk   +3 more
core   +1 more source

A dual-tracer method for differentiating transendothelial transport from paracellular leakage in vivo and in vitro

open access: yesFrontiers in Physiology, 2012
Inflammation-induced impaired function of vascular endothelium may cause leakage of plasma proteins that can lead to edema. Proteins may leave the vascular lumen through two main paracellular and transcellular pathways.
Nino eMuradashvili   +2 more
doaj   +1 more source

Effect of changes in paracellular permeability on airspace liquid clearance: role of glucose transport

open access: yes, 1996
The role of the pulmonary sodium-glucose cotransport is unknown. We hypothesized that altering glucose balance (the level of passive vs. active transport) across the airspace epithelium might affect luminal liquid clearance (Jw).
G. Saumon, G. Martet
core   +1 more source

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