Results 51 to 60 of about 666,834 (274)

Arachidonic acid cascade and epithelial barrier function during Caco-2 cell differentiation

Journal of Lipid Research, 2006
The small intestinal epithelium is a highly dynamic system continuously renewed by a process involving cell proliferation and differentiation. The intestinal epithelium constitutes a permeability barrier regulating the vectorial transport of ions, water,
Raquel Martién-Venegas, Soènia Roig-Peérez, Ruth Ferrer, Juan Joseé Moreno   +3 more
doaj   +1 more source

Anthocyanins inhibit tumor necrosis alpha-induced loss of Caco-2 cell barrier integrity [PDF]

, 2017
An increased permeability of the intestinal barrier is proposed as a major event in the pathophysiology of conditions characterized by chronic gut inflammation.
Anderson, Maureen, Cremonini, Eleonora, Fraga, César Guillermo, Hester, Shelly N., Mastaloudis, Angela, Oteiza, Patricia Isabel, Verstraeten, Sandra Viviana, Waterhouse, Andrew L., Wood, Steven M.   +8 more
core   +1 more source

Lipid peroxidation induced by DHA enrichment modifies paracellular permeability in Caco-2 cells

Journal of Lipid Research, 2004
Dietary enrichment with docosahexaenoic acid (DHA) has numerous beneficial effects on health. However, the intake of high doses of polyunsaturated fatty acids can promote lipid peroxidation and the subsequent propagation of oxygen radicals.
Sònia Roig-Pérez, Francesc Guardiola, Miquel Moretó, Ruth Ferrer   +3 more
doaj   +1 more source

Curcumin Mitigates Immune-Induced Epithelial Barrier Dysfunction by Campylobacter jejuni [PDF]

, 2019
Campylobacter jejuni (C. jejuni) is the most common cause of foodborne gastroenteritis worldwide. The bacteria induce diarrhea and inflammation by invading the intestinal epithelium. Curcumin is a natural polyphenol from turmeric rhizome of Curcuma longa,
Bereswill, Stefan, Butkevych, Eduard, Bücker, Roland, Fromm, Anja, Golz, Julia C., Heimesaat, Markus M., Kehrenberg, Corinna, Kittler, Sophie, Lobo de Sá, Fábia Daniela, Moos, Verena, Mousavi, Soraya, Nattramilarasu, Praveen Kumar, Schulzke, Jörg-Dieter, Seinige, Diana, Stingl, Kerstin   +14 more
core   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Reconstitution of functional tight junctions with individual claudin subtypes in epithelial cells

Cell Structure and Function, 2022
The claudin family of membrane proteins is responsible for the backbone structure and function of tight junctions (TJs), which regulate the paracellular permeability of epithelia.
Mikio Furuse, Daiki Nakatsu, Wendy Hempstock, Shiori Sugioka, Noriko Ishizuka, Kyoko Furuse, Taichi Sugawara, Yugo Fukazawa, Hisayoshi Hayashi   +8 more
doaj   +1 more source

Fructose transport-deficient Staphylococcus aureus reveals important role of epithelial glucose transporters in limiting sugar-driven bacterial growth in airway surface liquid. [PDF]

, 2014
Hyperglycaemia as a result of diabetes mellitus or acute illness is associated with increased susceptibility to respiratory infection with Staphylococcus aureus.
A Brennan, A Sheludiakova, A Tamer, AA Pezzulo, AL Brennan, Alex J. McCarthy, AR Manolescu, BJ Philips, BJ Philips, BP Cummings, C Siebold, CA Colville, CA Merlo, CI Cheeseman, Daniela Braun, Deborah L. Baines, DM Wood, E Kupeli, EH Baker, EH Baker, Emma H. Baker, FV Donenko, G Saumon, HL Kornberg, I Knezevic, J Plumbridge, James P. Garnett, Jodi A. Lindsay, JP Garnett, JP Garnett, JP Garnett, JP Garnett, K Seidl, K Seidl, KC Strasters, KK Kalsi, KK Kalsi, KL Stanhope, M Faiyaz-Ul-Haque, Matthew R. Farrant, MM Myerburg, MT Le, ND Meadow, PA Dawson, PD Fey, PM Barker, PN Wahjudi, R Pyla, RJ Lee, SJ Curtis, YC Lee   +50 more
core   +1 more source

Tight junction-related barrier contributes to the electrophysiological asymmetry across vocal fold epithelium. [PDF]

PLoS ONE, 2012
Electrophysiological homeostasis is indispensable to vocal fold hydration. We investigate tight junction (TJ)-associated components, occludin and ZO-1, and permeability with or without the challenge of a permeability-augmenting agent, histamine.
Qianru Zhang, Kimberly Fisher
doaj   +1 more source

A postbiotic fermented oat gruel may have a beneficial effect on the colonic mucosal barrier in patients with irritable bowel syndrome

Frontiers in Nutrition, 2022
BackgroundImpaired intestinal permeability and microbial dysbiosis are important pathophysiological mechanisms underlying irritable bowel syndrome (IBS).
Olga Bednarska, Olga Biskou, Hans Israelsen, Martin E. Winberg, Susanna Walter, Susanna Walter, Åsa V. Keita   +6 more
doaj   +1 more source

Do We Have a Proper Model? [PDF]

, 2014
It has been reported recently that the cystic fibrosis transmembrane conductance regulator (CFTR) besides transcellular chloride transport, also controls the paracellular permeability of bronchial epithelium.
Günzel, Dorothee, Kusche-Vihrog, Kristina, Molenda, Natalia, Schillers, Hermann, Urbanova, Katarina, Weiser, Nelly   +5 more
core   +1 more source