Results 91 to 100 of about 206,427 (382)

Investigating the association between obesity and asthma in 6- to 8-year-old Saudi children:a matched case-control study [PDF]

, 2014
Background: Previous studies have demonstrated an association between obesity and asthma, but there remains considerable uncertainty about whether this reflects an underlying causal relationship.
A Bener, A Bereket, A Deesomchok, A Sood, AA Mamun, AB Hill, C Anandan, CA Camargo Jr, CAJ Camargo, CL Ogden, D Sole, DS Freedman, HR Anderson, IA Janahi, JA Castro-Rodriguez, JJ Reilly, JL Clausen, JL Santos, JM Tanner, JV Durnin, JÖ Magnusson, KG Tantisira, KM Baker, L Trasande, LG Hersoug, M Badran, M Nahhas, M Stumvoll, M Weiss, MR Miller, N Beydon, N Hatipoglu, N Scopinaro, N Vangeepuram, P Bustos, PM Matricardi, RB Noal, RJ Hancox, S Kannan, SA Shore, SA Shore, SH Arshad, SO Shaheen, ST Weiss, ST Weiss, TL Guidotti, TS Hallstrand, TZ Kajbaf, V Mishra, VE Cassol, W Nystad, Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC, Y Mohammad   +52 more
core   +2 more sources

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source

Melt Crystallization for Paracetamol Polymorphism

Crystal Growth & Design, 2019
Trimorphic paracetamol, one of the most commonly used analgesic and antipyretic drugs, has been a model system for studying transformations among phases of molecular crystalline materials.
A. Shtukenberg, Melissa Tan, Leslie Vogt-Maranto, E. Chan, Wen-Kai Xu, Jingxiang Yang, M. Tuckerman, C. Hu, B. Kahr   +8 more
semanticscholar   +1 more source

Effect of Durian Fruit Juice (Durio Zibethinus Murr.) to Pharmacokinetic Profile of Paracetamol on Wistar Male Rats (Rattus Norvegicus L.) [PDF]

, 2013
Paracetamol is widely used as analgesic and antipyretic agent in treatment of pain and fever. Paracetamol has interaction with carbohydrates and alcohol. Durian is the fruit native of Indonesia, that contain carbohydrates and alcohol.
Andrie, M. (Mohamad), Simaremare, P. (Pinondang), Wijianto, B. (Bambang)   +2 more
core  

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

British Journal of Clinical Pharmacology, EarlyView.
Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort, Marella C. E. van Ruissen, Lisanne C. A. Smidt, Naomi B. Klarenbeek, Philip H. K. Kremer, Manon A. A. Jansen, Jacobus Burggraaf, Joop M. A. van Gerven, Matthijs Moerland   +8 more
wiley   +1 more source

Study of Paracetamol Processing within Indonesian Perspectives [PDF]

E3S Web of Conferences
Antipyretic paracetamol, or acetaminophen is a popular pharmaceutical in the global market. However, some countries have limited capacity to produce their own need of this drug due to several reasons.
Kurniawansyah Firman, Idzati Eka M., Ni’mah Hikmatun   +2 more
doaj   +1 more source

Assessment of Paracetamol Toxic Effects under Varying Seawater pH Conditions on the Marine Polychaete Hediste diversicolor Using Biochemical Endpoints [PDF]

, 2022
David Daniel, Bruno Nunes, Edgar Pinto, Isabel M.P.L.V.O. Ferreira, Alberto Teodorico Correia   +4 more
openalex   +1 more source

Effect of Solution pH on the Adsorption of Paracetamol on Chemically Modified Activated Carbons

Molecules, 2017
Paracetamol adsorption in acidic, neutral and basic media on three activated carbons with different chemistry surfaces was studied. A granular activated carbon (GAC) was prepared from coconut shell; starting from this sample, an oxidized activated carbon
Valentina Bernal, A. Erto, L. Giraldo, J. Moreno-Piraján   +3 more
semanticscholar   +1 more source

Direct measurement of molecular mobility and crystallisation of amorphous pharmaceuticals using terahertz spectroscopy. [PDF]

, 2016
Despite much effort in the area, no comprehensive understanding of the formation and behaviour of amorphous solids has yet been achieved. This severely limits the industrial application of such materials, including drug delivery where, in principle ...

core   +2 more sources

Pregabalin dependence, withdrawal, suicidality and psychosis reports: A disproportionality analysis of the Australian adverse events database

British Journal of Clinical Pharmacology, EarlyView.
Aims Globally, Australia has the highest per capita consumption rate of pregabalin, commonly prescribed for neuropathic pain. Emerging evidence suggests pregabalin may be associated with the onset or recurrence of several potentially life‐threatening psychiatric events in some individuals.
Amy G. McNeilage, Ali Gholamrezaei, Bridin Murnion, Suzanne Nielsen, Claire E. Ashton‐James   +4 more
wiley   +1 more source